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Page 1
Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder.
Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames T, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, Calabrese JR, Ødegaard KJ, McCarthy MJ, Zandi PP, Alda M, Nievergelt CM; Pharmacogenomics of Bipolar Disorder Study; Mi S, Brennand KJ, Kelsoe JR, Gage FH, Yao J. Mertens J, et al. Nature. 2015 Nov 5;527(7576):95-9. doi: 10.1038/nature15526. Epub 2015 Oct 28. Nature. 2015. PMID: 26524527 Free PMC article.
Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study.
Ou AH, Rosenthal SB, Adli M, Akiyama K, Akula N, Alda M, Amare AT, Ardau R, Arias B, Aubry JM, Backlund L, Bauer M, Baune BT, Bellivier F, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Cervantes P, Chen GB, Chen HC, Chillotti C, Cichon S, Clark SR, Colom F, Cousins DA, Cruceanu C, Czerski PM, Dantas CR, Dayer A, Del Zompo M, Degenhardt F, DePaulo JR, Étain B, Falkai P, Fellendorf FT, Ferensztajn-Rochowiak E, Forstner AJ, Frisén L, Frye MA, Fullerton JM, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Grof P, Gruber O, Hashimoto R, Hauser J, Heilbronner U, Herms S, Hoffmann P, Hofmann A, Hou L, Jamain S, Jiménez E, Kahn JP, Kassem L, Kato T, Kittel-Schneider S, König B, Kuo PH, Kusumi I, Lackner N, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, Jaramillo CAL, MacQueen G, Maj M, Manchia M, Marie-Claire C, Martinsson L, Mattheisen M, McCarthy MJ, McElroy SL, McMahon FJ, Mitchell PB, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nöthen MM, Novák T, Ösby U, Ozaki N, Papiol S, Perlis RH, Pisanu C, Potash JB, Pfennig A, Reich-Erkelenz D, Reif A, Reininghaus EZ, Rietschel M, Rouleau GA, Rybakowski JK, Schalling M, Schofield PR, Schubert KO, Schulze TG, Sch… See abstract for full author list ➔ Ou AH, et al. Transl Psychiatry. 2024 Feb 23;14(1):109. doi: 10.1038/s41398-024-02811-4. Transl Psychiatry. 2024. PMID: 38395906 Free PMC article.
Lithium Response in Bipolar Disorder is Associated with Focal Adhesion and PI3K-Akt Networks: A Multi-omics Replication Study.
Kelsoe J, Ou A, Rosenthal S, Adli M, Akiyama K, Akula N, Alda M, Amare AT, Ardau R, Arias B, Aubry JM, Backlund L, Banzato C, Bauer M, Baune B, Bellivier F, Benabarre A, Bengesser S, Abesh B, Biernacka J, Bui E, Cervantes P, Chen GB, Chen HC, Chillotti C, Cichon S, Clark S, Colom F, Cousins D, Cruceanu C, Czerski P, Dantas C, Dayer A, Degenhardt F, DePaulo JR, Etain B, Falkai P, Fellendorf F, Ferensztajn-Rochowiak E, Forstner AJ, Frisen L, Frye M, Fullerton J, Gard S, Garnham J, Goes F, Grigoroiu-Serbanescu M, Grof P, Gruber O, Hashimoto R, Hauser J, Heilbronner U, Herms S, Hoffmann P, Hofmann A, Hou L, Jamain S, Jiménez E, Kahn JP, Kassem L, Kato T, Kittel-Schneider S, König B, Kuo PH, Kusumi I, Dalkner N, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband S, Jaramillo CL, MacQueen G, Maj M, Manchia M, Marie-Claire C, Martinsson L, Mattheisen M, McCarthy M, McElroy S, McMahon F, Mitchell P, Mitjans M, Mondimore F, Monteleone P, Nievergelt C, Nöthen M, Novak T, Osby U, Ozaki N, Papiol S, Perlis R, Pfennig A, Potash J, Reich-Erkelenz D, Reif A, Reininghaus E, Rietschel M, Rouleau G, Rybakowski JK, Schalling M, Schofield P, Schubert KO, Schulze T, Schweizer B, Seemüller F, Severino … See abstract for full author list ➔ Kelsoe J, et al. Res Sq [Preprint]. 2023 Oct 3:rs.3.rs-3258813. doi: 10.21203/rs.3.rs-3258813/v1. Res Sq. 2023. Update in: Transl Psychiatry. 2024 Feb 23;14(1):109. doi: 10.1038/s41398-024-02811-4 PMID: 37886563 Free PMC article. Updated. Preprint.
Circadian rhythms in bipolar disorder patient-derived neurons predict lithium response: preliminary studies.
Mishra HK, Ying NM, Luis A, Wei H, Nguyen M, Nakhla T, Vandenburgh S, Alda M, Berrettini WH, Brennand KJ, Calabrese JR, Coryell WH, Frye MA, Gage FH, Gershon ES, McInnis MG, Nievergelt CM, Nurnberger JI, Shilling PD, Oedegaard KJ, Zandi PP; Pharmacogenomics of Bipolar Disorder Study; Kelsoe JR, Welsh DK, McCarthy MJ. Mishra HK, et al. Mol Psychiatry. 2021 Jul;26(7):3383-3394. doi: 10.1038/s41380-021-01048-7. Epub 2021 Mar 5. Mol Psychiatry. 2021. PMID: 33674753 Free PMC article.
Neuroimaging in psychiatric pharmacogenetics research: the promise and pitfalls.
Falcone M, Smith RM, Chenoweth MJ, Bhattacharjee AK, Kelsoe JR, Tyndale RF, Lerman C; Pharmacogenomics Research Network Central Nervous System Working Group. Falcone M, et al. Neuropsychopharmacology. 2013 Nov;38(12):2327-37. doi: 10.1038/npp.2013.152. Epub 2013 Jun 24. Neuropsychopharmacology. 2013. PMID: 23793356 Free PMC article. Review.
In vivo imaging of dendritic pruning in dentate granule cells.
Gonçalves JT, Bloyd CW, Shtrahman M, Johnston ST, Schafer ST, Parylak SL, Tran T, Chang T, Gage FH. Gonçalves JT, et al. Nat Neurosci. 2016 Jun;19(6):788-91. doi: 10.1038/nn.4301. Epub 2016 May 2. Nat Neurosci. 2016. PMID: 27135217 Free PMC article.
Neural progenitor cells derived from lithium responsive and non-responsive bipolar disorder patients exhibit distinct sensitivity to cell death following methamphetamine.
Mishra HK, Mandyam AD, Trenet W, Wei H, Nievergelt CM, Maihofer AX, Shilling PD, Alda M, Gershon E, McInnis MG; Pharmacogenomics of Bipolar Disorder Study; Kelsoe JR, McCarthy MJ. Mishra HK, et al. Neuropharmacology. 2023 Mar 15;226:109410. doi: 10.1016/j.neuropharm.2022.109410. Epub 2023 Jan 4. Neuropharmacology. 2023. PMID: 36608815
Clinical predictors of non-response to lithium treatment in the Pharmacogenomics of Bipolar Disorder (PGBD) study.
Lin Y, Maihofer AX, Stapp E, Ritchey M, Alliey-Rodriguez N, Anand A, Balaraman Y, Berrettini WH, Bertram H, Bhattacharjee A, Calkin CV, Conroy C, Coryell W, D'Arcangelo N, DeModena A, Biernacka JM, Fisher C, Frazier N, Frye M, Gao K, Garnham J, Gershon E, Glazer K, Goes FS, Goto T, Karberg E, Harrington G, Jakobsen P, Kamali M, Kelly M, Leckband SG, Lohoff FW, Stautland A, McCarthy MJ, McInnis MG, Mondimore F, Morken G, Nurnberger JI, Oedegaard KJ, Syrstad VEG, Ryan K, Schinagle M, Schoeyen H, Andreassen OA, Shaw M, Shilling PD, Slaney C, Tarwater B, Calabrese JR, Alda M, Nievergelt CM, Zandi PP, Kelsoe JR. Lin Y, et al. Bipolar Disord. 2021 Dec;23(8):821-831. doi: 10.1111/bdi.13078. Epub 2021 May 5. Bipolar Disord. 2021. PMID: 33797828 Clinical Trial.
Differential contributions of circadian clock genes to cell survival in bipolar disorder patient derived neuronal progenitor cells distinguishes lithium responders and non-responders.
Mishra HK, Wei H, LeRoux M, Ko I, Rohr KE, Nievergelt CM, Maihofer AX, Shilling P, Alda M, Berrettini WH, Calabrese JR, Coryell WH, Frye M, Gershon E, McInnis MG, Nurnberger J, Oedegaard KJ, Zandi PP, Kelsoe JR, McCarthy MJ. Mishra HK, et al. Res Sq [Preprint]. 2024 Apr 30:rs.3.rs-4331810. doi: 10.21203/rs.3.rs-4331810/v1. Res Sq. 2024. PMID: 38746315 Free PMC article. Preprint.
35 results