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An '''autoreceptor''' is a type of [[Receptor (biochemistry)|receptor]] located in the [[cell membrane|membrane]]s of [[presynaptic]] [[neuron|nerve cells]]. It serves as part of a [[negative feedback]] loop in [[signal transduction]]. It is only sensitive to the [[neurotransmitter]]s or [[hormone]]s released by the neuron on which the autoreceptor sits. Similarly, a [[heteroreceptor]] is sensitive to neurotransmitters and hormones that are not released by the cell on which it sits. A given receptor can act as either an autoreceptor or a heteroreceptor, depending upon the type of transmitter released by the cell on which it is embedded.
Autoreceptors may be located in any part of the cell membrane: in the [[dendrite]]s, the [[perikaryon|cell body]], the [[axon]], or the [[axon terminal]]s.<ref name=siegel>{{cite book|author=Siegel GJ, Agranoff BW, Albers RW, et al., editors.|title=Basic Neurochemistry: Molecular, Cellular and Medical Aspects. 6th edition|publisher=Lippincott-Raven|year=1999|chapter=Catecholamine Receptors|url=http://www.ncbi.nlm.nih.gov/books/NBK28032/#A880}}</ref>
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