List of proteins: Difference between revisions

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→‎Structure: for completeness, added links to metamorphic protein and Intrinsically disordered proteins with citations
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* [[Structural Classification of Proteins database]] (SCOP)<ref name="Andreeva_2014">{{cite journal | vauthors = Andreeva A, Howorth D, Chothia C, Kulesha E, Murzin AG | title = SCOP2 prototype: a new approach to protein structure mining | journal = Nucleic Acids Research | volume = 42 | issue = Database issue | pages = D310–4 | date = January 2014 | pmid = 24293656 | pmc = 3964979 | doi = 10.1093/nar/gkt1242 | url = }}</ref>
* [[CATH database]]<ref name="Sillitoe_2021">{{cite journal | vauthors = Sillitoe I, Bordin N, Dawson N, Waman VP, Ashford P, Scholes HM, Pang CS, Woodridge L, Rauer C, Sen N, Abbasian M, Le Cornu S, Lam SD, Berka K, Varekova IH, Svobodova R, Lees J, Orengo CA | display-authors = 6 | title = CATH: increased structural coverage of functional space | journal = Nucleic Acids Research | volume = 49 | issue = D1 | pages = D266-D273 | date = January 2021 | pmid = 33237325 | pmc = 7778904 | doi = 10.1093/nar/gkaa1079 }}</ref>
 
While most proteins adopt a single stable fold, a few proteins can rapidly interconvert between one or more folds. These are refered to as [[metamorphic protein]]s.<ref name="Dishman_2022">{{cite journal | vauthors = Dishman AF, Volkman BF | title = Design and discovery of metamorphic proteins | journal = Current Opinion in Structural Biology | volume = 74 | issue = | pages = 102380 | date = June 2022 | pmid = 35561475 | pmc = 9664977 | doi = 10.1016/j.sbi.2022.102380 }}</ref> Finally other proteins appear to be not adopt any stable conformation and are referred to as [[Intrinsically disordered proteins|intrinsically disordered]].<ref name="Trivedi_2022">{{cite journal | vauthors = Trivedi R, Nagarajaram HA | title = Intrinsically Disordered Proteins: An Overview | journal = International Journal of Molecular Sciences | volume = 23 | issue = 22 | pages = | date = November 2022 | pmid = 36430530 | pmc = 9693201 | doi = 10.3390/ijms232214050 | url = }}</ref>
 
== Function ==