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{{Orphan|date=February 2009}}
{{PBB|geneid=23293}}
'''Telomerase-binding protein EST1A''' is an [[enzyme]] that in humans is encoded by the ''SMG6'' [[gene]].<ref name="pmid12676087">{{cite journal | author = Reichenbach P, Hoss M, Azzalin CM, Nabholz M, Bucher P, Lingner J | title = A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed | journal = Curr Biol | volume = 13 | issue = 7 | pages = 568–74 | year = 2003 | month = Apr | pmid = 12676087 | pmc = | doi =10.1016/S0960-9822(03)00173-8 }}</ref><ref name="pmid12699629">{{cite journal | author = Snow BE, Erdmann N, Cruickshank J, Goldman H, Gill RM, Robinson MO, Harrington L | title = Functional conservation of the telomerase protein Est1p in humans | journal = Curr Biol | volume = 13 | issue = 8 | pages = 698–704 | year = 2003 | month = Apr | pmid = 12699629 | pmc = | doi =10.1016/S0960-9822(03)00210-0 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SMG6 Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23293| accessdate = }}</ref>
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*{{cite journal | author=Nagase T, Ishikawa K, Suyama M, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 5 |pages= 277–86 |year= 1999 |pmid= 9872452 |doi=10.1093/dnares/5.5.277 }}
*{{cite journal | author=Hoff C, Seranski P, Mollenhauer J, ''et al.'' |title=Physical and transcriptional mapping of the 17p13.3 region that is frequently deleted in human cancer. |journal=Genomics |volume=70 |issue= 1 |pages= 26–33 |year= 2001 |pmid= 11087658 |doi= 10.1006/geno.2000.6353 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Chiu SY, Serin G, Ohara O, Maquat LE |title=Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1. |journal=RNA |volume=9 |issue= 1 |pages= 77–87 |year= 2003 |pmid= 12554878 |doi=10.1261/rna.2137903 | pmc=1370372 }}
*{{cite journal | author=Ohnishi T, Yamashita A, Kashima I, ''et al.'' |title=Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7. |journal=Mol. Cell |volume=12 |issue= 5 |pages= 1187–200 |year= 2004 |pmid= 14636577 |doi=10.1016/S1097-2765(03)00443-X }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Fukuhara N, Ebert J, Unterholzner L, ''et al.'' |title=SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway. |journal=Mol. Cell |volume=17 |issue= 4 |pages= 537–47 |year= 2005 |pmid= 15721257 |doi= 10.1016/j.molcel.2005.01.010 }}
*{{cite journal | author=Azzalin CM, Lingner J |title=The human RNA surveillance factor UPF1 is required for S phase progression and genome stability. |journal=Curr. Biol. |volume=16 |issue= 4 |pages= 433–9 |year= 2006 |pmid= 16488880 |doi= 10.1016/j.cub.2006.01.018 }}
*{{cite journal | author=Takeshita D, Zenno S, Lee WC, ''et al.'' |title=Crystallization and preliminary X-ray analysis of the PIN domain of human EST1A. |journal=Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. |volume=62 |issue= Pt 7 |pages= 656–8 |year= 2006 |pmid= 16820686 |doi= 10.1107/S1744309106020057 | pmc=2242961 }}
*{{cite journal | author=Glavan F, Behm-Ansmant I, Izaurralde E, Conti E |title=Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex. |journal=
*{{cite journal | author=Takeshita D, Zenno S, Lee WC, ''et al.'' |title=Crystal structure of the PIN domain of human telomerase-associated protein EST1A. |journal=Proteins |volume=68 |issue= 4 |pages= 980–9 |year= 2007 |pmid= 17557331 |doi= 10.1002/prot.21351 }}
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