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Does gene deletion of AMPA GluA1 phenocopy features of schizoaffective disorder?
Fitzgerald PJ, Barkus C, Feyder M, Wiedholz LM, Chen YC, Karlsson RM, Machado-Vieira R, Graybeal C, Sharp T, Zarate C, Harvey-White J, Du J, Sprengel R, Gass P, Bannerman D, Holmes A. Fitzgerald PJ, et al. Neurobiol Dis. 2010 Dec;40(3):608-21. doi: 10.1016/j.nbd.2010.08.005. Epub 2010 Aug 8. Neurobiol Dis. 2010. PMID: 20699120 Free PMC article.
Strain differences in stress responsivity are associated with divergent amygdala gene expression and glutamate-mediated neuronal excitability.
Mozhui K, Karlsson RM, Kash TL, Ihne J, Norcross M, Patel S, Farrell MR, Hill EE, Graybeal C, Martin KP, Camp M, Fitzgerald PJ, Ciobanu DC, Sprengel R, Mishina M, Wellman CL, Winder DG, Williams RW, Holmes A. Mozhui K, et al. J Neurosci. 2010 Apr 14;30(15):5357-67. doi: 10.1523/JNEUROSCI.5017-09.2010. J Neurosci. 2010. PMID: 20392957 Free PMC article.
Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning.
Brigman JL, Wright T, Talani G, Prasad-Mulcare S, Jinde S, Seabold GK, Mathur P, Davis MI, Bock R, Gustin RM, Colbran RJ, Alvarez VA, Nakazawa K, Delpire E, Lovinger DM, Holmes A. Brigman JL, et al. J Neurosci. 2010 Mar 31;30(13):4590-600. doi: 10.1523/JNEUROSCI.0640-10.2010. J Neurosci. 2010. PMID: 20357110 Free PMC article.