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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 2
1976 1
1991 1
1992 3
1993 4
1994 1
1995 1
1996 2
1997 4
1998 1
1999 1
2000 1
2004 1
2005 2
2006 2
2007 3
2008 1
2009 3
2010 2
2011 1
2012 1
2018 1
2022 2
2024 2
2025 0

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40 results

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Page 1
Emraclidine, a novel positive allosteric modulator of cholinergic M4 receptors, for the treatment of schizophrenia: a two-part, randomised, double-blind, placebo-controlled, phase 1b trial.
Krystal JH, Kane JM, Correll CU, Walling DP, Leoni M, Duvvuri S, Patel S, Chang I, Iredale P, Frohlich L, Versavel S, Perry P, Sanchez R, Renger J. Krystal JH, et al. Among authors: iredale p. Lancet. 2022 Dec 17;400(10369):2210-2220. doi: 10.1016/S0140-6736(22)01990-0. Lancet. 2022. PMID: 36528376 Clinical Trial.
PET imaging of M4 muscarinic acetylcholine receptors in rhesus macaques using [11C]MK-6884: Quantification with kinetic modeling and receptor occupancy by CVL-231 (emraclidine), a novel positive allosteric modulator.
Belov V, Guehl NJ, Duvvuri S, Iredale P, Moon SH, Dhaynaut M, Chakilam S, MacDonagh AC, Rice PA, Yokell DL, Renger JJ, El Fakhri G, Normandin MD. Belov V, et al. Among authors: iredale p. J Cereb Blood Flow Metab. 2024 Aug;44(8):1329-1342. doi: 10.1177/0271678X241238820. Epub 2024 Mar 13. J Cereb Blood Flow Metab. 2024. PMID: 38477292
PET mapping of receptor occupancy using joint direct parametric reconstruction.
Marin T, Belov V, Chemli Y, Ouyang J, Najmaoui Y, Fakhri GE, Duvvuri S, Iredale P, Guehl NJ, Normandin MD, Petibon Y. Marin T, et al. Among authors: iredale p. IEEE Trans Biomed Eng. 2024 Oct 24;PP. doi: 10.1109/TBME.2024.3486191. Online ahead of print. IEEE Trans Biomed Eng. 2024. PMID: 39446540
Discovery of two clinical histamine H(3) receptor antagonists: trans-N-ethyl-3-fluoro-3-[3-fluoro-4-(pyrrolidinylmethyl)phenyl]cyclobutanecarboxamide (PF-03654746) and trans-3-fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]-N-(2-methylpropyl)cyclobutanecarboxamide (PF-03654764).
Wager TT, Pettersen BA, Schmidt AW, Spracklin DK, Mente S, Butler TW, Howard H, Lettiere DJ, Rubitski DM, Wong DF, Nedza FM, Nelson FR, Rollema H, Raggon JW, Aubrecht J, Freeman JK, Marcek JM, Cianfrogna J, Cook KW, James LC, Chatman LA, Iredale PA, Banker MJ, Homiski ML, Munzner JB, Chandrasekaran RY. Wager TT, et al. Among authors: iredale pa. J Med Chem. 2011 Nov 10;54(21):7602-20. doi: 10.1021/jm200939b. Epub 2011 Oct 7. J Med Chem. 2011. PMID: 21928839
Multiple malignant melanoma.
Iredale P. Iredale P. Nurs Times. 1974 Oct 17;70(42):1610-3. Nurs Times. 1974. PMID: 4438091 No abstract available.
New bicyclic cannabinoid receptor-1 (CB1-R) antagonists.
Carpino PA, Griffith DA, Sakya S, Dow RL, Black SC, Hadcock JR, Iredale PA, Scott DO, Fichtner MW, Rose CR, Day R, Dibrino J, Butler M, Debartolo DB, Dutcher D, Gautreau D, Lizano JS, O'connor RE, Sands MA, Kelly-Sullivan D, Ward KM. Carpino PA, et al. Among authors: iredale pa. Bioorg Med Chem Lett. 2006 Feb;16(3):731-6. doi: 10.1016/j.bmcl.2005.10.019. Epub 2005 Nov 2. Bioorg Med Chem Lett. 2006. PMID: 16263283
The Parkinson's progression markers initiative (PPMI) - establishing a PD biomarker cohort.
Marek K, Chowdhury S, Siderowf A, Lasch S, Coffey CS, Caspell-Garcia C, Simuni T, Jennings D, Tanner CM, Trojanowski JQ, Shaw LM, Seibyl J, Schuff N, Singleton A, Kieburtz K, Toga AW, Mollenhauer B, Galasko D, Chahine LM, Weintraub D, Foroud T, Tosun-Turgut D, Poston K, Arnedo V, Frasier M, Sherer T; Parkinson's Progression Markers Initiative. Marek K, et al. Ann Clin Transl Neurol. 2018 Oct 31;5(12):1460-1477. doi: 10.1002/acn3.644. eCollection 2018 Dec. Ann Clin Transl Neurol. 2018. PMID: 30564614 Free PMC article.
40 results