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Page 1
Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial.
Lavine JE, Schwimmer JB, Van Natta ML, Molleston JP, Murray KF, Rosenthal P, Abrams SH, Scheimann AO, Sanyal AJ, Chalasani N, Tonascia J, Ünalp A, Clark JM, Brunt EM, Kleiner DE, Hoofnagle JH, Robuck PR; Nonalcoholic Steatohepatitis Clinical Research Network. Lavine JE, et al. JAMA. 2011 Apr 27;305(16):1659-68. doi: 10.1001/jama.2011.520. JAMA. 2011. PMID: 21521847 Free PMC article. Clinical Trial.
Treatment of nonalcoholic fatty liver disease in children: TONIC trial design.
Lavine JE, Schwimmer JB, Molleston JP, Scheimann AO, Murray KF, Abrams SH, Rosenthal P, Sanyal AJ, Robuck PR, Brunt EM, Unalp A, Tonascia J; Nonalcoholic Steatohepatitis Clinical Research Network Research Group. Lavine JE, et al. Contemp Clin Trials. 2010 Jan;31(1):62-70. doi: 10.1016/j.cct.2009.09.001. Epub 2009 Sep 15. Contemp Clin Trials. 2010. PMID: 19761871 Free PMC article. Clinical Trial.
Improvement in liver histology is associated with reduction in dyslipidemia in children with nonalcoholic fatty liver disease.
Corey KE, Vuppalanchi R, Vos M, Kohli R, Molleston JP, Wilson L, Unalp-Arida A, Cummings OW, Lavine JE, Chalasani N; Nonalcoholic Steatohepatitis Clinical Research Network. Corey KE, et al. J Pediatr Gastroenterol Nutr. 2015 Mar;60(3):360-7. doi: 10.1097/MPG.0000000000000584. J Pediatr Gastroenterol Nutr. 2015. PMID: 25714579 Free PMC article. Clinical Trial.