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16 results

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Lipoprotein-associated phospholipase A2, homocysteine, and Alzheimer's disease.
Doody RS, Demirovic J, Ballantyne CM, Chan W, Barber R, Powell S, Pavlik V; Texas Alzheimer's Disease Research and Care Consortium. Doody RS, et al. Alzheimers Dement (Amst). 2015 Sep 21;1(4):464-71. doi: 10.1016/j.dadm.2015.08.001. eCollection 2015 Dec. Alzheimers Dement (Amst). 2015. PMID: 27239525 Free PMC article.
INTRODUCTION: Lipoprotein-associated phospholipase A2 (Lp-PLA2) and homocysteine (Hcy) have been linked to inflammation and Alzheimer's disease (AD). Using a case-control design, we examined their independent effects and interactions with cardiovascular di …
INTRODUCTION: Lipoprotein-associated phospholipase A2 (Lp-PLA2) and homocysteine (Hcy) have been linked to inflammation and Alzheimer …
Biomarkers of Alzheimer's disease among Mexican Americans.
O'Bryant SE, Xiao G, Edwards M, Devous M, Gupta VB, Martins R, Zhang F, Barber R; Texas Alzheimer's Research and Care Consortium (TARCC). O'Bryant SE, et al. J Alzheimers Dis. 2013;34(4):841-9. doi: 10.3233/JAD-122074. J Alzheimers Dis. 2013. PMID: 23313927 Free PMC article.
BACKGROUND: Mexican Americans are the fastest aging segment of the U.S. population, yet little scientific literature exists regarding the Alzheimer's disease (AD) among this segment of the population. The extant literature suggests that biomarkers of AD will …
BACKGROUND: Mexican Americans are the fastest aging segment of the U.S. population, yet little scientific literature exists regarding the …
An 11-Fold Higher Risk of Incident Mild Cognitive Impairment With Hispanic Ethnicity and Baseline Neuropsychiatric Symptoms.
Salazar R, Dwivedi AK, Alvarado LA, Escamilla M; Texas Alzheimer’s Research and Care Consortium. Salazar R, et al. J Neuropsychiatry Clin Neurosci. 2024 Aug 22:appineuropsych20230180. doi: 10.1176/appi.neuropsych.20230180. Online ahead of print. J Neuropsychiatry Clin Neurosci. 2024. PMID: 39169739
This study explored ethnic differences and the effects of baseline NPSs on incident mild cognitive impairment (MCI) among 386 Hispanic and non-Hispanic participants from the Texas Harris Alzheimer's Research Study. METHODS: Data on NPSs from the Neurop …
This study explored ethnic differences and the effects of baseline NPSs on incident mild cognitive impairment (MCI) among 386 Hispanic and n …
Does ethnicity moderate dementia's biomarkers?
Royall DR, Palmer RF; Texas Alzheimer's Research and Care Consortium. Royall DR, et al. Neurobiol Aging. 2014 Feb;35(2):336-44. doi: 10.1016/j.neurobiolaging.2013.08.006. Epub 2013 Sep 18. Neurobiol Aging. 2014. PMID: 24054829
In this study, we associate delta with cytokines and other serum biomarkers in a well characterized Alzheimer's disease cohort, the Texas Alzheimer's Research and Care Consortium. Independent of covariates, delta is associated sign …
In this study, we associate delta with cytokines and other serum biomarkers in a well characterized Alzheimer's disease …
Molecular neuropsychology: creation of test-specific blood biomarker algorithms.
O'Bryant SE, Xiao G, Barber R, Cullum CM, Weiner M, Hall J, Edwards M, Grammas P, Wilhelmsen K, Doody R, Diaz-Arrastia R; Texas Alzheimer’s Research and Care Consortium. O'Bryant SE, et al. Dement Geriatr Cogn Disord. 2014;37(1-2):45-57. doi: 10.1159/000345605. Epub 2013 Jan 3. Dement Geriatr Cogn Disord. 2014. PMID: 24107792 Free PMC article.
Serum multiplex biomarker data were analyzed on 108 proteins from 395 participants (197 Alzheimer patients and 198 controls) from the Texas Alzheimer's Research and Care Consortium. ...
Serum multiplex biomarker data were analyzed on 108 proteins from 395 participants (197 Alzheimer patients and 198 controls) from the …
Total testosterone and neuropsychiatric symptoms in elderly men with Alzheimer's disease.
Hall JR, Wiechmann AR, Cunningham RL, Johnson LA, Edwards M, Barber RC, Singh M, Winter S, O'Bryant SE; Texas Alzheimer’s Research and Care Consortium. Hall JR, et al. Alzheimers Res Ther. 2015 May 1;7(1):24. doi: 10.1186/s13195-015-0107-4. eCollection 2015. Alzheimers Res Ther. 2015. PMID: 25937840 Free PMC article.
INTRODUCTION: There has been a significant increase in the use of testosterone in aging men, but little investigation into its impact on men with Alzheimer's disease (AD). The findings of the few studies that have been done are inconsistent. ...METHODS: The s …
INTRODUCTION: There has been a significant increase in the use of testosterone in aging men, but little investigation into its impact on men …
The link between C-reactive protein and Alzheimer's disease among Mexican Americans.
O'Bryant SE, Johnson L, Edwards M, Soares H, Devous MD, Ross S, Rohlfing G, Hall J; Texas Alzheimer’s Research & Care Consortium. O'Bryant SE, et al. J Alzheimers Dis. 2013;34(3):701-6. doi: 10.3233/JAD-122071. J Alzheimers Dis. 2013. PMID: 23254637 Free PMC article.
BACKGROUND: The aim of this study is to evaluate the link between C-reactive protein (CRP) and Alzheimer's disease (AD) and mild cognitive impairment (MCI) among Mexican Americans. METHODS: Non-fasting serum CRP levels, Mini-Mental State Examination scores, a …
BACKGROUND: The aim of this study is to evaluate the link between C-reactive protein (CRP) and Alzheimer's disease (AD) …
A blood-based screening tool for Alzheimer's disease that spans serum and plasma: findings from TARC and ADNI.
O'Bryant SE, Xiao G, Barber R, Huebinger R, Wilhelmsen K, Edwards M, Graff-Radford N, Doody R, Diaz-Arrastia R; Texas Alzheimer's Research & Care Consortium; Alzheimer's Disease Neuroimaging Initiative. O'Bryant SE, et al. PLoS One. 2011;6(12):e28092. doi: 10.1371/journal.pone.0028092. Epub 2011 Dec 7. PLoS One. 2011. PMID: 22163278 Free PMC article.
CONTEXT: There is no rapid and cost effective tool that can be implemented as a front-line screening tool for Alzheimer's disease (AD) at the population level. OBJECTIVE: To generate and cross-validate a blood-based screener for AD that yields acceptable accu …
CONTEXT: There is no rapid and cost effective tool that can be implemented as a front-line screening tool for Alzheimer's d …
A blood-based algorithm for the detection of Alzheimer's disease.
O'Bryant SE, Xiao G, Barber R, Reisch J, Hall J, Cullum CM, Doody R, Fairchild T, Adams P, Wilhelmsen K, Diaz-Arrastia R; Texas Alzheimer’s Research and Care Consortium. O'Bryant SE, et al. Dement Geriatr Cogn Disord. 2011;32(1):55-62. doi: 10.1159/000330750. Epub 2011 Aug 24. Dement Geriatr Cogn Disord. 2011. PMID: 21865746 Free PMC article.
BACKGROUND: We previously created a serum-based algorithm that yielded excellent diagnostic accuracy in Alzheimer's disease. The current project was designed to refine that algorithm by reducing the number of serum proteins and by including clinical labs. ... …
BACKGROUND: We previously created a serum-based algorithm that yielded excellent diagnostic accuracy in Alzheimer's disease …
Selection for depression-specific dementia cases with replication in two cohorts.
Royall DR, Palmer RF; Alzheimer’s Disease Neuroimaging Initiative (ADNI) and the Texas Alzheimer’s Research and Care Consortium (TARCC). Royall DR, et al. PLoS One. 2019 May 31;14(5):e0216413. doi: 10.1371/journal.pone.0216413. eCollection 2019. PLoS One. 2019. PMID: 31150419 Free PMC article.
We use a novel "off-diagonal" CHI SQ algorithm to demonstrate our ability to select individuals demented solely by depression's effect in both the Texas Alzheimer's Research and Care Consortium (TARCC) (N 3,500), and the Alzheimer's Di …
We use a novel "off-diagonal" CHI SQ algorithm to demonstrate our ability to select individuals demented solely by depression's effect in bo …
16 results