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Lupus anticoagulant associates with thrombosis in patients with COVID-19 admitted to intensive care units: A retrospective cohort study.
Noordermeer T, Schutgens REG, Visser C, Rademaker E, de Maat MPM, Jansen AJG, Limper M, Cremer OL, Kruip MJHA, Endeman H, Maas C, de Laat B, Urbanus RT; Dutch COVID & Thrombosis Coalition (DCTC). Noordermeer T, et al. Res Pract Thromb Haemost. 2022 Sep 16;6(6):e12809. doi: 10.1002/rth2.12809. eCollection 2022 Aug. Res Pract Thromb Haemost. 2022. PMID: 36178455 Free PMC article.
BACKGROUND: Thrombosis is a frequent and severe complication in patients with coronavirus disease 2019 (COVID-19) admitted to the intensive care unit (ICU). Lupus anticoagulant (LA) is a strong acquired risk factor for thrombosis in various diseases and is frequentl …
BACKGROUND: Thrombosis is a frequent and severe complication in patients with coronavirus disease 2019 (COVID-19) admitted to …
Absence of COVID-19-associated changes in plasma coagulation proteins and pulmonary thrombosis in the ferret model.
Kreft IC, Winiarczyk RRA, Tanis FJ, van der Zwaan C, Schmitz KS, Hoogendijk AJ, de Swart RL, Moscona A, Porotto M, Salvatori DCF, de Vries RD, de Maat MPM, van den Biggelaar M, van Vlijmen BJM; Dutch Covid-19 and Thrombosis Coalition (DCTC). Kreft IC, et al. Thromb Res. 2022 Feb;210:6-11. doi: 10.1016/j.thromres.2021.12.015. Epub 2021 Dec 21. Thromb Res. 2022. PMID: 34954402 Free PMC article.
Studies on the exact mechanism(s) underlying thrombosis in COVID-19 are limited as animal models commonly used to study venous thrombosis pathophysiology (i.e. rats and mice) are naturally not susceptible to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS …
Studies on the exact mechanism(s) underlying thrombosis in COVID-19 are limited as animal models commonly used to study venous …
Risk of thrombotic complications in influenza versus COVID-19 hospitalized patients.
Stals MAM, Grootenboers MJJH, van Guldener C, Kaptein FHJ, Braken SJE, Chen Q, Chu G, van Driel EM, Iglesias Del Sol A, de Jonge E, Kant KM, Pals F, Toorop MMA, Cannegieter SC, Klok FA, Huisman MV; Dutch COVID & Thrombosis Coalition (DCTC). Stals MAM, et al. Res Pract Thromb Haemost. 2021 Apr 8;5(3):412-420. doi: 10.1002/rth2.12496. eCollection 2021 Mar. Res Pract Thromb Haemost. 2021. PMID: 33821230 Free PMC article.
In parallel, we assessed the cumulative incidence of thrombotic complications-adjusted for competing risk of death-in patients with COVID-19 in three Dutch hospitals (February 24 to April 26, 2020). RESULTS: Of the 13 217 hospitalized patients with influenza, …
In parallel, we assessed the cumulative incidence of thrombotic complications-adjusted for competing risk of death-in patients with COVID …
Suggestions for global coagulation assays for the assessment of COVID-19 associated hypercoagulability.
van de Berg TW, Hulshof AM, Nagy M, van Oerle R, Sels JW, van Bussel B, Ten Cate H, Henskens Y, Spronk HMH; Dutch Covid-19 and Thrombosis Coalition (DCTC). van de Berg TW, et al. Thromb Res. 2021 May;201:84-89. doi: 10.1016/j.thromres.2021.02.026. Epub 2021 Feb 24. Thromb Res. 2021. PMID: 33662799 Free PMC article.
Global coagulation assays like thrombin generation (TG) and rotational thromboelastometry (ROTEM) might be suitable in estimating COVID-19 associated coagulopathy and thrombosis risk. Therefore, we aimed at validating both assays for samples with high levels of fibr …
Global coagulation assays like thrombin generation (TG) and rotational thromboelastometry (ROTEM) might be suitable in estimating COVID …
Ruling out Pulmonary Embolism in Patients with (Suspected) COVID-19-A Prospective Cohort Study.
Stals MAM, Kaptein FHJ, Bemelmans RHH, van Bemmel T, Boukema IC, Braeken DCW, Braken SJE, Bresser C, Cate HT, Deenstra DD, Dooren YPAV, Faber LM, Grootenboers MJJH, Haan LR, Haazer C, Sol AID, Kelliher S, Koster T, Kroft LJM, Meijer RI, Pals F, van Thiel ERE, Westerweel PE, Wolde MT, Klok FA, Huisman MV; Dutch COVID & Thrombosis Coalition (DCTC). Stals MAM, et al. TH Open. 2021 Sep 15;5(3):e387-e399. doi: 10.1055/s-0041-1735155. eCollection 2021 Jul. TH Open. 2021. PMID: 34541450 Free PMC article.
Background Diagnostic strategies for suspected pulmonary embolism (PE) have not been prospectively evaluated in COVID-19 patients. Methods Prospective, multicenter, outcome study in 707 patients with both (suspected) COVID-19 and suspected PE in 14 hos …
Background Diagnostic strategies for suspected pulmonary embolism (PE) have not been prospectively evaluated in COVID-19 patie …