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PD-1 and LAG-3: synergistic fostering of T cell exhaustion.
Hofmann M, Thimme R, Schamel WW. Hofmann M, et al. Signal Transduct Target Ther. 2024 Oct 18;9(1):291. doi: 10.1038/s41392-024-02000-1. Signal Transduct Target Ther. 2024. PMID: 39424778 Free PMC article. No abstract available.
Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern.
Wratil PR, Stern M, Priller A, Willmann A, Almanzar G, Vogel E, Feuerherd M, Cheng CC, Yazici S, Christa C, Jeske S, Lupoli G, Vogt T, Albanese M, Mejías-Pérez E, Bauernfried S, Graf N, Mijocevic H, Vu M, Tinnefeld K, Wettengel J, Hoffmann D, Muenchhoff M, Daechert C, Mairhofer H, Krebs S, Fingerle V, Graf A, Steininger P, Blum H, Hornung V, Liebl B, Überla K, Prelog M, Knolle P, Keppler OT, Protzer U. Wratil PR, et al. Nat Med. 2022 Mar;28(3):496-503. doi: 10.1038/s41591-022-01715-4. Epub 2022 Jan 28. Nat Med. 2022. PMID: 35090165