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Page 1
Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis: The BLING III Randomized Clinical Trial.
Dulhunty JM, Brett SJ, De Waele JJ, Rajbhandari D, Billot L, Cotta MO, Davis JS, Finfer S, Hammond NE, Knowles S, Liu X, McGuinness S, Mysore J, Paterson DL, Peake S, Rhodes A, Roberts JA, Roger C, Shirwadkar C, Starr T, Taylor C, Myburgh JA, Lipman J; BLING III Study Investigators. Dulhunty JM, et al. JAMA. 2024 Aug 27;332(8):629-637. doi: 10.1001/jama.2024.9779. JAMA. 2024. PMID: 38864155 Free PMC article. Clinical Trial.
Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest.
Dankiewicz J, Cronberg T, Lilja G, Jakobsen JC, Levin H, Ullén S, Rylander C, Wise MP, Oddo M, Cariou A, Bělohlávek J, Hovdenes J, Saxena M, Kirkegaard H, Young PJ, Pelosi P, Storm C, Taccone FS, Joannidis M, Callaway C, Eastwood GM, Morgan MPG, Nordberg P, Erlinge D, Nichol AD, Chew MS, Hollenberg J, Thomas M, Bewley J, Sweet K, Grejs AM, Christensen S, Haenggi M, Levis A, Lundin A, Düring J, Schmidbauer S, Keeble TR, Karamasis GV, Schrag C, Faessler E, Smid O, Otáhal M, Maggiorini M, Wendel Garcia PD, Jaubert P, Cole JM, Solar M, Borgquist O, Leithner C, Abed-Maillard S, Navarra L, Annborn M, Undén J, Brunetti I, Awad A, McGuigan P, Bjørkholt Olsen R, Cassina T, Vignon P, Langeland H, Lange T, Friberg H, Nielsen N; TTM2 Trial Investigators. Dankiewicz J, et al. N Engl J Med. 2021 Jun 17;384(24):2283-2294. doi: 10.1056/NEJMoa2100591. N Engl J Med. 2021. PMID: 34133859 Free article. Clinical Trial.
Mild Hypercapnia or Normocapnia after Out-of-Hospital Cardiac Arrest.
Eastwood G, Nichol AD, Hodgson C, Parke RL, McGuinness S, Nielsen N, Bernard S, Skrifvars MB, Stub D, Taccone FS, Archer J, Kutsogiannis D, Dankiewicz J, Lilja G, Cronberg T, Kirkegaard H, Capellier G, Landoni G, Horn J, Olasveengen T, Arabi Y, Chia YW, Markota A, Hænggi M, Wise MP, Grejs AM, Christensen S, Munk-Andersen H, Granfeldt A, Andersen GØ, Qvigstad E, Flaa A, Thomas M, Sweet K, Bewley J, Bäcklund M, Tiainen M, Iten M, Levis A, Peck L, Walsham J, Deane A, Ghosh A, Annoni F, Chen Y, Knight D, Lesona E, Tlayjeh H, Svenšek F, McGuigan PJ, Cole J, Pogson D, Hilty MP, Düring JP, Bailey MJ, Paul E, Ady B, Ainscough K, Hunt A, Monahan S, Trapani T, Fahey C, Bellomo R; TAME Study Investigators. Eastwood G, et al. N Engl J Med. 2023 Jul 6;389(1):45-57. doi: 10.1056/NEJMoa2214552. Epub 2023 Jun 15. N Engl J Med. 2023. PMID: 37318140 Clinical Trial.
The predictive value of highly malignant EEG patterns after cardiac arrest: evaluation of the ERC-ESICM recommendations.
Turella S, Dankiewicz J, Friberg H, Jakobsen JC, Leithner C, Levin H, Lilja G, Moseby-Knappe M, Nielsen N, Rossetti AO, Sandroni C, Zubler F, Cronberg T, Westhall E; TTM2-trial investigators. Turella S, et al. Intensive Care Med. 2024 Jan;50(1):90-102. doi: 10.1007/s00134-023-07280-9. Epub 2024 Jan 3. Intensive Care Med. 2024. PMID: 38172300 Free PMC article.
Protocolized reduction of non-resuscitation fluids versus usual care in septic shock patients (REDUSE): a randomized multicentre feasibility trial.
Lindén A, Spångfors M, Olsen MH, Fisher J, Lilja G, Sjövall F, Jungner M, Lengquist M, Kander T, Samuelsson L, Johansson J, Palmnäs E, Undén J, Oras J, Cronhjort M, Chew M, Linder A, Lipcsey M, Nielsen N, Jakobsen JC, Bentzer P; REDUSE Trial Group. Lindén A, et al. Crit Care. 2024 May 17;28(1):166. doi: 10.1186/s13054-024-04952-w. Crit Care. 2024. PMID: 38760833 Free PMC article. Clinical Trial.
Oxygen targets and 6-month outcome after out of hospital cardiac arrest: a pre-planned sub-analysis of the targeted hypothermia versus targeted normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial.
Robba C, Badenes R, Battaglini D, Ball L, Sanfilippo F, Brunetti I, Jakobsen JC, Lilja G, Friberg H, Wendel-Garcia PD, Young PJ, Eastwood G, Chew MS, Unden J, Thomas M, Joannidis M, Nichol A, Lundin A, Hollenberg J, Hammond N, Saxena M, Martin A, Solar M, Taccone FS, Dankiewicz J, Nielsen N, Grejs AM, Ebner F, Pelosi P; TTM2 Trial collaborators. Robba C, et al. Crit Care. 2022 Oct 21;26(1):323. doi: 10.1186/s13054-022-04186-8. Crit Care. 2022. PMID: 36271410 Free PMC article. Clinical Trial.
Intensive care unit burden is associated with increased mortality in critically ill COVID-19 patients.
Didriksson I, Leffler M, Spångfors M, Lindberg S, Reepalu A, Nilsson A, Cronqvist J, Andertun S, Nelderup M, Jungner M, Johnsson P, Lilja G, Frigyesi A, Friberg H. Didriksson I, et al. Among authors: nelderup m. Acta Anaesthesiol Scand. 2023 Mar;67(3):329-338. doi: 10.1111/aas.14184. Epub 2022 Dec 28. Acta Anaesthesiol Scand. 2023. PMID: 36537243 Free PMC article.
Prolonged Fatigue and Mental Health Challenges in Critical COVID-19 Survivors.
Hultgren M, Didriksson I, Håkansson A, Andertun S, Frigyesi A, Mellerstedt E, Nelderup M, Nilsson AC, Reepalu A, Spångfors M, Friberg H, Lilja G. Hultgren M, et al. Among authors: nelderup m. J Intensive Care Med. 2024 Dec;39(12):1238-1249. doi: 10.1177/08850666241255328. Epub 2024 Jul 23. J Intensive Care Med. 2024. PMID: 39042144 Free PMC article.
Ventilatory settings in the initial 72 h and their association with outcome in out-of-hospital cardiac arrest patients: a preplanned secondary analysis of the targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest (TTM2) trial.
Robba C, Badenes R, Battaglini D, Ball L, Brunetti I, Jakobsen JC, Lilja G, Friberg H, Wendel-Garcia PD, Young PJ, Eastwood G, Chew MS, Unden J, Thomas M, Joannidis M, Nichol A, Lundin A, Hollenberg J, Hammond N, Saxena M, Annborn M, Solar M, Taccone FS, Dankiewicz J, Nielsen N, Pelosi P; TTM2 Trial Collaborators. Robba C, et al. Intensive Care Med. 2022 Aug;48(8):1024-1038. doi: 10.1007/s00134-022-06756-4. Epub 2022 Jul 2. Intensive Care Med. 2022. PMID: 35780195 Free PMC article.