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=== Bone health ===
Elevated levels of homocysteine have also been linked to increased [[Fracture (bone)|fractures]] in elderly persons. Homocysteine auto-oxidizes and reacts with reactive oxygen intermediates, damaging endothelial cells and increasing the risk of [[thrombus]] formation.<ref>{{cite journal |doi=10.1056/NEJMoa032739 |pmid=15141042 |title=Homocysteine as a Predictive Factor for Hip Fracture in Older Persons |journal=New England Journal of Medicine |volume=350 |issue=20 |pages=2042–9 |year=2004 |last1=McLean |first1=Robert R. |last2=Jacques |first2=Paul F. |last3=Selhub |first3=Jacob |last4=Tucker |first4=Katherine L. |last5=Samelson |first5=Elizabeth J. |last6=Broe |first6=Kerry E. |last7=Hannan |first7=Marian T. |last8=Cupples |first8=L. Adrienne |last9=Kiel |first9=Douglas P. |s2cid=22853996
=== Ectopia lentis ===
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