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2021 4
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Page 1
Artificial intelligence for multimodal data integration in oncology.
Lipkova J, Chen RJ, Chen B, Lu MY, Barbieri M, Shao D, Vaidya AJ, Chen C, Zhuang L, Williamson DFK, Shaban M, Chen TY, Mahmood F. Lipkova J, et al. Cancer Cell. 2022 Oct 10;40(10):1095-1110. doi: 10.1016/j.ccell.2022.09.012. Cancer Cell. 2022. PMID: 36220072 Free PMC article. Review.
Transcription factors interact with RNA to regulate genes.
Oksuz O, Henninger JE, Warneford-Thomson R, Zheng MM, Erb H, Vancura A, Overholt KJ, Hawken SW, Banani SF, Lauman R, Reich LN, Robertson AL, Hannett NM, Lee TI, Zon LI, Bonasio R, Young RA. Oksuz O, et al. Mol Cell. 2023 Jul 20;83(14):2449-2463.e13. doi: 10.1016/j.molcel.2023.06.012. Epub 2023 Jul 3. Mol Cell. 2023. PMID: 37402367 Free PMC article.
A visual-language foundation model for computational pathology.
Lu MY, Chen B, Williamson DFK, Chen RJ, Liang I, Ding T, Jaume G, Odintsov I, Le LP, Gerber G, Parwani AV, Zhang A, Mahmood F. Lu MY, et al. Nat Med. 2024 Mar;30(3):863-874. doi: 10.1038/s41591-024-02856-4. Epub 2024 Mar 19. Nat Med. 2024. PMID: 38504017 Free PMC article.
Cancer cell plasticity and MHC-II-mediated immune tolerance promote breast cancer metastasis to lymph nodes.
Lei PJ, Pereira ER, Andersson P, Amoozgar Z, Van Wijnbergen JW, O'Melia MJ, Zhou H, Chatterjee S, Ho WW, Posada JM, Kumar AS, Morita S, Menzel L, Chung C, Ergin I, Jones D, Huang P, Beyaz S, Padera TP. Lei PJ, et al. J Exp Med. 2023 Sep 4;220(9):e20221847. doi: 10.1084/jem.20221847. Epub 2023 Jun 21. J Exp Med. 2023. PMID: 37341991 Free PMC article.
Towards a general-purpose foundation model for computational pathology.
Chen RJ, Ding T, Lu MY, Williamson DFK, Jaume G, Song AH, Chen B, Zhang A, Shao D, Shaban M, Williams M, Oldenburg L, Weishaupt LL, Wang JJ, Vaidya A, Le LP, Gerber G, Sahai S, Williams W, Mahmood F. Chen RJ, et al. Nat Med. 2024 Mar;30(3):850-862. doi: 10.1038/s41591-024-02857-3. Epub 2024 Mar 19. Nat Med. 2024. PMID: 38504018 Free PMC article.
UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
Tsai JM, Aguirre JD, Li YD, Brown J, Focht V, Kater L, Kempf G, Sandoval B, Schmitt S, Rutter JC, Galli P, Sandate CR, Cutler JA, Zou C, Donovan KA, Lumpkin RJ, Cavadini S, Park PMC, Sievers Q, Hatton C, Ener E, Regalado BD, Sperling MT, Słabicki M, Kim J, Zon R, Zhang Z, Miller PG, Belizaire R, Sperling AS, Fischer ES, Irizarry R, Armstrong SA, Thomä NH, Ebert BL. Tsai JM, et al. Mol Cell. 2023 Aug 3;83(15):2753-2767.e10. doi: 10.1016/j.molcel.2023.06.028. Epub 2023 Jul 20. Mol Cell. 2023. PMID: 37478846 Free PMC article.
Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes.
Schenkel JM, Herbst RH, Canner D, Li A, Hillman M, Shanahan SL, Gibbons G, Smith OC, Kim JY, Westcott P, Hwang WL, Freed-Pastor WA, Eng G, Cuoco MS, Rogers P, Park JK, Burger ML, Rozenblatt-Rosen O, Cong L, Pauken KE, Regev A, Jacks T. Schenkel JM, et al. Immunity. 2021 Oct 12;54(10):2338-2353.e6. doi: 10.1016/j.immuni.2021.08.026. Epub 2021 Sep 16. Immunity. 2021. PMID: 34534439 Free PMC article.
Analysis of 3D pathology samples using weakly supervised AI.
Song AH, Williams M, Williamson DFK, Chow SSL, Jaume G, Gao G, Zhang A, Chen B, Baras AS, Serafin R, Colling R, Downes MR, Farré X, Humphrey P, Verrill C, True LD, Parwani AV, Liu JTC, Mahmood F. Song AH, et al. Cell. 2024 May 9;187(10):2502-2520.e17. doi: 10.1016/j.cell.2024.03.035. Cell. 2024. PMID: 38729110
30 results