Synthesis and Characterization of New 2-Thiophen 3'4-Dimethylbenzaldehyde as 3,4-Dihydropyrimidinone Derivatives
L. Naser. CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCE, 4 (5):
33-37(September 2023)
Abstract
Background: This study it has been successfully synthesized and characterized in the form of 3,4-dihydropyrimidin-2-(1H) ones (1-3) a derivative. This compound were synthesized by reaction of 1,3-cyclohexane dione in the presence of ethanol, urea, and aromatic aldehyde(t-BuOK).It has been characterized spectroscopically (For example, 13C-NMR, 1H-NMR, and FT-IR) For the purpose of showing the chemical composition and the final result of the industrial compound.
Methods: The design of this research was cross-sectional. descriptive investigation,which included the preparation of a group of polypyrimidine derivatives.
Results: In the current work, 1,3-cyclohexandione, aromatic aldehydes, and urea are combined with ethanol to create 3,4-Dihydropyrimidine. The chemical composition of molecules was determined via spectral analysis (1-2)a.
Conclusion: When t-BuOK was used as a catalyst in this work to create three DHMP compounds, it produced outstanding results with a high yield and a quicker reaction time than the assistant factor.
%0 Journal Article
%1 noauthororeditor
%A Naser, Lina Abdullah
%D 2023
%J CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCE
%K , 3 4-dihydropyrimidine-2-(1H)-ones Biginilli reaction with
%N 5
%P 33-37
%T Synthesis and Characterization of New 2-Thiophen 3'4-Dimethylbenzaldehyde as 3,4-Dihydropyrimidinone Derivatives
%U https://cajmns.centralasianstudies.org/index.php/CAJMNS/article/view/1778/1871
%V 4
%X Background: This study it has been successfully synthesized and characterized in the form of 3,4-dihydropyrimidin-2-(1H) ones (1-3) a derivative. This compound were synthesized by reaction of 1,3-cyclohexane dione in the presence of ethanol, urea, and aromatic aldehyde(t-BuOK).It has been characterized spectroscopically (For example, 13C-NMR, 1H-NMR, and FT-IR) For the purpose of showing the chemical composition and the final result of the industrial compound.
Methods: The design of this research was cross-sectional. descriptive investigation,which included the preparation of a group of polypyrimidine derivatives.
Results: In the current work, 1,3-cyclohexandione, aromatic aldehydes, and urea are combined with ethanol to create 3,4-Dihydropyrimidine. The chemical composition of molecules was determined via spectral analysis (1-2)a.
Conclusion: When t-BuOK was used as a catalyst in this work to create three DHMP compounds, it produced outstanding results with a high yield and a quicker reaction time than the assistant factor.
@article{noauthororeditor,
abstract = {Background: This study it has been successfully synthesized and characterized in the form of [3,4-dihydropyrimidin-2-(1H) ones] (1-3) a derivative. This compound were synthesized by reaction of 1,3-cyclohexane dione in the presence of ethanol, urea, and aromatic aldehyde(t-BuOK).It has been characterized spectroscopically (For example, 13C-NMR, 1H-NMR, and FT-IR) For the purpose of showing the chemical composition and the final result of the industrial compound.
Methods: The design of this research was cross-sectional. descriptive investigation,which included the preparation of a group of polypyrimidine derivatives.
Results: In the current work, 1,3-cyclohexandione, aromatic aldehydes, and urea are combined with ethanol to create 3,4-Dihydropyrimidine. The chemical composition of molecules was determined via spectral analysis (1-2)a.
Conclusion: When t-BuOK was used as a catalyst in this work to create three DHMP compounds, it produced outstanding results with a high yield and a quicker reaction time than the assistant factor.},
added-at = {2024-01-11T08:04:14.000+0100},
author = {Naser, Lina Abdullah},
biburl = {https://www.bibsonomy.org/bibtex/207d3bc39a73fd6387f8e1843d019c1bf/centralasian_20},
interhash = {31b2e70539cf0798d98e322a9e43a4e2},
intrahash = {07d3bc39a73fd6387f8e1843d019c1bf},
issn = {2660-4159},
journal = {CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCE},
keywords = {, 3 4-dihydropyrimidine-2-(1H)-ones Biginilli reaction with},
language = {english},
month = sep,
number = 5,
pages = {33-37},
timestamp = {2024-01-11T08:04:14.000+0100},
title = {Synthesis and Characterization of New 2-Thiophen 3'4-Dimethylbenzaldehyde as 3,4-Dihydropyrimidinone Derivatives},
url = {https://cajmns.centralasianstudies.org/index.php/CAJMNS/article/view/1778/1871},
volume = 4,
year = 2023
}