Hepatokine: Difference between revisions
Content deleted Content added
W. C. Minor (talk | contribs) m etymology |
W. C. Minor (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
'''Hepatokines''' (Greek ''heapto-'', liver; and ''-kinos'', movement) are [[protein]]s produced by [[liver]] cells ([[hepatocyte]]s) that are [[Secretion|secreted]] into the circulation and function as [[hormone]]s across the organism. Research is mostly focused on hepatokines that play role in the regulation of metabolic diseases such as [[diabetes]] and [[Fatty liver disease|fatty liver]] including: [[Adropin]], [[ANGPTL4]], [[Fetuin-A]], [[Fetuin-B]], [[FGF21|FGF-21]], [[Hepassocin]], [[LECT2]], [[Retinol binding protein 4|RBP4]][[Selenoprotein P|,Selenoprotein P,]] [[Sex hormone-binding globulin]].<ref>{{Cite journal |last=Meex |first=Ruth C. R. |last2=Watt |first2=Matthew J. |date=September 2017 |title=Hepatokines: linking nonalcoholic fatty liver disease and insulin resistance |url=https://www.nature.com/articles/nrendo.2017.56 |journal=Nature Reviews Endocrinology |language=en |volume=13 |issue=9 |pages=509–520 |doi=10.1038/nrendo.2017.56 |issn=1759-5037}}</ref> |
'''Hepatokines''' (Greek ''heapto-'', liver; and ''-kinos'', movement) are [[protein]]s produced by [[liver]] cells ([[hepatocyte]]s) that are [[Secretion|secreted]] into the [[Circulatory system|circulation]] and function as [[hormone]]s across the organism. Research is mostly focused on hepatokines that play role in the regulation of metabolic diseases such as [[diabetes]] and [[Fatty liver disease|fatty liver]] including: [[Adropin]], [[ANGPTL4]], [[Fetuin-A]], [[Fetuin-B]], [[FGF21|FGF-21]], [[Hepassocin]], [[LECT2]], [[Retinol binding protein 4|RBP4]][[Selenoprotein P|,Selenoprotein P,]] [[Sex hormone-binding globulin]].<ref>{{Cite journal |last=Meex |first=Ruth C. R. |last2=Watt |first2=Matthew J. |date=September 2017 |title=Hepatokines: linking nonalcoholic fatty liver disease and insulin resistance |url=https://www.nature.com/articles/nrendo.2017.56 |journal=Nature Reviews Endocrinology |language=en |volume=13 |issue=9 |pages=509–520 |doi=10.1038/nrendo.2017.56 |issn=1759-5037}}</ref> |
||
== See also == |
== See also == |
||
Revision as of 14:32, 15 August 2022
Hepatokines (Greek heapto-, liver; and -kinos, movement) are proteins produced by liver cells (hepatocytes) that are secreted into the circulation and function as hormones across the organism. Research is mostly focused on hepatokines that play role in the regulation of metabolic diseases such as diabetes and fatty liver including: Adropin, ANGPTL4, Fetuin-A, Fetuin-B, FGF-21, Hepassocin, LECT2, RBP4,Selenoprotein P, Sex hormone-binding globulin.[1]
See also
References
- ^ Meex, Ruth C. R.; Watt, Matthew J. (September 2017). "Hepatokines: linking nonalcoholic fatty liver disease and insulin resistance". Nature Reviews Endocrinology. 13 (9): 509–520. doi:10.1038/nrendo.2017.56. ISSN 1759-5037.