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49 results

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Page 1
A conserved dendritic-cell regulatory program limits antitumour immunity.
Maier B, Leader AM, Chen ST, Tung N, Chang C, LeBerichel J, Chudnovskiy A, Maskey S, Walker L, Finnigan JP, Kirkling ME, Reizis B, Ghosh S, D'Amore NR, Bhardwaj N, Rothlin CV, Wolf A, Flores R, Marron T, Rahman AH, Kenigsberg E, Brown BD, Merad M. Maier B, et al. Among authors: kenigsberg e. Nature. 2020 Apr;580(7802):257-262. doi: 10.1038/s41586-020-2134-y. Epub 2020 Mar 25. Nature. 2020. PMID: 32269339 Free PMC article.
Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy.
Martin JC, Chang C, Boschetti G, Ungaro R, Giri M, Grout JA, Gettler K, Chuang LS, Nayar S, Greenstein AJ, Dubinsky M, Walker L, Leader A, Fine JS, Whitehurst CE, Mbow ML, Kugathasan S, Denson LA, Hyams JS, Friedman JR, Desai PT, Ko HM, Laface I, Akturk G, Schadt EE, Salmon H, Gnjatic S, Rahman AH, Merad M, Cho JH, Kenigsberg E. Martin JC, et al. Among authors: kenigsberg e. Cell. 2019 Sep 5;178(6):1493-1508.e20. doi: 10.1016/j.cell.2019.08.008. Epub 2019 Aug 29. Cell. 2019. PMID: 31474370 Free PMC article.
Intratumoral dendritic cell-CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma.
Magen A, Hamon P, Fiaschi N, Soong BY, Park MD, Mattiuz R, Humblin E, Troncoso L, D'souza D, Dawson T, Kim J, Hamel S, Buckup M, Chang C, Tabachnikova A, Schwartz H, Malissen N, Lavin Y, Soares-Schanoski A, Giotti B, Hegde S, Ioannou G, Gonzalez-Kozlova E, Hennequin C, Le Berichel J, Zhao Z, Ward SC, Fiel I, Kou B, Dobosz M, Li L, Adler C, Ni M, Wei Y, Wang W, Atwal GS, Kundu K, Cygan KJ, Tsankov AM, Rahman A, Price C, Fernandez N, He J, Gupta NT, Kim-Schulze S, Gnjatic S, Kenigsberg E, Deering RP, Schwartz M, Marron TU, Thurston G, Kamphorst AO, Merad M. Magen A, et al. Among authors: kenigsberg e. Nat Med. 2023 Jun;29(6):1389-1399. doi: 10.1038/s41591-023-02345-0. Epub 2023 Jun 15. Nat Med. 2023. PMID: 37322116 Free PMC article.
Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification.
Leader AM, Grout JA, Maier BB, Nabet BY, Park MD, Tabachnikova A, Chang C, Walker L, Lansky A, Le Berichel J, Troncoso L, Malissen N, Davila M, Martin JC, Magri G, Tuballes K, Zhao Z, Petralia F, Samstein R, D'Amore NR, Thurston G, Kamphorst AO, Wolf A, Flores R, Wang P, Müller S, Mellman I, Beasley MB, Salmon H, Rahman AH, Marron TU, Kenigsberg E, Merad M. Leader AM, et al. Among authors: kenigsberg e. Cancer Cell. 2021 Dec 13;39(12):1594-1609.e12. doi: 10.1016/j.ccell.2021.10.009. Epub 2021 Nov 11. Cancer Cell. 2021. PMID: 34767762 Free PMC article.
Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells.
Casanova-Acebes M, Dalla E, Leader AM, LeBerichel J, Nikolic J, Morales BM, Brown M, Chang C, Troncoso L, Chen ST, Sastre-Perona A, Park MD, Tabachnikova A, Dhainaut M, Hamon P, Maier B, Sawai CM, Agulló-Pascual E, Schober M, Brown BD, Reizis B, Marron T, Kenigsberg E, Moussion C, Benaroch P, Aguirre-Ghiso JA, Merad M. Casanova-Acebes M, et al. Among authors: kenigsberg e. Nature. 2021 Jul;595(7868):578-584. doi: 10.1038/s41586-021-03651-8. Epub 2021 Jun 16. Nature. 2021. PMID: 34135508 Free PMC article.
Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease.
Lee JY, Hall JA, Kroehling L, Wu L, Najar T, Nguyen HH, Lin WY, Yeung ST, Silva HM, Li D, Hine A, Loke P, Hudesman D, Martin JC, Kenigsberg E, Merad M, Khanna KM, Littman DR. Lee JY, et al. Among authors: kenigsberg e. Cell. 2020 Jan 9;180(1):79-91.e16. doi: 10.1016/j.cell.2019.11.026. Epub 2019 Dec 19. Cell. 2020. PMID: 31866067 Free PMC article.
TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer.
Park MD, Reyes-Torres I, LeBerichel J, Hamon P, LaMarche NM, Hegde S, Belabed M, Troncoso L, Grout JA, Magen A, Humblin E, Nair A, Molgora M, Hou J, Newman JH, Farkas AM, Leader AM, Dawson T, D'Souza D, Hamel S, Sanchez-Paulete AR, Maier B, Bhardwaj N, Martin JC, Kamphorst AO, Kenigsberg E, Casanova-Acebes M, Horowitz A, Brown BD, De Andrade LF, Colonna M, Marron TU, Merad M. Park MD, et al. Among authors: kenigsberg e. Nat Immunol. 2023 May;24(5):792-801. doi: 10.1038/s41590-023-01475-4. Epub 2023 Apr 20. Nat Immunol. 2023. PMID: 37081148 Free PMC article.
Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity.
Uzzan M, Martin JC, Mesin L, Livanos AE, Castro-Dopico T, Huang R, Petralia F, Magri G, Kumar S, Zhao Q, Rosenstein AK, Tokuyama M, Sharma K, Ungaro R, Kosoy R, Jha D, Fischer J, Singh H, Keir ME, Ramamoorthi N, O'Gorman WE, Cohen BL, Rahman A, Cossarini F, Seki A, Leyre L, Vaquero ST, Gurunathan S, Grasset EK, Losic B, Dubinsky M, Greenstein AJ, Gottlieb Z, Legnani P, George J, Irizar H, Stojmirovic A, Brodmerkel C, Kasarkis A, Sands BE, Furtado G, Lira SA, Tuong ZK, Ko HM, Cerutti A, Elson CO, Clatworthy MR, Merad M, Suárez-Fariñas M, Argmann C, Hackney JA, Victora GD, Randolph GJ, Kenigsberg E, Colombel JF, Mehandru S. Uzzan M, et al. Among authors: kenigsberg e. Nat Med. 2022 Apr;28(4):766-779. doi: 10.1038/s41591-022-01680-y. Epub 2022 Feb 21. Nat Med. 2022. PMID: 35190725 Free PMC article.
Spatial Positioning and Matrix Programs of Cancer-Associated Fibroblasts Promote T-cell Exclusion in Human Lung Tumors.
Grout JA, Sirven P, Leader AM, Maskey S, Hector E, Puisieux I, Steffan F, Cheng E, Tung N, Maurin M, Vaineau R, Karpf L, Plaud M, Begue AL, Ganesh K, Mesple J, Casanova-Acebes M, Tabachnikova A, Keerthivasan S, Lansky A, Berichel JL, Walker L, Rahman AH, Gnjatic S, Girard N, Lefevre M, Damotte D, Adam J, Martin JC, Wolf A, Flores RM, Beasley MB, Pradhan R, Muller S, Marron TU, Turley SJ, Merad M, Kenigsberg E, Salmon H. Grout JA, et al. Among authors: kenigsberg e. Cancer Discov. 2022 Nov 2;12(11):2606-2625. doi: 10.1158/2159-8290.CD-21-1714. Cancer Discov. 2022. PMID: 36027053 Free PMC article.
Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors.
Paul F, Arkin Y, Giladi A, Jaitin DA, Kenigsberg E, Keren-Shaul H, Winter D, Lara-Astiaso D, Gury M, Weiner A, David E, Cohen N, Lauridsen FK, Haas S, Schlitzer A, Mildner A, Ginhoux F, Jung S, Trumpp A, Porse BT, Tanay A, Amit I. Paul F, et al. Among authors: kenigsberg e. Cell. 2015 Dec 17;163(7):1663-77. doi: 10.1016/j.cell.2015.11.013. Epub 2015 Nov 25. Cell. 2015. PMID: 26627738 Free article.
49 results