%0 Journal Article
%1 Tasdemir2001
%A Tasdemir, H. A.
%A Buyukavci, M.
%A Akcay, F.
%A Polat, P.
%A Yildiran, A.
%A Karakelleoglu, C.
%D 2001
%J Pediatr Int
%K Alkaline Phosphatase; Bone Density; Diseases, Metabolic; Calcifediol; Calcium; Cerebral Palsy; Child; Child, Preschool; Female; Humans; Male; Parathyroid Hormone; Phosphates
%N 2
%P 157--160
%T Bone mineral density in children with cerebral palsy.
%V 43
%X BACKGROUND: The purpose of the present study was to evaluate the severity of and factors related to osteopenia in children with cerebral palsy (CP). METHODS: Bone mineral density (BMD), calcium (Ca), phosphate (P), alkaline phosphatase (ALP), creatinine, parathyroid hormone (PTH) and 25-hydroxy vitamin D3 (25OHD3) concentrations were determined in 24 children with CP (15 ambulant, nine non-ambulant), aged between 10 months and 12 years (mean (+/-SD) 4.1+/-2.9 years). These vaules were compared with data obtained from a control group. RESULTS: Adjusted mean BMD values were lower in the patient group than in controls (P<0.05). However, there was no difference between BMD values of ambulant and non-ambulant patients. The Ca and P levels of the patient group were significantly higher than those of controls (P<0.05). CONCLUSIONS: The present study showed that BMD was decreased in all children with CP, but to a greater extent in non-ambulant children with CP, and immobilization is the major effective factor on bone mineralization.