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{{Short description|Protein-coding gene in the species Homo sapiens}}
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'''snRNA-activating protein complex subunit 1''' is a [[protein]] that in humans is encoded by the ''SNAPC1'' [[gene]].<ref name="pmid9644240">{{cite journal | author = Maeng JH, Yoon JB | title = The human PTFgamma/SNAP43 gene: structure, chromosomal location, and identification of a VNTR in 5'-UTR | journal = J Biochem | volume = 124 | issue = 1 | pages = 23–7 | year = 1998 | month = September | pmid = 9644240 | pmc = | doi = }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6617| accessdate = }}</ref>
{{Infobox_gene}}
'''snRNA-activating protein complex subunit 1''' is a [[protein]] that in humans is encoded by the ''SNAPC1'' [[gene]].<ref name="pmid9644240">{{cite journal |author1=Maeng JH |author2=Yoon JB | title = The human PTFgamma/SNAP43 gene: structure, chromosomal location, and identification of a VNTR in 5'-UTR | journal = J Biochem | volume = 124 | issue = 1 | pages = 23–7 |date=September 1998 | pmid = 9644240 | doi = 10.1093/oxfordjournals.jbchem.a022085}}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6617}}</ref>


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==Interactions==
==Interactions==
SNAPC1 has been shown to [[Protein-protein interaction|interact]] with [[SNAPC4]],<ref name=pmid11056176>{{cite journal |last=Ma |first=B |authorlink= |coauthors=Hernandez N |year=2001|month=February |title=A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc |journal=J. Biol. Chem. |volume=276 |issue=7 |pages=5027–35 |publisher= |location = United States| issn = 0021-9258| pmid = 11056176 |doi = 10.1074/jbc.M009301200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[SNAPC3]]<ref name=pmid11056176/><ref name=pmid9003788>{{cite journal |last=Henry |first=R W |authorlink= |coauthors=Ma B, Sadowski C L, Kobayashi R, Hernandez N |year=1996|month=Dec |title=Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc |journal=EMBO J. |volume=15 |issue=24 |pages=7129–36 |publisher= |location = ENGLAND| issn = 0261-4189| pmid = 9003788 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=452539 }}</ref> and [[Retinoblastoma protein]].<ref name=pmid11094070>{{cite journal |last=Hirsch |first=H A |authorlink= |coauthors=Gu L, Henry R W |year=2000|month=Dec |title=The Retinoblastoma Tumor Suppressor Protein Targets Distinct General Transcription Factors To Regulate RNA Polymerase III Gene Expression |journal=Mol. Cell. Biol. |volume=20 |issue=24 |pages=9182–91 |publisher= |location = UNITED STATES| issn = 0270-7306| pmid = 11094070 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1128/MCB.20.24.9182-9191.2000 |pmc=102176 }}</ref>
SNAPC1 has been shown to [[Protein-protein interaction|interact]] with [[SNAPC4]],<ref name=pmid11056176>{{cite journal |last=Ma |first=B |author2=Hernandez N |date=February 2001 |title=A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc |journal=J. Biol. Chem. |volume=276 |issue=7 |pages=5027–35 |location = United States| issn = 0021-9258| pmid = 11056176 |doi = 10.1074/jbc.M009301200 |doi-access= free}}</ref> [[SNAPC3]]<ref name=pmid11056176/><ref name=pmid9003788>{{cite journal |last=Henry |first=R W |author2=Ma B |author3=Sadowski C L |author4=Kobayashi R |author5=Hernandez N |date=Dec 1996 |title=Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc |journal=EMBO J. |volume=15 |issue=24 |pages=7129–36 |location = ENGLAND|doi=10.1002/j.1460-2075.1996.tb01104.x | issn = 0261-4189| pmid = 9003788 |pmc=452539 }}</ref> and [[Retinoblastoma protein]].<ref name=pmid11094070>{{cite journal |last=Hirsch |first=H A |author2=Gu L |author3=Henry R W |date=Dec 2000 |title=The Retinoblastoma Tumor Suppressor Protein Targets Distinct General Transcription Factors To Regulate RNA Polymerase III Gene Expression |journal=Mol. Cell. Biol. |volume=20 |issue=24 |pages=9182–91 |location = UNITED STATES| issn = 0270-7306| pmid = 11094070 |doi=10.1128/MCB.20.24.9182-9191.2000 |pmc=102176 }}</ref>


==References==
==References==
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==Further reading==
==Further reading==
{{Refbegin | 2}}
{{Refbegin | 2}}
*{{cite journal |author1=Henry RW |author2=Sadowski CL |author3=Kobayashi R |author4=Hernandez N |title=A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III |journal=Nature |volume=374 |issue= 6523 |pages= 653–6 |year= 1995 |pmid= 7715707 |doi= 10.1038/374653a0 |bibcode=1995Natur.374..653H |s2cid=4325527 }}
{{PBB_Further reading
*{{cite journal |author1=Yoon JB |author2=Roeder RG |title=Cloning of two proximal sequence element-binding transcription factor subunits (gamma and delta) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein |journal=Mol. Cell. Biol. |volume=16 |issue= 1 |pages= 1–9 |year= 1996 |pmid= 8524284 |doi=10.1016/S1569-2558(08)60061-2 | pmc=230972 | series=Advances in Molecular and Cell Biology | isbn=978-0-7623-0143-0 }}
| citations =
*{{cite journal | author=Henry RW, Sadowski CL, Kobayashi R, Hernandez N |title=A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III |journal=Nature |volume=374 |issue= 6523 |pages= 653–6 |year= 1995 |pmid= 7715707 |doi= 10.1038/374653a0 }}
*{{cite journal |vauthors=Henry RW, Ma B, Sadowski CL, etal |title=Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc |journal=EMBO J. |volume=15 |issue= 24 |pages= 7129–36 |year= 1997 |doi=10.1002/j.1460-2075.1996.tb01104.x |pmid= 9003788 | pmc=452539 }}
*{{cite journal | author=Yoon JB, Roeder RG |title=Cloning of two proximal sequence element-binding transcription factor subunits (gamma and delta) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein |journal=Mol. Cell. Biol. |volume=16 |issue= 1 |pages= 1–9 |year= 1996 |pmid= 8524284 |doi=10.1016/S1569-2558(08)60061-2 | pmc=230972 | series=Advances in Molecular and Cell Biology | isbn=978-0-7623-0143-0 }}
*{{cite journal |author1=Ma B |author2=Hernandez N |title=A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc |journal=J. Biol. Chem. |volume=276 |issue= 7 |pages= 5027–35 |year= 2001 |pmid= 11056176 |doi= 10.1074/jbc.M009301200 |doi-access= free}}
*{{cite journal | author=Henry RW, Ma B, Sadowski CL, ''et al.'' |title=Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc |journal=EMBO J. |volume=15 |issue= 24 |pages= 7129–36 |year= 1997 |pmid= 9003788 |doi= | pmc=452539 }}
*{{cite journal |author1=Hirsch HA |author2=Gu L |author3=Henry RW |title=The Retinoblastoma Tumor Suppressor Protein Targets Distinct General Transcription Factors To Regulate RNA Polymerase III Gene Expression |journal=Mol. Cell. Biol. |volume=20 |issue= 24 |pages= 9182–91 |year= 2001 |pmid= 11094070 |doi=10.1128/MCB.20.24.9182-9191.2000 | pmc=102176 }}
*{{cite journal | author=Ma B, Hernandez N |title=A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc |journal=J. Biol. Chem. |volume=276 |issue= 7 |pages= 5027–35 |year= 2001 |pmid= 11056176 |doi= 10.1074/jbc.M009301200 }}
*{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
*{{cite journal | author=Hirsch HA, Gu L, Henry RW |title=The Retinoblastoma Tumor Suppressor Protein Targets Distinct General Transcription Factors To Regulate RNA Polymerase III Gene Expression |journal=Mol. Cell. Biol. |volume=20 |issue= 24 |pages= 9182–91 |year= 2001 |pmid= 11094070 |doi=10.1128/MCB.20.24.9182-9191.2000 | pmc=102176 }}
*{{cite journal |vauthors=Hinkley CS, Hirsch HA, Gu L, etal |title=The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition |journal=J. Biol. Chem. |volume=278 |issue= 20 |pages= 18649–57 |year= 2003 |pmid= 12621023 |doi= 10.1074/jbc.M204247200 |doi-access= free }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Hinkley CS, Hirsch HA, Gu L, ''et al.'' |title=The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition |journal=J. Biol. Chem. |volume=278 |issue= 20 |pages= 18649–57 |year= 2003 |pmid= 12621023 |doi= 10.1074/jbc.M204247200 }}
*{{cite journal |author1=Gu L |author2=Esselman WJ |author3=Henry RW |title=Cooperation between small nuclear RNA-activating protein complex (SNAPC) and TATA-box-binding protein antagonizes protein kinase CK2 inhibition of DNA binding by SNAPC |journal=J. Biol. Chem. |volume=280 |issue= 30 |pages= 27697–704 |year= 2005 |pmid= 15955816 |doi= 10.1074/jbc.M503206200 |doi-access=free }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R |s2cid=4427026 }}
*{{cite journal | author=Gu L, Esselman WJ, Henry RW |title=Cooperation between small nuclear RNA-activating protein complex (SNAPC) and TATA-box-binding protein antagonizes protein kinase CK2 inhibition of DNA binding by SNAPC |journal=J. Biol. Chem. |volume=280 |issue= 30 |pages= 27697–704 |year= 2005 |pmid= 15955816 |doi= 10.1074/jbc.M503206200 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
}}
{{Refend}}
{{Refend}}


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Latest revision as of 07:27, 7 January 2024

SNAPC1
Identifiers
AliasesSNAPC1, PTFgamma, SNAP43, small nuclear RNA activating complex polypeptide 1
External IDsOMIM: 600591; MGI: 1922877; HomoloGene: 2317; GeneCards: SNAPC1; OMA:SNAPC1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003082

NM_178392

RefSeq (protein)

NP_003073

NP_848479

Location (UCSC)Chr 14: 61.76 – 61.8 MbChr 12: 74.01 – 74.04 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

snRNA-activating protein complex subunit 1 is a protein that in humans is encoded by the SNAPC1 gene.[5][6]


Interactions

[edit]

SNAPC1 has been shown to interact with SNAPC4,[7] SNAPC3[7][8] and Retinoblastoma protein.[9]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000023608Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021113Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Maeng JH, Yoon JB (September 1998). "The human PTFgamma/SNAP43 gene: structure, chromosomal location, and identification of a VNTR in 5'-UTR". J Biochem. 124 (1): 23–7. doi:10.1093/oxfordjournals.jbchem.a022085. PMID 9644240.
  6. ^ "Entrez Gene: SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa".
  7. ^ a b Ma B, Hernandez N (February 2001). "A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc". J. Biol. Chem. 276 (7). United States: 5027–35. doi:10.1074/jbc.M009301200. ISSN 0021-9258. PMID 11056176.
  8. ^ Henry RW, Ma B, Sadowski C L, Kobayashi R, Hernandez N (Dec 1996). "Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc". EMBO J. 15 (24). ENGLAND: 7129–36. doi:10.1002/j.1460-2075.1996.tb01104.x. ISSN 0261-4189. PMC 452539. PMID 9003788.
  9. ^ Hirsch HA, Gu L, Henry R W (Dec 2000). "The Retinoblastoma Tumor Suppressor Protein Targets Distinct General Transcription Factors To Regulate RNA Polymerase III Gene Expression". Mol. Cell. Biol. 20 (24). UNITED STATES: 9182–91. doi:10.1128/MCB.20.24.9182-9191.2000. ISSN 0270-7306. PMC 102176. PMID 11094070.

Further reading

[edit]