@article{wellstead_feedback_2006,
  abstract = {In its broadest definition, systems biology is the application of a `systems' way of thinking about and doing cell biology. By implication, this also invites us to consider a systems approach in the context of medicine and the treatment of disease. In particular, the idea that systems biology can form the basis of a personalised, predictive medicine will require that much closer attention is paid to the analytic properties of the feedback loops which will be set up by a personalised approach to healthcare. To emphasize the role that feedback theory will play in understanding personalised medicine, we use the term feedback medicine to describe the issues {outlined.In} these notes we consider feedback and control systems concepts applied to two important themes in medical systems biology - personalised medicine and combinatorial intervention. In particular, we formulate a feedback control interpretation for the administration of medicine, and relate them to various forms of medical treatment.},
  added-at = {2010-09-17T16:55:15.000+0200},
  author = {Wellstead, Peter and Middleton, Rick and Wolkenhauer, Olaf},
  biburl = {https://www.bibsonomy.org/bibtex/2403355034cdb949c45ad765d5c160527/ra1602},
  interhash = {a8ee72dadcb7b50001a9dc7c83b37ffa},
  intrahash = {403355034cdb949c45ad765d5c160527},
  journal = {q-bio/0603032},
  keywords = {- Biology Methods, Organs Quantitative Rostock SBI Tissues and},
  month = mar,
  shorttitle = {Feedback Medicine},
  timestamp = {2010-09-17T16:55:28.000+0200},
  title = {Feedback Medicine: Control Systems Concepts in Personalised, Predictive Medicine and Combinatorial Intervention},
  url = {http://arxiv.org/abs/q-bio/0603032},
  year = 2006
}