Template:PBB Growth arrest-specific 6, also known as GAS6, is a human gene coding for the Gas6 protein. It is similar to the Protein S with the same domain organization and 43% amino acid identity. It was originally found as a gene upregulated by growth arrested fibroblasts.
Interactions
GAS6 has been shown to interact with AXL receptor tyrosine kinase, MerTK and TYRO3.[1][2]
References
- ^ Mark, M R (1996). "Characterization of Gas6, a member of the superfamily of G domain-containing proteins, as a ligand for Rse and Axl". J. Biol. Chem. 271 (16). UNITED STATES: 9785–9. doi:10.1074/jbc.271.16.9785. ISSN 0021-9258. PMID 8621659.
{{cite journal}}: Cite has empty unknown parameters:|laydate=,|laysummary=, and|laysource=(help); Unknown parameter|coauthors=ignored (|author=suggested) (help); Unknown parameter|month=ignored (help)CS1 maint: unflagged free DOI (link) - ^ Nagata, K (1996). "Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases". J. Biol. Chem. 271 (47). UNITED STATES: 30022–7. doi:10.1074/jbc.271.47.30022. ISSN 0021-9258. PMID 8939948.
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Further reading
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