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APOε4 is associated with enhanced in vivo innate immune responses in human subjects.
Gale SC, Gao L, Mikacenic C, Coyle SM, Rafaels N, Murray Dudenkov T, Madenspacher JH, Draper DW, Ge W, Aloor JJ, Azzam KM, Lai L, Blackshear PJ, Calvano SE, Barnes KC, Lowry SF, Corbett S, Wurfel MM, Fessler MB. Gale SC, et al. J Allergy Clin Immunol. 2014 Jul;134(1):127-34. doi: 10.1016/j.jaci.2014.01.032. Epub 2014 Mar 18. J Allergy Clin Immunol. 2014. PMID: 24655576 Free PMC article.