Calcium pyrophosphate dihydrate crystal deposition disease: Difference between revisions

MeshID = D002805 |

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[[Image:Calcium pyrophosphate.png|thumb|[[Calcium pyrophosphate]]]]

'''Calcium pyrophosphate dihydrate disease''' ('''CPPD''') is a [[rheumatology|rheumatologic]] disorder with varied clinical manifestations due to precipitation of [[calcium pyrophosphate]] dihydrate crystals in the connective tissues. It is more commonly known by alternative names that specify certain clinical or radiographic findings, although neither is synonymous with CPPD. ''Pseudogout'' refers to the clinically evident acute [[synovitis]] with red, tender, and swollen joints that may resemble [[gout]]y arthritis (a similar condition with joint deposition of monosodium [[urate]] crystals). ''Chondrocalcinosis''<ref name="emedicine1">{{cite web | last = Rothschild | first = Bruce M | title = Calcium Pyrophosphate Deposition Disease (radiology) | url=http://www.emedicine.com/radio/topic125.htm | accessdate = 2008-02-18 }}</ref><ref name="emedicine2"/>, on the other hand, refers to the radiographic evidence of calcification in hyaline and/or fibrocartilage. ''Pyrophosphate arthropathy'' is a term that may refer to either of the above.<ref name="oxford">{{cite book | last = Longmore | first = Murray | coauthors = Ian Wilkinson, Tom Turmezei, Chee Kay Cheung | title = Oxford Handbook of Clinicial Medicine | publisher = Oxford | date = 2007 | isbn = 0-19-856837-1 | page = 841 }}</ref> Statistically, the [[knee|knee joint]] is the most commonly affected.<ref name="emedicine1"/>