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Genetic characterization of multiple hepatitis C virus infections following acute infection in HIV-infected men who have sex with men.
Thomas XV, Grady BP, Van Der Meer JT, Ho CK, Vanhommerig JW, Rebers SP, De Jong MD, Van Der Valk M, Prins M, Molenkamp R, Schinkel J; MOSAIC (MSM Observational Study of Acute Infection with hepatitis C) study group. Thomas XV, et al. AIDS. 2015 Nov;29(17):2287-95. doi: 10.1097/QAD.0000000000000838. AIDS. 2015. PMID: 26258527
OBJECTIVE: High rates of hepatitis C virus (HCV) reinfections among HIV-infected men who have sex with men (MSM) following clearance of a primary infection suggest absence of protective immunity. Here, we investigated the incidence of HCV super and reinfections in 85 HIV-i …
OBJECTIVE: High rates of hepatitis C virus (HCV) reinfections among HIV-infected men who have sex with men (MSM) following clearance …
Alarming incidence of hepatitis C virus re-infection after treatment of sexually acquired acute hepatitis C virus infection in HIV-infected MSM.
Lambers FA, Prins M, Thomas X, Molenkamp R, Kwa D, Brinkman K, van der Meer JT, Schinkel J; MOSAIC (MSM Observational Study of Acute Infection with hepatitis C) study group. Lambers FA, et al. AIDS. 2011 Nov 13;25(17):F21-7. doi: 10.1097/QAD.0b013e32834bac44. AIDS. 2011. PMID: 21857492
BACKGROUND: Recent data indicate that seroprevalence of sexually transmitted hepatitis C virus (HCV) infection among MSM is stabilizing in Amsterdam. However, little is known about the incidence of HCV re-infection in MSM who have cleared their HCV infection. We, th …
BACKGROUND: Recent data indicate that seroprevalence of sexually transmitted hepatitis C virus (HCV) infection among MSM is stabilizi …
Risk Factors for Sexual Transmission of Hepatitis C Virus Among Human Immunodeficiency Virus-Infected Men Who Have Sex With Men: A Case-Control Study.
Vanhommerig JW, Lambers FA, Schinkel J, Geskus RB, Arends JE, van de Laar TJ, Lauw FN, Brinkman K, Gras L, Rijnders BJ, van der Meer JT, Prins M; MOSAIC (MSM Observational Study of Acute Infection With Hepatitis C) Study Group; van der Meer JT, Molenkamp R, Mutschelknauss M, Nobel HE, Reesink HW, Schinkel J, van der Valk M, van den Berk GE, Brinkman K, Kwa D, van der Meche N, Toonen A, Vos D, van Broekhuizen M, Lauw FN, Mulder JW, Arends JE, van Kessel A, de Kroon I, Boonstra A, van der Ende ME, Hullegie S, Rijnders BJ, van de Laar TJ, Gras L, Smit C, Lambers FA, Prins M, Vanhommerig JW, van der Veldt W. Vanhommerig JW, et al. Open Forum Infect Dis. 2015 Aug 6;2(3):ofv115. doi: 10.1093/ofid/ofv115. eCollection 2015 Sep. Open Forum Infect Dis. 2015. PMID: 26634219 Free PMC article.
Methods. From 2009 onwards, HIV-infected MSM with acute HCV infection and controls (HIV-monoinfected MSM) were prospectively included in the MOSAIC (MSM Observational Study of Acute Infection with hepatitis C) study at 5 large HIV outpatient clinics in …
Methods. From 2009 onwards, HIV-infected MSM with acute HCV infection and controls (HIV-monoinfected MSM) were prospectively i …
Bile-salt stimulated lipase polymorphisms do not associate with HCV susceptibility.
Steba GS, Koekkoek SM, Prins M, Brinkman K, Kwa D, van der Meer JTM, van der Valk M, Molenkamp R, Pollakis G, Schinkel J, Paxton WA; MOSAIC (MSM observational Study of Acute infection with Hepatitis C) study group. Steba GS, et al. Virus Res. 2019 Dec;274:197715. doi: 10.1016/j.virusres.2019.197715. Epub 2019 Oct 14. Virus Res. 2019. PMID: 31622635
DNA was isolated from the HIV-1 infected MSM cohort (MOSAIC) composed of HCV multiple exposed uninfected (MEU) (N = 30) and multiple exposed HCV infected (MEI) (N = 32) individuals and from the Amsterdam cohort studies (ACS) intravenous drug using (IDU) cohort (22 M …
DNA was isolated from the HIV-1 infected MSM cohort (MOSAIC) composed of HCV multiple exposed uninfected (MEU) (N = 30) and mu …
SNP rs688 within the low-density lipoprotein receptor (LDL-R) gene associates with HCV susceptibility.
Steba GS, Koekkoek SM, Tanck MWT, Vanhommerig JW, van der Meer JTM, Kwa D, Brinkman K, Prins M, Berkhout B, Pollakis G, Molenkamp R, Schinkel J, Paxton WA; MOSAIC (MSM observational Study of Acute infection with Hepatitis C) Study Group and the ACS (Amsterdam Cohort Studies). Steba GS, et al. Liver Int. 2019 Mar;39(3):463-469. doi: 10.1111/liv.13978. Epub 2018 Oct 17. Liver Int. 2019. PMID: 30260075 Free PMC article.
METHODS: Multiple exposed infected and MEU from two observational cohorts were selected. From the MSM study of acute infection with HCV (MOSAIC), HIV-1 infected MEU cases (n = 30) and HIV-1 infected MEI controls (n = 32) were selected based on reported high-risk beh …
METHODS: Multiple exposed infected and MEU from two observational cohorts were selected. From the MSM study of acute infection with H …