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A cholesterol-binding bacterial toxin provides a strategy for identifying a specific Scap inhibitor that blocks lipid synthesis in animal cells.
Proc Natl Acad Sci U S A. 2024 Feb 13;121(7):e2318024121. doi: 10.1073/pnas.2318024121. Epub 2024 Feb 8.
Proc Natl Acad Sci U S A. 2024.
PMID: 38330014
Free PMC article.
An AlphaScreen Assay for the Discovery of Synthetic Chemical Inhibitors of Glucagon Production.
Evans MR, Wei S, Posner BA, Unger RH, Roth MG.
Evans MR, et al.
J Biomol Screen. 2016 Apr;21(4):325-32. doi: 10.1177/1087057115622201. Epub 2015 Dec 16.
J Biomol Screen. 2016.
PMID: 26676097
Free PMC article.
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Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer.
Kim HS, Mendiratta S, Kim J, Pecot CV, Larsen JE, Zubovych I, Seo BY, Kim J, Eskiocak B, Chung H, McMillan E, Wu S, De Brabander J, Komurov K, Toombs JE, Wei S, Peyton M, Williams N, Gazdar AF, Posner BA, Brekken RA, Sood AK, Deberardinis RJ, Roth MG, Minna JD, White MA.
Kim HS, et al.
Cell. 2013 Oct 24;155(3):552-66. doi: 10.1016/j.cell.2013.09.041. Epub 2013 Oct 24.
Cell. 2013.
PMID: 24243015
Free PMC article.
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