Arvid Carlsson: Difference between revisions

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{{Short description|Swedish neuroscientist (1923–2018)}}
{{Use dmy dates|date=July 2018}}
{{Infobox scientist
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Carlson collaborated with the drug company [[Astra AB]] (now [[AstraZeneca]]) during the 1970s and the 1980s.<ref name="Squire1998">{{cite book|url=https://books.google.com/books?id=KwlzEFWw2J8C&pg=PA53|title=The History of Neuroscience in Autobiography|first=Larry R. | last=Squire|date=1998|publisher=Elsevier|isbn=978-0-08-053405-3|page=53}}</ref> He and his colleagues were able to [[derivative (chemistry)|derive]] the first marketed [[selective serotonin reuptake inhibitor]] (SSRI), [[zimelidine]], from [[brompheniramine]].<ref name="Barondes" /> Zimelidine was later withdrawn from the market due to rare cases of [[Guillain–Barré syndrome]],<ref>{{Cite web|url=http://www.dr-bob.org/babble/20060604/msgs/654587.html|title=History: Discovery of the SSRIs (long) {{!}} Psycho-Babble|website=www.dr-bob.org|access-date=22 June 2016}}</ref> but Carlson's research paved the way for [[fluoxetine]] (Prozac), one of the most widely used prescription medicines in the world.<ref name=":1" />
 
Carlsson was still an active researcher and speaker when he was over 90 years old and, together with his daughter Lena, he worked<ref name=Gothenburg_uni>{{Cite web|url=http://www.gu.se/english/research/publication/?publicationId=165289|title=Publications card|date=25 November 2010|website=University of Gothenburg|access-date=22 June 2016|archive-date=8 August 2016|archive-url=https://web.archive.org/web/20160808101106/http://www.gu.se/english/research/publication/?publicationId=165289|url-status=dead}}</ref> on [[OSU-6162|OSU6162]], a dopamine stabilizer which alleviates symptoms of post-stroke fatigue.<ref>{{Cite web|url=http://www.brainmessenger.se/index_eng.htm|title=Arvid Carlsson and Lena Carlsson|website=www.BrainMessenger.se|access-date=22 June 2016}}</ref>
 
== Honours and awards ==
Carlsson's research on the brain's chemical signals and the resulting treatment for Parkinson's disease earned him the 2000 [[Nobel Prize in Physiology or Medicine]], which he shared with [[Paul Greengard]] and [[Eric R. Kandel]].<ref name=":0" /><ref name=":1" /> He won many other awards including Israel's [[Wolf Prize in Medicine]] (1979), the [[Japan Prize]] (1994),<ref name=":1" /> and Italy's [[Feltrinelli Prize]] (1999).<ref>{{Cite web|url=http://www.lincei.it/premi/assegnati_feltrinelli.php|title=Accademia Nazionale dei Lincei - Premi e borse di studio - Premi "Antonio Feltrinelli" finora conferiti|website=Accademia dei Lincei|language=it|archive-url=https://web.archive.org/web/20140728111117/http://www.lincei.it/premi/assegnati_feltrinelli.php|archive-date=28 July 2014|access-date=3 July 2018|url-status=dead}}</ref> He was elected as a member of the [[Royal Swedish Academy of Sciences]] in 1975.<ref name=":0" /> He was awarded an honorary Doctor of Science from the [[University of Southern California]] in 2007.<ref>{{Cite web |title=Past Recipients – Honorary Degrees |url=https://honorarydegrees.usc.edu/past-recipients/ |access-date=2024-05-08 |website=honorarydegrees.usc.edu}}</ref>
 
== Personal life ==
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Carlsson died on 29 June 2018, at the age of 95.<ref name=":0" /><ref name=":1">{{Cite news|url=https://www.washingtonpost.com/local/obituaries/arvid-carlsson-nobel-laureate-who-uncovered-a-treatment-for-parkinsons-dies-at-95/2018/07/02/c13d9aee-7e00-11e8-b660-4d0f9f0351f1_story.html|title=Arvid Carlsson, Nobel laureate who uncovered a treatment for Parkinson's, dies at 95|last=Smith|first=Harrison|date=2 July 2018|newspaper=Washington Post|access-date=3 July 2018}}</ref>
==Drugs==
 
#[[Preclamol]]
#[[FLA-57]]
#[[Rotigotine]]
#[[HW-165]]
#[[UH-232]]
#[[Nomelidine]]
#[[Zimelidine]]
#[[8-OH-DPAT]]
#[[7-OH-DPAT]]
#[[DS-121]]
==References==
{{Reflist}}
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[[Category:21st-century Swedish scientists]]
[[Category:Members of the National Academy of Medicine]]
[[Category:University of Gothenburg alumni]]