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Commensal microbiome promotes hair follicle regeneration by inducing keratinocyte HIF-1α signaling and glutamine metabolism.
Wang G, Sweren E, Andrews W, Li Y, Chen J, Xue Y, Wier E, Alphonse MP, Luo L, Miao Y, Chen R, Zeng D, Lee S, Li A, Dare E, Kim D, Archer NK, Reddy SK, Resar L, Hu Z, Grice EA, Kane MA, Garza LA. Wang G, et al. Sci Adv. 2023 Jan 4;9(1):eabo7555. doi: 10.1126/sciadv.abo7555. Epub 2023 Jan 4. Sci Adv. 2023. PMID: 36598999 Free PMC article.
Neutrophil extracellular traps impair regeneration.
Wier E, Asada M, Wang G, Alphonse MP, Li A, Hintelmann C, Sweren E, Youn C, Pielstick B, Ortines R, Lyu C, Daskam M, Miller LS, Archer NK, Garza LA. Wier E, et al. J Cell Mol Med. 2021 Nov;25(21):10008-10019. doi: 10.1111/jcmm.16896. Epub 2021 Oct 8. J Cell Mol Med. 2021. PMID: 34623736 Free PMC article.
The use of ectopic volar fibroblasts to modify skin identity.
Lee SS, Sweren E, Dare E, Derr P, Derr K, Wang CC, Hardesty B, Willis AA, Chen J, Vuillier JK, Du J, Wool J, Ruci A, Wang VY, Lee C, Iyengar S, Asami S, Daskam M, Lee C, Lee JC, Cho D, Kim J, Martinez-Peña EG, Lee SM, He X, Wakeman M, Sicilia I, Dobbs DT, van Ee A, Li A, Xue Y, Williams KL, Kirby CS, Kim D, Kim S, Xu L, Wang R, Ferrer M, Chen Y, Kang JU, Kalhor R, Kang S, Garza LA. Lee SS, et al. Science. 2024 Sep 6;385(6713):eadi1650. doi: 10.1126/science.adi1650. Epub 2024 Sep 6. Science. 2024. PMID: 39236183 Free PMC article.
Mechanical tension mobilizes Lgr6+ epidermal stem cells to drive skin growth.
Xue Y, Lyu C, Taylor A, Van Ee A, Kiemen A, Choi Y, Khavanian N, Henn D, Lee C, Hwang L, Wier E, Wang S, Lee S, Li A, Kirby C, Wang G, Wu PH, Wirtz D, Garza LA, Reddy SK. Xue Y, et al. Sci Adv. 2022 Apr 29;8(17):eabl8698. doi: 10.1126/sciadv.abl8698. Epub 2022 Apr 27. Sci Adv. 2022. PMID: 35476447 Free PMC article.
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