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18 results

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Page 1
A multicenter, randomized, placebo-controlled, double-blind phase 3 trial with open-arm comparison indicates safety and efficacy of nephroprotective therapy with ramipril in children with Alport's syndrome.
Gross O, Tönshoff B, Weber LT, Pape L, Latta K, Fehrenbach H, Lange-Sperandio B, Zappel H, Hoyer P, Staude H, König S, John U, Gellermann J, Hoppe B, Galiano M, Hoecker B, Ehren R, Lerch C, Kashtan CE, Harden M, Boeckhaus J, Friede T; German Pediatric Nephrology (GPN) Study Group and EARLY PRO-TECT Alport Investigators. Gross O, et al. Kidney Int. 2020 Jun;97(6):1275-1286. doi: 10.1016/j.kint.2019.12.015. Epub 2020 Jan 17. Kidney Int. 2020. PMID: 32299679 Free article. Clinical Trial.
Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy.
Kettwig M, Ternka K, Wendland K, Krüger DM, Zampar S, Schob C, Franz J, Aich A, Winkler A, Sakib MS, Kaurani L, Epple R, Werner HB, Hakroush S, Kitz J, Prinz M, Bartok E, Hartmann G, Schröder S, Rehling P, Henneke M, Boretius S, Alia A, Wirths O, Fischer A, Stadelmann C, Nessler S, Gärtner J. Kettwig M, et al. Nat Commun. 2021 Nov 11;12(1):6530. doi: 10.1038/s41467-021-26880-x. Nat Commun. 2021. PMID: 34764281 Free PMC article.
Drug screening identifies tazarotene and bexarotene as therapeutic agents in multiple sulfatase deficiency.
Schlotawa L, Tyka K, Kettwig M, Ahrens-Nicklas RC, Baud M, Berulava T, Brunetti-Pierri N, Gagne A, Herbst ZM, Maguire JA, Monfregola J, Pena T, Radhakrishnan K, Schröder S, Waxman EA, Ballabio A, Dierks T, Fischer A, French DL, Gelb MH, Gärtner J. Schlotawa L, et al. Among authors: kettwig m. EMBO Mol Med. 2023 Mar 8;15(3):e14837. doi: 10.15252/emmm.202114837. Epub 2023 Feb 15. EMBO Mol Med. 2023. PMID: 36789546 Free PMC article.
Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients.
Koll CEM, Hopff SM, Meurers T, Lee CH, Kohls M, Stellbrink C, Thibeault C, Reinke L, Steinbrecher S, Schreiber S, Mitrov L, Frank S, Miljukov O, Erber J, Hellmuth JC, Reese JP, Steinbeis F, Bahmer T, Hagen M, Meybohm P, Hansch S, Vadász I, Krist L, Jiru-Hillmann S, Prasser F, Vehreschild JJ; NAPKON Study Group. Koll CEM, et al. Sci Data. 2022 Dec 21;9(1):776. doi: 10.1038/s41597-022-01669-9. Sci Data. 2022. PMID: 36543828 Free PMC article.
Mesenchymal Hamartoma of the Liver and DICER1 Syndrome.
Apellaniz-Ruiz M, Segni M, Kettwig M, Glüer S, Pelletier D, Nguyen VH, Wagener R, López C, Muchantef K, Bouron-Dal Soglio D, Sabbaghian N, Wu MK, Zannella S, Fabian MR, Siebert R, Menke J, Priest JR, Foulkes WD. Apellaniz-Ruiz M, et al. Among authors: kettwig m. N Engl J Med. 2019 May 9;380(19):1834-1842. doi: 10.1056/NEJMoa1812169. N Engl J Med. 2019. PMID: 31067372
18 results