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Challenges with advanced therapy medicinal products and how to meet them.
Committee for Advanced Therapies (CAT); CAT Scientific Secretariat; Schneider CK, Salmikangas P, Jilma B, Flamion B, Todorova LR, Paphitou A, Haunerova I, Maimets T, Trouvin JH, Flory E, Tsiftsoglou A, Sarkadi B, Gudmundsson K, O'Donovan M, Migliaccio G, Ancāns J, Maciulaitis R, Robert JL, Samuel A, Ovelgönne JH, Hystad M, Fal AM, Lima BS, Moraru AS, Turcáni P, Zorec R, Ruiz S, Akerblom L, Narayanan G, Kent A, Bignami F, Dickson JG, Niederwieser D, Figuerola-Santos MA, Reischl IG, Beuneu C, Georgiev R, Vassiliou M, Pychova A, Clausen M, Methuen T, Lucas S, Schüssler-Lenz M, Kokkas V, Buzás Z, MacAleenan N, Galli MC, Linē A, Gulbinovic J, Berchem G, Fraczek M, Menezes-Ferreira M, Vilceanu N, Hrubisko M, Marinko P, Timón M, Cheng W, Crosbie GA, Meade N, di Paola ML, VandenDriessche T, Ljungman P, D'Apote L, Oliver-Diaz O, Büttel I, Celis P. Committee for Advanced Therapies (CAT), et al. Nat Rev Drug Discov. 2010 Mar;9(3):195-201. doi: 10.1038/nrd3052. Nat Rev Drug Discov. 2010. PMID: 20190786 Review.
Ultra-processed food consumption is associated with the acceleration of biological aging in the Moli-sani Study.
Esposito S, Gialluisi A, Di Castelnuovo A, Costanzo S, Pepe A, Ruggiero E, De Curtis A, Persichillo M, Cerletti C, Donati MB, de Gaetano G, Iacoviello L, Bonaccio M; Moli-sani Study Investigators; Steering Committee; Scientific Secretariat; Safety and Ethical Committee; External Event Adjudicating Committee; Baseline and Follow-up Data Management; Data Analysis; Biobank, Molecular and Genetic Laboratory; Recruitment Staff; Communication and Press Office. Esposito S, et al. Am J Clin Nutr. 2024 Dec;120(6):1432-1440. doi: 10.1016/j.ajcnut.2024.10.006. Epub 2024 Nov 4. Am J Clin Nutr. 2024. PMID: 39500680
The sensitivity of review results to methods used to appraise and incorporate trial quality into data synthesis.
van der Velde G, van Tulder M, Côté P, Hogg-Johnson S, Aker P, Cassidy JD; Scientific Secretariat of The Bone and Joint Decade 2000-2010 Task Force on Neck Pain and Its Associated Disorders; Carragee E, Carroll L, Guzman J, Haldeman S, Holm L, Hurwitz E, Nordin M, Peloso P. van der Velde G, et al. Spine (Phila Pa 1976). 2007 Apr 1;32(7):796-806. doi: 10.1097/01.brs.0000258903.67718.d5. Spine (Phila Pa 1976). 2007. PMID: 17414916 Review.
Use of unregulated stem-cell based medicinal products.
Committee for Advanced Therapies and CAT Scientific Secretariat. Committee for Advanced Therapies and CAT Scientific Secretariat. Lancet. 2010 Aug 14;376(9740):514. doi: 10.1016/S0140-6736(10)61249-4. Lancet. 2010. PMID: 20709228 No abstract available.