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m The word 'presynaptic' makes no sense when used for the definition of an autoreceptor. Every neuron is presynaptic to some other neuron or to a target effector cell. |
Adding local short description: "Type of receptor located in the membranes of nerve cells", overriding Wikidata description "receptor located in the membranes of a presynaptic nerve cell that is only sensitive to the neurotransmitters or hormones released by the neuron on which the autoreceptor lies" |
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{{Short description|Type of receptor located in the membranes of nerve cells}}
An '''autoreceptor''' is a type of [[Receptor (biochemistry)|receptor]] located in the [[cell membrane|membrane]]s of [[neuron|nerve cells]]. It serves as part of a [[negative feedback]] loop in [[signal transduction]]. It is only sensitive to the [[neurotransmitter]]s or [[hormone]]s released by the neuron on which the autoreceptor sits. Similarly, a [[heteroreceptor]] is sensitive to neurotransmitters and hormones that are not released by the cell on which it sits. A given receptor can act as either an autoreceptor or a heteroreceptor, depending upon the type of transmitter released by the cell on which it is embedded.
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