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Page 1
Laparoscopic ileocaecal resection versus infliximab for terminal ileitis in Crohn's disease: a randomised controlled, open-label, multicentre trial.
Ponsioen CY, de Groof EJ, Eshuis EJ, Gardenbroek TJ, Bossuyt PMM, Hart A, Warusavitarne J, Buskens CJ, van Bodegraven AA, Brink MA, Consten ECJ, van Wagensveld BA, Rijk MCM, Crolla RMPH, Noomen CG, Houdijk APJ, Mallant RC, Boom M, Marsman WA, Stockmann HB, Mol B, de Groof AJ, Stokkers PC, D'Haens GR, Bemelman WA; LIR!C study group. Ponsioen CY, et al. Lancet Gastroenterol Hepatol. 2017 Nov;2(11):785-792. doi: 10.1016/S2468-1253(17)30248-0. Epub 2017 Aug 31. Lancet Gastroenterol Hepatol. 2017. PMID: 28838644 Clinical Trial.
Patients with diseased terminal ileum longer than 40 cm or abdominal abscesses were excluded. The primary outcome was quality of life on the Inflammatory Bowel Disease Questionnaire (IBDQ) at 12 months. Secondary outcomes were general quality of life, measured by th …
Patients with diseased terminal ileum longer than 40 cm or abdominal abscesses were excluded. The primary outcome was quality of life
Sleep and sleep disorders during pregnancy and postpartum: The Life-ON study.
Manconi M, van der Gaag LC, Mangili F, Garbazza C, Riccardi S, Cajochen C, Mondini S, Furia F, Zambrelli E, Baiardi S, Giordano A, Rizzo N, Fonti C, Viora E, D'Agostino A, Cicolin A, Cirignotta F; Life-ON Study Group; Group of Milan (Italy); Aquilino D, Barassi A, Del Giudice R, Fior G, Gambini O, Giordano B, Martini A, Serrati C, Stefanelli R, Scarone S, Canevini M, Fanti V, Stein HC, Marconi AM; Group of Turin (Italy); Raimondo E, Viglietta E; Group of Bologna (Italy); Santoro R, Simonazzi G, Bianconcini A; Group of Lugano (Switzerland); Meani F, Piazza N, Filippakos F, Gyr T. Manconi M, et al. Sleep Med. 2024 Jan;113:41-48. doi: 10.1016/j.sleep.2023.10.021. Epub 2023 Nov 11. Sleep Med. 2024. PMID: 37984016
OBJECTIVE: to prospectively assess sleep and sleep disorders during pregnancy and postpartum in a large cohort of women. METHODS: multicenter prospective Life-ON study, recruiting consecutive pregnant women at a gestational age between 10 and 15 weeks, from the loca …
OBJECTIVE: to prospectively assess sleep and sleep disorders during pregnancy and postpartum in a large cohort of women. METHODS: multicente …
A machine learning model to predict the risk of perinatal depression: Psychosocial and sleep-related factors in the Life-ON study cohort.
Garbazza C, Mangili F, D'Onofrio TA, Malpetti D, Riccardi S, Cicolin A, D'Agostino A, Cirignotta F, Manconi M; “Life-ON” study group. Garbazza C, et al. Psychiatry Res. 2024 Jul;337:115957. doi: 10.1016/j.psychres.2024.115957. Epub 2024 May 23. Psychiatry Res. 2024. PMID: 38788556 Free article.
We applied a machine learning (ML) approach to data from a multicenter cohort study on sleep and mood changes during the perinatal period ("Life-ON") to derive models for PND risk prediction in a cross-validation setting. A wide range of sociodemographic variables, …
We applied a machine learning (ML) approach to data from a multicenter cohort study on sleep and mood changes during the perinatal period (" …
Influence of chronotype on the incidence and severity of perinatal depression in the "Life-ON" study.
Garbazza C, Hackethal S, Migliore E, D'Agostino A, Serrati C, Fanti V, Riccardi S, Baiardi S, Cicolin A, Borgwardt S, Mondini S, Cirignotta F, Cajochen C, Manconi M; “Life-ON” study group. Garbazza C, et al. J Affect Disord. 2022 Nov 15;317:245-255. doi: 10.1016/j.jad.2022.08.064. Epub 2022 Aug 31. J Affect Disord. 2022. PMID: 36055526 Free article.
Heterogeneity in the half-life of factor VIII concentrate in patients with hemophilia A is due to variability in the clearance of endogenous von Willebrand factor.
Elsheikh E, Lavin M, Heck LA, Larkin N, Mullaney B, Doherty D, Kennedy M, Keenan C, Guest T, O'Mahony B, Fazavana J, Fallon PG, Preston RJS, Gormley J, Ryan K, O'Connell NM, Singleton E, Byrne M, McGowan M, Roche S, Doyle M, Crowley MP, O'Shea SI, Reipert BM, Johnsen JM, Pipe SW, Di Paola J, Turecek PL, O'Donnell JS; iPATH study group. Elsheikh E, et al. J Thromb Haemost. 2023 May;21(5):1123-1134. doi: 10.1016/j.jtha.2023.01.013. Epub 2023 Jan 20. J Thromb Haemost. 2023. PMID: 36775768 Free article.
Finally, the effects of variation in FVIII half-life on clinical phenotype were investigated. RESULTS: We demonstrated that heterogeneity in the clearance of endogenous plasma VWF is a key determinant of variable FVIII half-life in PWH. ...
Finally, the effects of variation in FVIII half-life on clinical phenotype were investigated. RESULTS: We demonstrated that he …
Impact of the iWHELD digital person-centered care program on quality of life, agitation and psychotropic medications in people with dementia living in nursing homes during the COVID-19 pandemic: A randomized controlled trial.
McDermid J, Henley W, Corbett A, Williams G, Fossey J, Clare L, Fox C, Aarsland D, Khan Z, Soto M, Woodward-Carlton B, Cook EM, Cummings J, Sweetnam A, Chan X, Lawrence M, Ballard C; iWHELD study group. McDermid J, et al. Alzheimers Dement. 2024 Mar;20(3):1797-1806. doi: 10.1002/alz.13582. Epub 2023 Dec 20. Alzheimers Dement. 2024. PMID: 38116916 Free PMC article. Clinical Trial.
RESULTS: iWHELD conferred benefit to quality of life on the primary (F = 4.3, p = 0.04) and secondary measures of quality of life (F = 6.45, p = 0.01) and reduced psychotropic medication use (chi(2) = 4.08, p = 0.04) with no worsening of agitation. ...
RESULTS: iWHELD conferred benefit to quality of life on the primary (F = 4.3, p = 0.04) and secondary measures of quality of l …
Implications of coagulation factor VIII and IX pharmacokinetics in the prophylactic treatment of haemophilia.
Collins PW, Fischer K, Morfini M, Blanchette VS, Björkman S; International Prophylaxis Study Group Pharmacokinetics Expert Working Group. Collins PW, et al. Haemophilia. 2011 Jan;17(1):2-10. doi: 10.1111/j.1365-2516.2010.02370.x. Epub 2010 Aug 22. Haemophilia. 2011. PMID: 20731726 Review.
Calculations suggest that adults need less FVIII per kg body weight than children. The effect of half-life on trough levels questions the logic of Monday, Wednesday, Friday dosing and suggests a role for innovative regimens including low-dose daily treatment which l …
Calculations suggest that adults need less FVIII per kg body weight than children. The effect of half-life on trough levels qu …
Trends in use of prostacyclin analogs for management of CDH-associated pulmonary hypertension.
Ramaraj AB, Rice-Townsend SE, Foster CL, Yung D, Jackson EO, Ebanks AH, Stark RA; Congenital Diaphragmatic Hernia Study Group. Ramaraj AB, et al. Pediatr Surg Int. 2022 Sep;38(9):1241-1247. doi: 10.1007/s00383-022-05176-1. Epub 2022 Jul 16. Pediatr Surg Int. 2022. PMID: 35841395
Records were reviewed to describe the number of patients receiving prostacyclins, the day of life on which the agent was started, start time relative to ECLS, the duration of medication use, and continuation of the medication at the time of discharge. ...
Records were reviewed to describe the number of patients receiving prostacyclins, the day of life on which the agent was start …
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