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| genbank_id = CM000684
|caption=Human chromosome 22 pair after [[G banding|G-banding]].<br/>One is from mother, one is from father.|image2=Human_male_karyotpe_high_resolution_-_Chromosome_22.png}}
'''Chromosome 22''' is one of the 23 pairs of [[chromosome]]s in human [[cell (biology)|cells]]. Humans normally have two copies of chromosome 22 in each cell. Chromosome 22 is the second smallest human chromosome
In 1999, researchers working on the [[Human Genome Project]] announced they had determined the sequence of base pairs that make up this chromosome. Chromosome 22 was the first human chromosome to be fully sequenced.<ref>{{cite journal |last= Mayor |first= Susan |year= 1999 |title= First human chromosome is sequenced |journal= BMJ |volume= 319 |issue= 7223 |pages= 1453 |publisher= BMJ Group |pmc= 1117192 |doi=10.1136/bmj.319.7223.1453a |pmid=10582915}}</ref>
Human chromosomes are numbered by their apparent size in the [[karyotype]], with [[Chromosome 1]] being the largest and Chromosome 22 having originally been identified as the smallest. However, genome sequencing has revealed that [[Chromosome 21]] is actually smaller than Chromosome 22.
==Genes==
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