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{{Infobox Disease |
{{Infobox medical condition (new)
| synonyms = Leukoderma acquisitum centrifugum of sutton
Name = Halo nevus |
Image = SkinTumors-281.jpg |
| name = Halo nevus
Caption = |
| image = SkinTumors-281.jpg
DiseasesDB = 8333|
| caption =
|
ICD10 = {{ICD10|I|78|1|i|70}}, D22 ([[ILDS]] D22.L34) |
| pronounce =
ICD9 = {{ICD9|448.1}}, {{ICD9|216.0}}-{{ICD9|216.9}}, {{ICD9|757.32}}|
ICDO = 8723/0|
| field =
OMIM = 234300|
| symptoms =
MedlinePlus = |
| complications =
| onset =
eMedicineSubj = derm|
| duration =
eMedicineTopic = 174|
MeshID = D009508|
| types =
| causes =
| risks =
| diagnosis =
| differential =
| prevention =
| treatment =
| medication =
| prognosis =
| frequency =
| deaths =
}}
}}


'''Halo nevus''' (also known as "Leukoderma acquisitum centrifugum," "Perinevoid vitiligo," and "Sutton nevus"<ref name="Andrews">{{cite book |author=James, William D.; Berger, Timothy G.; et al. |title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |location= |year=2006 |pages= |isbn=0-7216-2921-0 |oclc= |doi= |accessdate=}}</ref>{{rp|689}}) is a [[nevus|mole]] that is surrounded by a [[depigmentation|depigmented]] ring or 'halo'.
'''Halo nevus''' (also known as "Leukoderma acquisitum centrifugum," "Perinevoid vitiligo," and "Sutton nevus"<ref name="Andrews">{{cite book |author1=James, William D. |author2=Berger, Timothy G. |title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |year=2006 |isbn=0-7216-2921-0 |display-authors=etal}}</ref>{{rp|689}}) is a [[nevus|mole]] that is surrounded by a [[depigmentation|depigmented]] ring or 'halo'.


==Causes==
==Presentation==
Halo nevi are also known as Sutton's nevi, or leukoderma acquisitum centrifugum. Halo nevi are named such because they are a mole (nevus) that is surrounded by an area of depigmentation that resembles a halo.
Halo nevi are caused when [[white blood cell|white blood cells]] target a mole. The cause for the attack is unknown.<ref name=skinsite>{{cite web|url=http://www.skinsite.com/info_halo_nevus.htm|title=Halo Nevus - skinsite.com|accessdate=August 4, 2008}}</ref>


Halo nevi are associated with [[vitiligo]]. Sometimes the pale (hypopigmented) areas will spontaneously regress, and pigment returns.
==Predilection==

[[File:Halo_Nevus_zoomed.jpg|thumb|Photograph of a halo nevus on a face]]
==Causes==
Halo nevi are estimated to be present in approximately 1% of the general population, and are found to be more prevalent in people with [[vitiligo]], [[melanoma|malignant melanoma]],<ref name=skinsite/> or [[Turner syndrome]].<ref name=EMed>{{EMedicine|derm|174|Halo Nevis}}</ref> All races and sexes are equally susceptible to this disease, although a familial tendency has been reported. The average age of onset is in a persons teenage years.
The formation of a halo surrounding a nevi is believed to occur when certain [[white blood cell]]s called [[CD8+ T cells|CD8+ T lymphocytes]] destroy the pigment-producing cells of the skin (melanocytes).<ref name=Mundinger>{{cite journal|last=Mundinger|first=Gerhard S.|title=Halo Phenomenon|journal=New England Journal of Medicine|date=January 16, 2014|volume=370|issue=3|pages=262|doi=10.1056/NEJMicm1306230|pmid=24428471}}</ref> The cause for the attack is unknown.<ref name=skinsite>{{cite web|url=http://www.skinsite.com/info_halo_nevus.htm|title=Halo Nevus - skinsite.com|access-date=August 4, 2008}}</ref>
==Diagnosis==
{{Empty section|date=February 2018}}


==Treatment==
==Treatment==
[[File:Halo Nevus zoomed.jpg|thumb|Photograph of a halo nevus on a face]]
As halo nevi are only of cosmetic significance, no treatment is required,<ref>{{cite web|url=http://www.carefair.com/Skincare/Disorders/Halo_Nevus_148.html|title=CareFair.com - Halo Nevis|accessdate=August 4, 2008}}</ref> and patients will be [[asymptomatic]]. Although halo nevi are harmless, it is important to monitor the lesion on regular basis.<ref>{{cite web|url=http://www.dermatalk.com/blogs/skin-disorders/halo-nevus|title=DermaTalk - Halo Nevus}}</ref> Watch out for any changes in appearance of existing or new halo nevi. If there is any change in appearance or is associated with pain, itch, and infection, a doctor should be consulted immediately to exclude the possibility of melanoma.
As halo nevi are only of cosmetic significance, no treatment is required,<ref>{{cite web|url=http://www.carefair.com/Skincare/Disorders/Halo_Nevus_148.html|title=CareFair.com - Halo Nevis|access-date=August 4, 2008}}</ref> and patients will be [[asymptomatic]]. Although halo nevi are harmless, it is important to monitor the lesion on regular basis.<ref>{{cite web|url=http://www.dermatalk.com/blogs/skin-disorders/halo-nevus|title=DermaTalk - Halo Nevus}}</ref> Watch out for any changes in appearance of existing or new halo nevi. If there is any change in appearance or is associated with pain, itch, and infection, a doctor should be consulted immediately to exclude the possibility of melanoma.

==Epidemiology==

Halo nevi are estimated to be present in approximately 1% of the general population, and are found to be more prevalent in people with [[vitiligo]], [[melanoma|malignant melanoma]],<ref name=skinsite/> or [[Turner syndrome]].<ref name=EMed>{{EMedicine|derm|174|Halo Nevis}}</ref> All races and sexes are equally susceptible to this disease, although a familial tendency has been reported. The average age of onset is in a person's teenage years.


==See also==
==See also==
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{{reflist}}
{{reflist}}


==External links==
== External links ==
{{Medical resources
* [http://dermatology.about.com/library/bldefhalonevus.htm Halo Nevus] About.com article
| DiseasesDB = 8333
* [http://thenevus.com thenevus.com] - Halo Nevus Proves Halos Are Not Just For Angels
| ICD10 = {{ICD10|I|78|1|i|70}}, D22 ([[ILDS]] D22.L34)
| ICD9 = {{ICD9|448.1}}, {{ICD9|216.0}}-{{ICD9|216.9}}, {{ICD9|757.32}}
| ICDO = 8723/0
| OMIM = 234300
| MedlinePlus =
| eMedicineSubj = derm
| eMedicineTopic = 174
| MeshID = D009508
}}



{{Skin tumors, nevi and melanomas}}
{{Skin tumors, nevi and melanomas}}

Latest revision as of 21:29, 7 April 2023

Halo nevus
Other namesLeukoderma acquisitum centrifugum of sutton
SpecialtyDermatology Edit this on Wikidata

Halo nevus (also known as "Leukoderma acquisitum centrifugum," "Perinevoid vitiligo," and "Sutton nevus"[1]: 689 ) is a mole that is surrounded by a depigmented ring or 'halo'.

Presentation

[edit]

Halo nevi are also known as Sutton's nevi, or leukoderma acquisitum centrifugum. Halo nevi are named such because they are a mole (nevus) that is surrounded by an area of depigmentation that resembles a halo.

Halo nevi are associated with vitiligo. Sometimes the pale (hypopigmented) areas will spontaneously regress, and pigment returns.

Causes

[edit]

The formation of a halo surrounding a nevi is believed to occur when certain white blood cells called CD8+ T lymphocytes destroy the pigment-producing cells of the skin (melanocytes).[2] The cause for the attack is unknown.[3]

Diagnosis

[edit]

Treatment

[edit]
Photograph of a halo nevus on a face

As halo nevi are only of cosmetic significance, no treatment is required,[4] and patients will be asymptomatic. Although halo nevi are harmless, it is important to monitor the lesion on regular basis.[5] Watch out for any changes in appearance of existing or new halo nevi. If there is any change in appearance or is associated with pain, itch, and infection, a doctor should be consulted immediately to exclude the possibility of melanoma.

Epidemiology

[edit]

Halo nevi are estimated to be present in approximately 1% of the general population, and are found to be more prevalent in people with vitiligo, malignant melanoma,[3] or Turner syndrome.[6] All races and sexes are equally susceptible to this disease, although a familial tendency has been reported. The average age of onset is in a person's teenage years.

See also

[edit]

References

[edit]
  1. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  2. ^ Mundinger, Gerhard S. (January 16, 2014). "Halo Phenomenon". New England Journal of Medicine. 370 (3): 262. doi:10.1056/NEJMicm1306230. PMID 24428471.
  3. ^ a b "Halo Nevus - skinsite.com". Retrieved August 4, 2008.
  4. ^ "CareFair.com - Halo Nevis". Retrieved August 4, 2008.
  5. ^ "DermaTalk - Halo Nevus".
  6. ^ Halo Nevis at eMedicine
[edit]