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m Changed the early "autonomic nervous system" link to point to that article rather than "dysautonomia", since it's reasonable to the that the reader is looking for basic definitions of terms this early in the article. If the article also needs a link to "dysatonomia", then we should introduce that term somewhere in the body. |
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'''Lewy body
[[Parkinson's disease dementia]] (PDD).<ref name=Gomperts2016>{{cite journal |vauthors=Gomperts SN |title=Lewy Body Dementias: Dementia With Lewy Bodies and Parkinson Disease Dementia |journal=Continuum (Minneap Minn) |volume=22 |issue=2 Dementia |pages=435–63 |date=April 2016 |pmid=27042903 |pmc=5390937 |doi=10.1212/CON.0000000000000309}}</ref><ref name=Pezzoli2017>{{cite journal |vauthors=Pezzoli S, Cagnin A, Bandmann O, Venneri A |title=Structural and Functional Neuroimaging of Visual Hallucinations in Lewy Body Disease: A Systematic Literature Review |journal=Brain Sci |volume=7 |issue=12 |pages= 84|date=July 2017 |pmid=28714891 |pmc=5532597 |doi=10.3390/brainsci7070084 |doi-access=free }}</ref><ref name= Galasko2017>{{cite journal |vauthors=Galasko D |title=Lewy Body Disorders |journal=Neurol Clin |volume=35 |issue=2 |pages=325–38 |date=May 2017 |pmid=28410662 |pmc=5912679 |doi=10.1016/j.ncl.2017.01.004 }}</ref><ref name=Kon2020/> Both are characterized by changes in thinking, movement, behavior, and mood.<ref name=Walker2015/> The two conditions have similar features and may have similar causes, and are believed to belong on a spectrum of '''Lewy body disease'''<ref name=Gomperts2016/> that includes [[Parkinson's disease]].<ref name=Kon2020>{{cite journal |vauthors=Kon T, Tomiyama M, Wakabayashi K |title=Neuropathology of Lewy body disease: Clinicopathological crosstalk between typical and atypical cases |journal=Neuropathology |volume=40 |issue=1 |pages=30–39 |date=February 2020 |pmid=31498507 |doi=10.1111/neup.12597|s2cid=201983865 |doi-access=free }}</ref> As of 2014, they were more often misdiagnosed than any other common dementia.<ref name=Taylor2014/>
The exact cause is unknown,<!-- NINDS20202 --> but involves widespread deposits of abnormal clumps of protein that form in [[neuron]]s of the diseased brain.<!-- Walker2015 --> Known as [[Lewy body|Lewy bodies]] (discovered in 1912 by [[Frederic Lewy]]<ref name= NINDS2020Book/>) and [[Lewy neurite]]s, these clumps affect both the [[central nervous system]] and the [[
==Classification==
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==Epidemiology==
{{further|Dementia with Lewy bodies#Epidemiology}}
Between 5% and 25% of diagnosed dementias in older adults are due to one of the Lewy body dementias.<ref name= Connors2018/>{{efn| Kosaka (2017) writes: "Dementia with Lewy bodies (DLB) is now well known to be the second most frequent dementia following Alzheimer disease (AD). Of all types of dementia, AD is known to account for about 50%, DLB about 20% and vascular dementia (VD) about 15%. Thus, AD, DLB, and VD are now considered to be the three major dementias."<ref>{{cite book|veditors= Kosaka K |editor-link= Kenji Kosaka (psychiatrist)|date=2017 |title= Dementia with Lewy bodies: clinical and biological aspects|edition= 1st |publisher= Springer: Japan |doi= 10.1007/978-4-431-55948-1 |isbn= 978-4-431-55948-1|s2cid= 45950966}}</ref><!-- Page v --> The NINDS (2020) says that Lewy body dementia "is one of the most common causes of dementia, after
LBD usually develops after the age of 50.<ref name= NINDS2020Book/> Men are more likely to be diagnosed than women.<ref name= NINDS2020Book/>
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{{Medical resources
| DiseasesDB =
| ICD11 = {{ICD11|6D82}}, {{ICD11|6D85.0}}
| ICD10 = {{ICD10|G31.8}}† {{ICD10|F02.8}}*
| ICD9 =
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