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{{Infobox disease
{{Infobox medical condition (new)
| Name = Harm avoidance
| name = Harm avoidance
| DiseasesDB =
| synonyms =
| field = [[Psychiatry]]
| ICD10 = {{ICD10|F|60|6|f|60}}
| ICD9 =
| symptoms =
| complications =
| ICDO =
| OMIM =
| onset =
| MedlinePlus =
| duration =
| eMedicine_mult =
| types =
| MeshID =
| causes =
| risks =
| diagnosis =
| differential =
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}}


In [[psychology]], '''harm avoidance''' (HA) is a [[personality trait]] characterized by excessive worrying; pessimism; shyness; and being fearful, doubtful, and easily fatigued. In [[MRI]] studies HA was correlated with reduced grey matter volume in the orbito-frontal, occipital and parietal regions.<ref>Cheung G.Stability of the harm avoidance personality trait in late-life depression. Int Psychogeriatr. 2007 Aug;19(4):778-80. PMID 17726762</ref><ref>Gardini S, Cloninger CR, Venneri A. Brain Res Bull. Individual differences in personality traits reflect structural variance in specific brain regions. 2009 Jun 30;79(5):265-70. Epub 2009 Mar 28.PMID 19480986</ref>
'''Harm avoidance''' ('''HA''') is a [[personality trait]] characterized by excessive worrying; pessimism; shyness; and being fearful, doubtful, and easily fatigued. In [[MRI]] studies HA was correlated with reduced grey matter volume in the orbito-frontal, occipital and parietal regions.<ref>{{cite journal | last1 = Cheung | first1 = G | date = Aug 2007 | title = Stability of the harm avoidance personality trait in late-life depression | journal = Int Psychogeriatr | volume = 19 | issue = 4| pages = 778–80 | pmid = 17726762 | doi=10.1017/s1041610207005194| doi-access = free }}</ref><ref>{{cite journal | last1 = Gardini | first1 = S | last2 = Cloninger | first2 = CR | last3 = Venneri | first3 = A | date = Jun 2009 | title = Individual differences in personality traits reflect structural variance in specific brain regions | journal = Brain Res. Bull. | volume = 79 | issue = 5| pages = 265–70 | doi = 10.1016/j.brainresbull.2009.03.005 | pmid = 19480986 | s2cid = 25490518 }}</ref>


Harm avoidance is a temperament assessed in the [[Temperament and Character Inventory]] (TCI), its revised version (TCI-R) and the [[Tridimensional Personality Questionnaire]] (TPQ) and is positively related to the trait [[neuroticism]] and inversely to [[extraversion]] in the [[Revised NEO Personality Inventory]] and the [[Eysenck Personality Questionnaire]].<ref name=defruyt>{{cite journal|last=De Fruyt|first=F.|coauthors=Van De Wiele, L. & Van Heeringen, C.|title=Cloninger's Psychobiological Model of Temperament and Character and the Five-Factor Model of Personality|journal=Personality and Individual Differences|year=2000|volume=29|pages=441–452|url=http://www.sciencedirect.com/science/article/pii/S0191886999002044|doi=10.1016/S0191-8869(99)00204-4}}</ref> Researchers have contended that harm avoidance represents a composite personality dimension with neurotic introversion at one end of the spectrum and stable extraversion at the other end. Harm avoidance has also been found to have moderate inverse relationships with [[conscientiousness]] and [[openness to experience]] in the [[five factor model]].<ref name=defruyt/>
Harm avoidance is a temperament assessed in the [[Temperament and Character Inventory]] (TCI), its revised version (TCI-R) and the [[Tridimensional Personality Questionnaire]] (TPQ) and is positively related to the trait [[neuroticism]] and inversely to [[extraversion]] in the [[Revised NEO Personality Inventory]] and the [[Eysenck Personality Questionnaire]].<ref name=defruyt>{{cite journal|last=De Fruyt|first=F.|author2=Van De Wiele, L.|author3=Van Heeringen, C.|name-list-style=amp|title=Cloninger's Psychobiological Model of Temperament and Character and the Five-Factor Model of Personality|journal=Personality and Individual Differences|year=2000|volume=29|issue=3|pages=441–452|doi=10.1016/S0191-8869(99)00204-4}}</ref> Researchers have contended that harm avoidance represents a composite personality dimension with neurotic introversion at one end of the spectrum and stable extraversion at the other end. Harm avoidance has also been found to have moderate inverse relationships with [[conscientiousness]] and [[openness to experience]] in the [[five factor model]].<ref name=defruyt/>


The HA of TPQ and TCI-R has four subscales:
The HA of TPQ and TCI-R has four subscales:
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# Fear of uncertainty (HA2)
# Fear of uncertainty (HA2)
# Shyness/Shyness with strangers (HA3)
# Shyness/Shyness with strangers (HA3)
# Fatigability/Fatigability and [[asthenia]] (HA4)
# Fatigability/Fatigability and [[asthenia]] (weakness) (HA4)


It has been suggested that HA is related to high [[serotonin|serotonergic]] activity,<ref>{{Cite journal
It has been suggested that HA is related to high [[serotonin|serotonergic]] activity,<ref>{{Cite journal | author = C. R. Cloninger | title = A unified biosocial theory of personality and its role in the development of anxiety states | journal = Psychiatric Developments | volume = 4 | issue = 3 | pages = 167–226 |date=Autumn 1986 | pmid = 3809156}}</ref>
and much research has gone into investigating the link between HA and components of the serotonin system, e.g. genetic variation in [[5-HTTLPR]] in the [[serotonin transporter]] gene.<ref>{{Cite journal |author1=C. M. Mazzanti |author2=J. Lappalainen |author3=J. C. Long |author4=D. Bengel |author5=H. Naukkarinen |author6=M. Eggert |author7=M. Virkkunen |author8=M. Linnoila |author9=D. Goldman | title = Role of the serotonin transporter promoter polymorphism in anxiety-related traits | journal = Archives of General Psychiatry | volume = 55 | issue = 10 | pages = 936–40 |date=October 1998 | pmid = 9783565 | doi = 10.1001/archpsyc.55.10.936|doi-access=free }}</ref>
| author = C. R. Cloninger
| title = A unified biosocial theory of personality and its role in the development of anxiety states
| journal = Psychiatric Developments
| volume = 4
| issue = 3
| pages = 167–166
|date=Autumn 1986
| pmid = 3809156
}}</ref>
and much research has gone into investigating the link between HA and components of the serotonin system, e.g. genetic variation in [[5-HTTLPR]] in the [[serotonin transporter]] gene.<ref>{{Cite journal
| author = C. M. Mazzanti, J. Lappalainen, J. C. Long, D. Bengel, H. Naukkarinen, M. Eggert, M. Virkkunen, M. Linnoila & D. Goldman
| title = Role of the serotonin transporter promoter polymorphism in anxiety-related traits
| journal = Archives of General Psychiatry
| volume = 55
| issue = 10
| pages = 936–930
|date=October 1998
| pmid = 9783565
| doi = 10.1001/archpsyc.55.10.936
}}</ref>


==References==
==References==
{{reflist|30em}}
{{Reflist}}

{{Psych-stub}}[[Category:Personality traits]]
== External links ==
{{Medical resources
| DiseasesDB =
| ICD10 = {{ICD10|F|60|6|f|60}}
| ICD9 =
| ICDO =
| OMIM =
| MedlinePlus =
| eMedicine_mult =
| MeshID =
}}
[[Category:Personality traits]]

Latest revision as of 05:31, 24 March 2023

Harm avoidance
SpecialtyPsychiatry

Harm avoidance (HA) is a personality trait characterized by excessive worrying; pessimism; shyness; and being fearful, doubtful, and easily fatigued. In MRI studies HA was correlated with reduced grey matter volume in the orbito-frontal, occipital and parietal regions.[1][2]

Harm avoidance is a temperament assessed in the Temperament and Character Inventory (TCI), its revised version (TCI-R) and the Tridimensional Personality Questionnaire (TPQ) and is positively related to the trait neuroticism and inversely to extraversion in the Revised NEO Personality Inventory and the Eysenck Personality Questionnaire.[3] Researchers have contended that harm avoidance represents a composite personality dimension with neurotic introversion at one end of the spectrum and stable extraversion at the other end. Harm avoidance has also been found to have moderate inverse relationships with conscientiousness and openness to experience in the five factor model.[3]

The HA of TPQ and TCI-R has four subscales:

  1. Anticipatory worry (HA1)
  2. Fear of uncertainty (HA2)
  3. Shyness/Shyness with strangers (HA3)
  4. Fatigability/Fatigability and asthenia (weakness) (HA4)

It has been suggested that HA is related to high serotonergic activity,[4] and much research has gone into investigating the link between HA and components of the serotonin system, e.g. genetic variation in 5-HTTLPR in the serotonin transporter gene.[5]

References

[edit]
  1. ^ Cheung, G (Aug 2007). "Stability of the harm avoidance personality trait in late-life depression". Int Psychogeriatr. 19 (4): 778–80. doi:10.1017/s1041610207005194. PMID 17726762.
  2. ^ Gardini, S; Cloninger, CR; Venneri, A (Jun 2009). "Individual differences in personality traits reflect structural variance in specific brain regions". Brain Res. Bull. 79 (5): 265–70. doi:10.1016/j.brainresbull.2009.03.005. PMID 19480986. S2CID 25490518.
  3. ^ a b De Fruyt, F.; Van De Wiele, L. & Van Heeringen, C. (2000). "Cloninger's Psychobiological Model of Temperament and Character and the Five-Factor Model of Personality". Personality and Individual Differences. 29 (3): 441–452. doi:10.1016/S0191-8869(99)00204-4.
  4. ^ C. R. Cloninger (Autumn 1986). "A unified biosocial theory of personality and its role in the development of anxiety states". Psychiatric Developments. 4 (3): 167–226. PMID 3809156.
  5. ^ C. M. Mazzanti; J. Lappalainen; J. C. Long; D. Bengel; H. Naukkarinen; M. Eggert; M. Virkkunen; M. Linnoila; D. Goldman (October 1998). "Role of the serotonin transporter promoter polymorphism in anxiety-related traits". Archives of General Psychiatry. 55 (10): 936–40. doi:10.1001/archpsyc.55.10.936. PMID 9783565.
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