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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1837 1
1962 1
1963 1
1965 1
1966 1
1968 1
1969 2
1972 2
1973 1
1974 1
1975 1
1978 1
1980 1
1981 2
1984 2
1986 2
1989 2
1990 3
1991 4
1992 3
1993 4
1995 6
1997 5
1998 5
1999 6
2000 10
2001 13
2002 19
2003 13
2004 15
2005 13
2006 9
2007 8
2008 12
2009 5
2010 14
2011 19
2012 17
2013 19
2014 17
2015 22
2016 20
2017 15
2018 23
2019 20
2020 30
2021 37
2022 14
2023 23
2024 17
2025 1

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446 results

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Page 1
Notch signalling drives synovial fibroblast identity and arthritis pathology.
Wei K, Korsunsky I, Marshall JL, Gao A, Watts GFM, Major T, Croft AP, Watts J, Blazar PE, Lange JK, Thornhill TS, Filer A, Raza K, Donlin LT; Accelerating Medicines Partnership Rheumatoid Arthritis & Systemic Lupus Erythematosus (AMP RA/SLE) Consortium; Siebel CW, Buckley CD, Raychaudhuri S, Brenner MB. Wei K, et al. Among authors: major t. Nature. 2020 Jun;582(7811):259-264. doi: 10.1038/s41586-020-2222-z. Epub 2020 Apr 22. Nature. 2020. PMID: 32499639 Free PMC article.
Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases.
Korsunsky I, Wei K, Pohin M, Kim EY, Barone F, Major T, Taylor E, Ravindran R, Kemble S, Watts GFM, Jonsson AH, Jeong Y, Athar H, Windell D, Kang JB, Friedrich M, Turner J, Nayar S, Fisher BA, Raza K, Marshall JL, Croft AP, Tamura T, Sholl LM, Vivero M, Rosas IO, Bowman SJ, Coles M, Frei AP, Lassen K, Filer A, Powrie F, Buckley CD, Brenner MB, Raychaudhuri S. Korsunsky I, et al. Among authors: major t. Med. 2022 Jul 8;3(7):481-518.e14. doi: 10.1016/j.medj.2022.05.002. Epub 2022 May 31. Med. 2022. PMID: 35649411 Free PMC article.
An update on the genetics of hyperuricaemia and gout.
Major TJ, Dalbeth N, Stahl EA, Merriman TR. Major TJ, et al. Nat Rev Rheumatol. 2018 Jun;14(6):341-353. doi: 10.1038/s41584-018-0004-x. Nat Rev Rheumatol. 2018. PMID: 29740155 Review.
The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts.
Friščić J, Böttcher M, Reinwald C, Bruns H, Wirth B, Popp SJ, Walker KI, Ackermann JA, Chen X, Turner J, Zhu H, Seyler L, Euler M, Kirchner P, Krüger R, Ekici AB, Major T, Aust O, Weidner D, Fischer A, Andes FT, Stanojevic Z, Trajkovic V, Herrmann M, Korb-Pap A, Wank I, Hess A, Winter J, Wixler V, Distler J, Steiner G, Kiener HP, Frey B, Kling L, Raza K, Frey S, Kleyer A, Bäuerle T, Hughes TR, Grüneboom A, Steffen U, Krönke G, Croft AP, Filer A, Köhl J, Klein K, Buckley CD, Schett G, Mougiakakos D, Hoffmann MH. Friščić J, et al. Among authors: major t. Immunity. 2021 May 11;54(5):1002-1021.e10. doi: 10.1016/j.immuni.2021.03.003. Epub 2021 Mar 23. Immunity. 2021. PMID: 33761330 Free article.
A genome-wide association analysis reveals new pathogenic pathways in gout.
Major TJ, Takei R, Matsuo H, Leask MP, Sumpter NA, Topless RK, Shirai Y, Wang W, Cadzow MJ, Phipps-Green AJ, Li Z, Ji A, Merriman ME, Morice E, Kelley EE, Wei WH, McCormick SPA, Bixley MJ, Reynolds RJ, Saag KG, Fadason T, Golovina E, O'Sullivan JM, Stamp LK, Dalbeth N, Abhishek A, Doherty M, Roddy E, Jacobsson LTH, Kapetanovic MC, Melander O, Andrés M, Pérez-Ruiz F, Torres RJ, Radstake T, Jansen TL, Janssen M, Joosten LAB, Liu R, Gaal OI, Crişan TO, Rednic S, Kurreeman F, Huizinga TWJ, Toes R, Lioté F, Richette P, Bardin T, Ea HK, Pascart T, McCarthy GM, Helbert L, Stibůrková B, Tausche AK, Uhlig T, Vitart V, Boutin TS, Hayward C, Riches PL, Ralston SH, Campbell A, MacDonald TM; FAST Study Group; Nakayama A, Takada T, Nakatochi M, Shimizu S, Kawamura Y, Toyoda Y, Nakaoka H, Yamamoto K, Matsuo K, Shinomiya N, Ichida K; Japan Gout Genomics Consortium; Lee C; Asia Pacific Gout Consortium; Bradbury LA, Brown MA, Robinson PC, Buchanan RRC, Hill CL, Lester S, Smith MD, Rischmueller M, Choi HK, Stahl EA, Miner JN, Solomon DH, Cui J, Giacomini KM, Brackman DJ, Jorgenson EM; GlobalGout Genetics Consortium; Liu H, Susztak K; 23andMe Research Team; Shringarpure S, So A, Okada Y, Li C,… See abstract for full author list ➔ Major TJ, et al. Nat Genet. 2024 Nov;56(11):2392-2406. doi: 10.1038/s41588-024-01921-5. Epub 2024 Oct 15. Nat Genet. 2024. PMID: 39406924
Tissue-resident, extravascular Ly6c- monocytes are critical for inflammation in the synovium.
Montgomery AB, Chen SY, Wang Y, Gadhvi G, Mayr MG, Cuda CM, Dominguez S, Moradeke Makinde HK, Gurra MG, Misharin AV, Mandelin AM, Ruderman EM, Thakrar A, Brar S, Carns M, Aren K, Akbarpour M, Filer A, Nayar S, Teososio A, Major T, Bharat A, Budinger GRS, Winter DR, Perlman H. Montgomery AB, et al. Among authors: major t. Cell Rep. 2023 May 30;42(5):112513. doi: 10.1016/j.celrep.2023.112513. Epub 2023 May 18. Cell Rep. 2023. PMID: 37204925 Free PMC article.
Inflammation causes remodeling of mitochondrial cytochrome c oxidase mediated by the bifunctional gene C15orf48.
Clayton SA, Daley KK, MacDonald L, Fernandez-Vizarra E, Bottegoni G, O'Neil JD, Major T, Griffin D, Zhuang Q, Adewoye AB, Woolcock K, Jones SW, Goodyear C, Elmesmari A, Filer A, Tennant DA, Alivernini S, Buckley CD, Pitceathly RDS, Kurowska-Stolarska M, Clark AR. Clayton SA, et al. Among authors: major t. Sci Adv. 2021 Dec 10;7(50):eabl5182. doi: 10.1126/sciadv.abl5182. Epub 2021 Dec 8. Sci Adv. 2021. PMID: 34878835 Free PMC article.
Deconstructing compassionate conservation.
Hayward MW, Callen A, Allen BL, Ballard G, Broekhuis F, Bugir C, Clarke RH, Clulow J, Clulow S, Daltry JC, Davies-Mostert HT, Fleming PJS, Griffin AS, Howell LG, Kerley GIH, Klop-Toker K, Legge S, Major T, Meyer N, Montgomery RA, Moseby K, Parker DM, Périquet S, Read J, Scanlon RJ, Seeto R, Shuttleworth C, Somers MJ, Tamessar CT, Tuft K, Upton R, Valenzuela-Molina M, Wayne A, Witt RR, Wüster W. Hayward MW, et al. Among authors: major t. Conserv Biol. 2019 Aug;33(4):760-768. doi: 10.1111/cobi.13366. Conserv Biol. 2019. PMID: 31206825
[Radiotherapy and radio-chemotherapy of cervical cancer].
Polgár C, Major T, Varga S. Polgár C, et al. Among authors: major t. Magy Onkol. 2022 Dec 31;66(4):307-314. Epub 2022 Dec 6. Magy Onkol. 2022. PMID: 36602251 Free article. Review. Hungarian.
446 results