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==Signs and symptoms==
{{refimprove
[[File:Cold symptoms cdc.jpg|left|450px|Time line for cold symptoms]]
In uncomplicated colds, cough and nasal discharge may persist for 14 days or more even after other symptoms have resolved.<ref name=CDCrhino/>
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Up to 15% of acute pharyngitis cases may be caused by bacteria, most commonly ''[[Streptococcus pyogenes]]'', a [[group A streptococcus]] in [[streptococcal pharyngitis]] ("strep throat").<ref>{{vcite journal|author=Bisno, AL|title=Acute pharyngitis|journal=N Engl J Med|year=2001|volume=344|page=205|doi=10.1056/nejm200101183440308|pmid=11172144}}</ref> Other bacterial causes are ''[[Streptococcus pneumoniae]]'', ''[[Haemophilus influenzae]]'', ''[[Corynebacterium diphtheriae]]'', ''[[Bordetella pertussis]]'', and ''[[Bacillus anthracis]]''{{citation needed|date=December 2016}}<!--The latter two also cause common cold symptoms-->.
[[Sexually transmitted infection]]s have emerged as causes of oral and pharyngeal infections.<ref name = cdcoro2016>
| url = https://www.cdc.gov/std/hpv/STDFact-HPVandOropharyngealCancer.htm | date = 2016-11-04 | accessdate = 2016-12-19 }}</ref>
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==Prevention==
There is low or very-low quality evidence that [[probiotics]] may be better than placebo in preventing acute URTIs.<ref>{{cite journal |last=Hao |first=Q |author2=Dong, BR |author3=Wu, T |title=Probiotics for preventing acute upper respiratory tract infections|journal=Cochrane database of systematic reviews (Online)|date=3 February 2015 |volume=9|pages=CD006895|pmid=25927096|doi=10.1002/14651858.CD006895.pub3|editor1-last=Dong|editor1-first=Bi Rong |issue=9}}</ref> Vaccination against [[influenza vaccines|influenza viruses]], [[adenovirus vaccine|adenoviruses]], [[measles]], [[rubella]], ''[[pneumococcal vaccine|Streptococcus pneumoniae]]'', ''[[Hib vaccine|Haemophilus influenzae]]'', [[diphtheria vaccine|diphtheria]], ''[[anthrax vaccines|Bacillus anthracis]]'', and ''[[pertussis vaccine|Bordetella pertussis]]'' may prevent them from infecting the URT or reduce the severity of the infection.{{
==Treatment==
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The Centers for Disease Control describe protocol for treating sinusitis while at the same time discouraging overuse of antibiotics:
* Target likely organisms with first-line drugs: [[Amoxicillin]], [[Amoxicillin/Clavulanate]]
*Use shortest effective course: Should see improvement in
*Consider imaging studies in recurrent or unclear cases: some sinus involvement is frequent early in the course of uncomplicated viral URI<ref name=CDCrhino/>
Treatment comprises symptomatic support usually via [[analgesics]] for headache, sore throat and muscle aches.<ref>{{cite web|title=Common Cold: Treatments and Drugs|publisher=Mayo Clinic|url=http://www.mayoclinic.com/health/common-cold/DS00056/DSECTION=treatments-and-drugs|accessdate=9 January 2010}}</ref> Moderate exercise in sedentary subjects with naturally acquired URTI probably does not alter the overall severity and duration of the illness.<ref name="pmid12893713">{{cite journal |vauthors=Weidner T, Schurr T |title=Effect of exercise on upper respiratory tract infection in sedentary subjects |journal=Br J Sports Med |volume=37 |issue=4 |pages=304–6 |date=August 2003 |pmid=12893713 |pmc=1724675 |doi= 10.1136/bjsm.37.4.304|url= }}</ref> No randomized trials have been conducted to ascertain benefits of increasing fluid intake.<ref>{{cite journal |last1=Guppy |first1=MP |last2=Mickan |first2=SM |last3=Del Mar |first3=CB |title="Drink plenty of fluids": a systematic review of evidence for this recommendation in acute respiratory infections |journal=BMJ |date=28 February 2004 |volume=328 |issue=7438 |pages=
===Antibiotics===
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{{legend|#cb0000|more than 300}}
{{refend}}]]
According to a Cochrane review, single oral dose of nasal decongestant in the common cold is modestly effective for the short term relief of congestion in adults; however, "there is insufficient data on the use of decongestants in children." Therefore, decongestants are not recommended for use in children under 12 years of age with the common cold.<ref name="spurling2013" /> Oral decongestants are also contraindicated in patients with [[hypertension]], [[coronary artery disease]], and history of bleeding [[stroke]]s.<ref>{{cite book |last=Tietze |first=KJ |chapter=Disorders related to cold and allergy |editor-last=Berardi |editor-first=Rosemary R. |title=Handbook of Nonprescription Drugs |edition=14th |location=Washington, DC |publisher=American Pharmacists Association |date=2004 |oclc=56446842 |isbn=978-1-58212-050-8 |pages=
=== Over-the-counter cough medicine ===
There is no good evidence supporting the effectiveness of over-the-counter [[Cough medicine|cough medications]] for reduce coughing in adults or children.<ref>{{Cite journal|last=Smith|first=Susan M.|last2=Schroeder|first2=Knut|last3=Fahey|first3=Tom|date=2014-11-24|title=Over-the-counter (OTC) medications for acute cough in children and adults in community settings|url=https://www.ncbi.nlm.nih.gov/pubmed/25420096|journal=The Cochrane Database of Systematic Reviews|issue=11|pages=CD001831|doi=10.1002/14651858.CD001831.pub5|issn=1469-493X|pmid=25420096}}</ref> Children under 2 years old should not be given any type of cough or cold medicine due to the potential for life threatening side effects.<ref>{{Cite web|url=http://www.fda.gov/Drugs/ResourcesForYou/SpecialFeatures/ucm263948.htm|title=Special Features - Use Caution When Giving Cough and Cold Products to Kids|last=Research|first=Center for Drug Evaluation and|website=www.fda.gov|language=en|access-date=2017-01-23}}</ref> In addition, according to the
===Alternative medicine===
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==Epidemiology==
Children have 2-9 viral respiratory illnesses per year.<ref name = CDCrhino/> In 2013 18.8 billion cases of upper respiratory infections occurred.<ref name=GBD2013/> As of 2014, upper respiratory infections caused about 3,000 deaths down from 4,000 in 1990.<ref name=Loz2012/> In the United States, URIs are the most common infectious illness in the general population. URIs are the leading reasons for people missing work and school.{{citation needed|date=December 2016}}
==See also==
* [[Lower respiratory tract infection]]
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==References==
{{reflist|2}}
==Bibliography==
*{{cite book| last=Heymann | first= David |year= 2015 | title= Control of communicable diseases manual : an official report of the American Public Health Association. |publisher= APHA Press, the American Public Health Association | isbn = 9780875530185 | ref = harv}}
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{{Inflammation}}
{{Common cold}}
[[Category:Infectious diseases]]
[[Category:Inflammations]]
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