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{{Infobox scientist
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| birth_date = {{Birth date and age|1950|9|6|df=y}}
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| birth_place = [[Amsterdam]]
| birth_place = [[Amsterdam]]
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'''Roeland "Roel" Nusse''' (born 9 September 1950, [[Amsterdam]]) is a Professor at [[Stanford University]] and an investigator at the [[Howard Hughes Medical Institute]].<ref name="HHMI Bio">{{cite web|title=Roel Nusse|url=http://www.hhmi.org/scientists/roel-nusse|publisher=HHMI|accessdate=6 September 2013}}</ref> His research was seminal in the discovery of [[Wnt signaling]], a family of pleiotropic regulators involved in development and disease.<ref>{{cite journal|last=Nusse|first=Roel|author2=Varmus, Harold |title=Three decades of Wnts: a personal perspective on how a scientific field developed|journal=The EMBO Journal|date=22 May 2012|volume=31|issue=12|pages=2670–2684|doi=10.1038/emboj.2012.146}}</ref>
'''Roeland "Roel" Nusse''' (born 9 June 1950, [[Amsterdam]]) is a professor at [[Stanford University]] and an investigator at the [[Howard Hughes Medical Institute]].<ref name="HHMI Bio">{{cite web|title=Roel Nusse|url=http://www.hhmi.org/scientists/roel-nusse|publisher=HHMI|access-date=6 September 2013}}</ref> His research was seminal in the discovery of [[Wnt signaling]], a family of pleiotropic regulators involved in development and disease.<ref>{{cite journal|last=Nusse|first=Roel|author2=Varmus, Harold |title=Three decades of Wnts: a personal perspective on how a scientific field developed|journal=The EMBO Journal|date=22 May 2012|volume=31|issue=12|pages=2670–2684|doi=10.1038/emboj.2012.146|pmid=22617420|pmc=3380217}}</ref>


==Research==
==Research==
Nusse received his BSc in biology and his [[PhD]] from the [[University of Amsterdam]]. Nusse did a postdoctoral fellowship under the guidance of [[Harold Varmus]] at the [[University of California, San Francisco]]. In 1982, Nusse and Varmus discovered the [[Wnt1]] gene.<ref>{{cite journal|last=Nusse|first=R|author2=Varmus, HE |title=Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome.|journal=Cell|date=November 1982|volume=31|issue=1|pages=99–109|pmid=6297757|doi=10.1016/0092-8674(82)90409-3}}</ref>
Nusse received his BSc in biology and his [[PhD]] from the [[University of Amsterdam]]. Nusse did a postdoctoral fellowship under the guidance of [[Harold Varmus]] at the [[University of California, San Francisco]]. In 1982, Nusse and Varmus discovered the [[Wnt1]] gene.<ref>{{cite journal|last=Nusse|first=R|author2=Varmus, HE |title=Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome.|journal=Cell|date=November 1982|volume=31|issue=1|pages=99–109|pmid=6297757|doi=10.1016/0092-8674(82)90409-3|s2cid=46024617}}</ref>


After his postdoctural fellowship, Nusse joined the Netherlands Cancer Institute expanding on the earlier work on the Wnt pathway and identifying the pathway in fruit flies. In 1990, he joined the department of [[Developmental Biology]] at [[Stanford University]]. His lab is currently focused on the role of Wnt in stem cell development and tissue repair.
After his postdoctoral fellowship, Nusse joined the Netherlands Cancer Institute expanding on the earlier work on the Wnt pathway and identifying the pathway in fruit flies. In 1990, he joined the department of [[Developmental Biology]] at [[Stanford University]]. His lab is currently focused on the role of Wnt in stem cell development and tissue repair.


==Awards==
==Awards==
Professor Nusse received the [[Peter Debye]] Prize from the [[University of Maastricht]] in 2000. He is a member of the [[U.S. National Academy of Sciences]], [[European Molecular Biology Organization]], and the [[Royal Dutch Academy of Sciences]] since 1997.<ref>{{cite web|author= |url=https://www.knaw.nl/en/members/correspondents/4605 |title=R. Nusse |publisher=Royal Netherlands Academy of Arts and Sciences |date= |accessdate=17 July 2015}}</ref> He is a fellow of the [[American Academy of Arts and Sciences]].<ref name="HHMI Bio" />
Nusse received the [[Peter Debye]] Prize from the [[University of Maastricht]] in 2000. He is a member of the [[U.S. National Academy of Sciences]], [[European Molecular Biology Organization]], and the [[Royal Netherlands Academy of Arts and Sciences]] (since 1997).<ref>{{cite web|url=https://www.knaw.nl/en/members/correspondents/4605 |archive-url=https://web.archive.org/web/20150717174850/https://www.knaw.nl/en/members/correspondents/4605 |title=Roel Nusse |publisher=Royal Netherlands Academy of Arts and Sciences |archive-date=17 July 2015}}</ref> He is a fellow of the [[American Academy of Arts and Sciences]].<ref name="HHMI Bio" /> He won a [[Breakthrough Prize in Life Sciences|Breakthrough Prize]] in 2017.<ref>{{Cite web|url=https://www.statnews.com/2016/12/04/breakthrough-prizes/|title=5 top scientists win Breakthrough Prizes in star-studded event|date=5 December 2016}}</ref> In 2020 he received the [[Canada Gairdner International Award]].<ref>{{Cite web|url=https://gairdner.org/winners/current-winners/|title=Gairdner Awards 2020 Laureates|accessdate=14 December 2021}}</ref>


==References==
==References==
{{Reflist}}
{{Reflist}}


==External links==
{{Persondata
* [http://stemcellphd.stanford.edu/faculty/roel-nusse.html Roeland Nusse Lab at Stanford University]
| NAME = Nusse, Roel

| ALTERNATIVE NAMES =
{{Breakthrough Prize laureates}}
| SHORT DESCRIPTION = Dutch biologist
{{Authority control}}
| DATE OF BIRTH = 9 September 1950

| PLACE OF BIRTH = [[Amsterdam]]
| DATE OF DEATH =
| PLACE OF DEATH =
}}
{{DEFAULTSORT:Nusse, Roel}}
{{DEFAULTSORT:Nusse, Roel}}
[[Category:1950 births]]
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[[Category:Members of the Royal Netherlands Academy of Arts and Sciences]]
[[Category:Members of the Royal Netherlands Academy of Arts and Sciences]]
[[Category:Members of the United States National Academy of Sciences]]
[[Category:Members of the United States National Academy of Sciences]]
[[Category:Molecular biologists]]
[[Category:Dutch molecular biologists]]
[[Category:People from Amsterdam]]
[[Category:Scientists from Amsterdam]]
[[Category:Stanford University School of Medicine faculty]]
[[Category:Stanford University School of Medicine faculty]]
[[Category:University of Amsterdam alumni]]
[[Category:University of Amsterdam alumni]]
[[Category:University of Amsterdam faculty]]
[[Category:Academic staff of the University of Amsterdam]]
[[Category:University of California, San Francisco alumni]]

Latest revision as of 15:33, 12 January 2023

Roeland "Roel" Nusse
Born (1950-06-09) 9 June 1950 (age 74)
Alma materUniversity of Amsterdam, University of California, San Francisco
Scientific career
InstitutionsStanford University
Academic advisorsHarold Varmus

Roeland "Roel" Nusse (born 9 June 1950, Amsterdam) is a professor at Stanford University and an investigator at the Howard Hughes Medical Institute.[1] His research was seminal in the discovery of Wnt signaling, a family of pleiotropic regulators involved in development and disease.[2]

Forschung

[edit]

Nusse received his BSc in biology and his PhD from the University of Amsterdam. Nusse did a postdoctoral fellowship under the guidance of Harold Varmus at the University of California, San Francisco. In 1982, Nusse and Varmus discovered the Wnt1 gene.[3]

After his postdoctoral fellowship, Nusse joined the Netherlands Cancer Institute expanding on the earlier work on the Wnt pathway and identifying the pathway in fruit flies. In 1990, he joined the department of Developmental Biology at Stanford University. His lab is currently focused on the role of Wnt in stem cell development and tissue repair.

Awards

[edit]

Nusse received the Peter Debye Prize from the University of Maastricht in 2000. He is a member of the U.S. National Academy of Sciences, European Molecular Biology Organization, and the Royal Netherlands Academy of Arts and Sciences (since 1997).[4] He is a fellow of the American Academy of Arts and Sciences.[1] He won a Breakthrough Prize in 2017.[5] In 2020 he received the Canada Gairdner International Award.[6]

References

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  1. ^ a b "Roel Nusse". HHMI. Retrieved 6 September 2013.
  2. ^ Nusse, Roel; Varmus, Harold (22 May 2012). "Three decades of Wnts: a personal perspective on how a scientific field developed". The EMBO Journal. 31 (12): 2670–2684. doi:10.1038/emboj.2012.146. PMC 3380217. PMID 22617420.
  3. ^ Nusse, R; Varmus, HE (November 1982). "Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome". Cell. 31 (1): 99–109. doi:10.1016/0092-8674(82)90409-3. PMID 6297757. S2CID 46024617.
  4. ^ "Roel Nusse". Royal Netherlands Academy of Arts and Sciences. Archived from the original on 17 July 2015.
  5. ^ "5 top scientists win Breakthrough Prizes in star-studded event". 5 December 2016.
  6. ^ "Gairdner Awards 2020 Laureates". Retrieved 14 December 2021.
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