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Specific Mutations in the Cholesterol-Binding Site of APP Alter Its Processing and Favor the Production of Shorter, Less Toxic Aβ Peptides.
Hanbouch L, Schaack B, Kasri A, Fontaine G, Gkanatsiou E, Brinkmalm G, Camporesi E, Portelius E, Blennow K, Mourier G, Gilles N, Millan MJ, Marquer C, Zetterberg H, Boussicault L, Potier MC. Hanbouch L, et al. Mol Neurobiol. 2022 Nov;59(11):7056-7073. doi: 10.1007/s12035-022-03025-9. Epub 2022 Sep 9. Mol Neurobiol. 2022. PMID: 36076005 Free PMC article.