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A marine microbiome antifungal targets urgent-threat drug-resistant fungi.
Zhang F, Zhao M, Braun DR, Ericksen SS, Piotrowski JS, Nelson J, Peng J, Ananiev GE, Chanana S, Barns K, Fossen J, Sanchez H, Chevrette MG, Guzei IA, Zhao C, Guo L, Tang W, Currie CR, Rajski SR, Audhya A, Andes DR, Bugni TS. Zhang F, et al. Science. 2020 Nov 20;370(6519):974-978. doi: 10.1126/science.abd6919. Science. 2020. PMID: 33214279 Free PMC article.
Bacillibactins E and F from a Marine Sponge-Associated Bacillus sp.
Wu Q, Throckmorton K, Maity M, Chevrette MG, Braun DR, Rajski SR, Currie CR, Thomas MG, Bugni TS. Wu Q, et al. J Nat Prod. 2021 Jan 22;84(1):136-141. doi: 10.1021/acs.jnatprod.0c01170. Epub 2020 Dec 18. J Nat Prod. 2021. PMID: 33337146 Free PMC article.
NMR reveals a dynamic allosteric pathway in thrombin.
Handley LD, Fuglestad B, Stearns K, Tonelli M, Fenwick RB, Markwick PR, Komives EA. Handley LD, et al. Sci Rep. 2017 Jan 6;7:39575. doi: 10.1038/srep39575. Sci Rep. 2017. PMID: 28059082 Free PMC article.
The BRPF1 bromodomain is a molecular reader of di-acetyllysine.
Obi JO, Lubula MY, Cornilescu G, Henrickson A, McGuire K, Evans CM, Phillips M, Boyson SP, Demeler B, Markley JL, Glass KC. Obi JO, et al. Curr Res Struct Biol. 2020;2:104-115. doi: 10.1016/j.crstbi.2020.05.001. Epub 2020 May 12. Curr Res Struct Biol. 2020. PMID: 33554132 Free PMC article.
84 results