Telomerase-binding protein EST1A is an enzyme that in humans is encoded by the SMG6 gene.[5][6][7] The C-terminus of the EST1A protein contains a PIN domain. This structure for this domain has been determined by X-ray crystallography.[8]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000070366 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038290 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Reichenbach P, Hoss M, Azzalin CM, Nabholz M, Bucher P, Lingner J (Apr 2003). "A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed". Curr Biol. 13 (7): 568–74. doi:10.1016/S0960-9822(03)00173-8. PMID 12676087.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Snow BE, Erdmann N, Cruickshank J, Goldman H, Gill RM, Robinson MO, Harrington L (Apr 2003). "Functional conservation of the telomerase protein Est1p in humans". Curr Biol. 13 (8): 698–704. doi:10.1016/S0960-9822(03)00210-0. PMID 12699629.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ "Entrez Gene: SMG6 Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)".
- ^ Takeshita D, Zenno S, Lee WC, et al. (2006). "Crystallization and preliminary X-ray analysis of the PIN domain of human EST1A". Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62 (Pt 7): 656–8. doi:10.1107/S1744309106020057. PMC 2242961. PMID 16820686.
Further reading
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