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Seed's DS-01™ underwent four clinical trials regarding 'constipation, post-alcohol gut microbiota restoration, urolithin production, and recovery after broad-spectrum antibiotics'.<ref>{{Cite web |title=On the hunt for bugs outside the gut, Seed Health snares $40M round to advance pipeline with the help of George Church |url=https://endpts.com/on-the-hunt-for-bugs-outside-the-gut-seed-health-snares-40m-round-to-advance-pipeline-with-the-help-of-george-church/ |access-date=2022-07-14 |website=Endpoints News |language=en}}</ref> The company's first live biotherapeutic entered FDA and EMA trials in 2021 for Urinary Tract Infections (UTIs).<ref>{{Cite web |last=Health |first=Seed |title=Seed Health Closes $40 Million in Series A Financing to Launch New Categories, Accelerate Global Distribution and Expand Clinical Research |url=https://www.prnewswire.com/il/news-releases/seed-health-closes-40-million-in-series-a-financing-to-launch-new-categories-accelerate-global-distribution-and-expand-clinical-research-851350899.html |access-date=2022-07-14 |website=www.prnewswire.com |language=en}}</ref>
Seed's DS-01™ underwent four clinical trials regarding 'constipation, post-alcohol gut microbiota restoration, urolithin production, and recovery after broad-spectrum antibiotics'.<ref>{{Cite web |title=On the hunt for bugs outside the gut, Seed Health snares $40M round to advance pipeline with the help of George Church |url=https://endpts.com/on-the-hunt-for-bugs-outside-the-gut-seed-health-snares-40m-round-to-advance-pipeline-with-the-help-of-george-church/ |access-date=2022-07-14 |website=Endpoints News |language=en}}</ref> The company's first live biotherapeutic entered FDA and EMA trials in 2021 for Urinary Tract Infections (UTIs).<ref>{{Cite web |last=Health |first=Seed |title=Seed Health Closes $40 Million in Series A Financing to Launch New Categories, Accelerate Global Distribution and Expand Clinical Research |url=https://www.prnewswire.com/il/news-releases/seed-health-closes-40-million-in-series-a-financing-to-launch-new-categories-accelerate-global-distribution-and-expand-clinical-research-851350899.html |access-date=2022-07-14 |website=www.prnewswire.com |language=en}}</ref>

== References ==
{{reflist|30em}}{{reflist|30em}}

Revision as of 20:07, 15 September 2022

Seed Health, popularly known as Seed, is an American health and life science company, known for its line of probiotics. Founded in 2015 by Ara Katz and Raja Dhir, Seed was launched with the aim to 'impact human and planetary health'. The company has two flagship products; their DS-01™ Daily Synbiotic, and PDS-08™ Pediatric Daily Synbiotic. Both are sold direct to consumer, forgoing traditional brick-and-mortar retail.

Seed develops products aided by partnerships with academic institutions including Caltech, Harvard University, MIT, the University of Zurich and Stanford University. The company is set to expand into developing skincare, oral care and infant health, alongside developing solutions to ecological challenges with SeedLabs.

History

Seed was founded in Los Angeles in 2015 and incorporated as Seed Health, Inc. to operate as a microbial sciences company, serving the US market.[1] Bloomberg notes their initial focus on discoveries across 'novel therapeutics, consumer health innovations, and environmental solutions'.[2]

It's founders and Co-CEOs are consumer tech entrepreneur Ara Katz and microbiome entrepreneur Raja Dhir.[3] Katz previously co-founded mobile commerce company, Spring, and is a fellow at the MIT Media Lab.[4][5][6] Dhir served on the board of scientific journal, Microbiome, alongside developing prior microbiome patents.[7][8]

In February 2021, the company announced it had acquired New York-based Auggi Technologies Inc., using artificial intelligence to track and analyze digestive health.[9] In July 2022, Seed partnered with Axial Therapeutics to "develop probiotics and therapeutics that [...] target anxiety, depression and mental wellbeing".[10]

As of 2022, Seed has 92 employees.[11] The company's research partners include Caltech, Harvard University, MIT, University of Zurich, Stanford University, Mass General Hospital, and Cleveland Clinic.[12][13] In 2022, Seed appointed Dirk Gevers, Former head of J&J's Janssen Human Microbiome Institute, as Chief Scientific Officer.[14][15]

Leadership structure

Seed is led by Dhir and Katz as co-CEOs, and advised by a board of Caltech Microbiology Professor Sarkis Mazmanian and Investor Ernesto Schmitt.[16][17] Dhir leads Seed's research, academic collaborations and scientific side.[18]

Seed's Scientific Advisory Board is led by Dhir and includes Dr. Jacques Ravel, Director of the Institute for Genome Sciences at the University of Maryland, Dr. Gregor Reid, Director of the Canadian R&D Centre for Human Microbiome and Probiotics, Dr. George M. Church and Robert Winthrop Professor of Genetics at Harvard Medical School and Professor of Health Sciences and Technology at Harvard and MIT.[19]

SeedLabs and others

In 2018, Seed established SeedLabs to develop solutions to ecological and environmental challenges using microbes. SeedLabs' developments include a probiotic for honeybees, featured in Time Magazine's 2018 best inventions, and as a Fast Company 'World Changing Idea'.[20][21] SeedLabs also focuses on applying probiotic solutions to coral regeneration, biomaterial development, and space.[22]

Funding and revenue

Seed had seed rounds in 2017 and 2019. Their Series A raised $40m, including $32.5m from The Craftory, with the remainder from and Artis Ventures and other contributing VCs.[23][24][25] Other backers include Cameron Diaz, Jessica Biel and Karlie Kloss.[26][27] In 2021, Seed estimated the probiotics market as worth $57.2 billion, and WWD quoted Seed as "on track" for a 8,948 percent three-year growth rate by the end of the second quarter 2021.[25][28] The Series A funding was used to grow the Seed team, and to 'go beyond the gut', developing skincare, oral care and infant health, and to fund an international expansion.[29] The company was said to be interested in an Asia-Pacific region expansion, where the market was projected to have a 46 percent rate of growth over the following five years.[25]

Products and distribution

Seed has two flagship products. Their DS-01™ Daily Synbiotic, formulated for gut, digestive and immune benefits, and their PDS-08™ Pediatric Daily Synbiotic.[30][31][32] The former comes in refillable capsule form, while the latter comes in powdered sachet form.[33][34]

Seed sells both products, which are vegan, on a 30-day, refillable, supply model.[35][36] Initial purchases come with a refillable glass jar or aluminium capsule, and subsequent purchases are sent in biodegradable, plastic-free packaging.[36] In 2021, Seed announced to Fast Company Magazine that they were carbon-negative, and released an 80-page field-guide to aide companies in becoming carbon negative.[37]

Product lines

  • DS-01™ Daily Synbiotic; a 24-strain broad spectrum probiotic with IND authorisation for a clinical trial on IBS patients under Dr. Anthony Lembo at Harvard Medical School.
  • PDS-08™ Pediatric Daily Synbiotic; a pre- and probiotic developed for under 18s, and launched in 2022.

Seed's DS-01™ underwent four clinical trials regarding 'constipation, post-alcohol gut microbiota restoration, urolithin production, and recovery after broad-spectrum antibiotics'.[38] The company's first live biotherapeutic entered FDA and EMA trials in 2021 for Urinary Tract Infections (UTIs).[39]

References

  1. ^ "Seed Health". CNBC. 12 Nov 2019. Retrieved 14 Jul 2022.
  2. ^ "Seed Health Inc". Bloomberg L.P. p. 1. Seed Health, Inc. operates as a microbial sciences company. The Company focuses on discoveries in microbial sciences across a pipeline of novel therapeutics, consumer health innovations, and environmental solutions. Seed Health serves customers in the United States.
  3. ^ "Microbiome Company Seed™ Launches to Disrupt Probiotics, Set New Industry Standards". Bloomberg.com. 2018-06-06. Retrieved 2022-07-14.
  4. ^ Staff (2016-02-12). "Spring App Co-Founder Ara Katz's Abbot Kinney Loft (Photos)". The Hollywood Reporter. Retrieved 2022-07-14.
  5. ^ Stanger, Maya Kosoff, Emmie Martin, Melissa. "SILICON ALLEY 100: Meet the most inspiring and influential people in New York tech right now". Business Insider. Retrieved 2022-07-14.{{cite web}}: CS1 maint: multiple names: authors list (link)
  6. ^ Ryan, Emily. "Ara Katz Suggests You Listen to Your Gut". DuJour Media.
  7. ^ Quaglia, Sofia. "How your microbiome can improve your health". www.bbc.com. Retrieved 2022-07-14.
  8. ^ DeAngelis, Allison. "See the presentation microbiome startup Seed Health used to raise $40 million". Business Insider. Retrieved 2022-07-14.
  9. ^ "Cornell Tech - Auggi Acquired by Seed Health". Cornell Tech. 2021-02-09. Retrieved 2022-07-14.
  10. ^ nutraingredients.com. "Seed Health partners with Axial Therapeutics for gut-brain program". nutraingredients.com. Retrieved 2022-07-17.
  11. ^ "Seed Health". Craft Co.
  12. ^ "Seed Health Appoints Former Head of J&J's Janssen Human Microbiome Institute, Dirk Gevers, as Chief Scientific Officer". finance.yahoo.com. Retrieved 2022-07-14.
  13. ^ "Center for Computational and Integrative Biology". ccib.mgh.harvard.edu. Retrieved 2022-07-14.
  14. ^ Health, Seed. "Seed Health Appoints Former Head of J&J's Janssen Human Microbiome Institute, Dirk Gevers, as Chief Scientific Officer". www.prnewswire.com. Retrieved 2022-07-14.
  15. ^ "Seed Health Taps Former Head of J&J's Janssen Human Microbiome Institute To Lead R&D". HAPPI. Retrieved 2022-07-14.
  16. ^ "Summit News | Ara Katz is Using Microbes to Improve Human and Planetary Health". summit.co. Retrieved 2022-07-14.
  17. ^ "Seed Health - Crunchbase Investor Profile & Investments". Crunchbase. Retrieved 2022-07-14.
  18. ^ "Raja Dhir - Co-Founder and Co-CEO @ Seed Health - Crunchbase Person Profile". Crunchbase. Retrieved 2022-07-14.
  19. ^ Gross, Rachel E. (2022-04-27). "Can Probiotics Boost Vaginal Health?". The New York Times. ISSN 0362-4331. Retrieved 2022-07-14.
  20. ^ "Health Food for Sick Bees: Honorable Mention on Best Inventions of 2018". Time. Retrieved 2022-07-14.
  21. ^ Peters, Adele (2018-08-27). "These probiotics for bees are designed to boost insect immune systems". Fast Company. Retrieved 2022-07-14.
  22. ^ Peters, Adele (2022-05-03). "How healthy bacteria could protect coral reefs from climate change". Fast Company. Retrieved 2022-07-14.
  23. ^ DeAngelis, Allison. "See the presentation microbiome startup Seed Health used to raise $40 million". Business Insider. Retrieved 2022-07-14.
  24. ^ "Seed Investment Page". The Craftory. Retrieved 2022-07-14.
  25. ^ a b c "Seed Health Secures $40 Million in Series A Funding". finance.yahoo.com. Retrieved 2022-07-14. The first area of interest is the Asia-Pacific region, where the market is projected to have a 46 percent global growth rate in the next five years, according to the company.
  26. ^ Strick, Katie (2019-08-19). "Seed is the new probiotic backed by Cameron Diaz and Jessica Biel". Evening Standard. Retrieved 2022-07-14.
  27. ^ Brodwin, Erin. "A new kind of probiotic could change the $38 billion market by using real science". Business Insider. Retrieved 2022-07-14.
  28. ^ Chikhoune, Ryma; Chikhoune, Ryma (2021-04-21). "Seed Health Secures $40 Million in Series A Funding". WWD. Retrieved 2022-07-14. The probiotics market is worth an estimated $57.2 billion, according to Seed Health, which is "on track" for a 8,948 percent three-year growth rate by the end of the second quarter this year.
  29. ^ "Seed's New $40M in Funding Will Let It 'Go Beyond the Gut'". dot.LA. 2021-04-22. Retrieved 2022-07-14.
  30. ^ Media, Our Partners at Verma (2022-05-10). "19 Best Probiotics for Women In 2022 Los Angeles Magazine". Los Angeles Magazine. Retrieved 2022-07-14.
  31. ^ "Reinforce Your Gut Health With Science-Backed Probiotics". Futurism. Retrieved 2022-07-14.
  32. ^ "What the ELLE Canada Team Is Loving Right Now". Elle Canada. Retrieved 2022-07-14.
  33. ^ Nast, Condé (2022-03-14). "The Bedtime Essentials and Rituals of 24 Beauty and Wellness Experts". Architectural Digest. Retrieved 2022-07-14.
  34. ^ Group, By Blue Ribbon (2022-06-10). "The 5 Best Probiotic Supplements In 2022: Top 5 Gut Health Supplements". D Magazine. Retrieved 2022-07-14. The brand produced PSD-08 Pediatric Daily Synbiotic for kids and teenagers. The formulation is made into powder form and packed in sachets.
  35. ^ Wilson, Angelica (2022-02-04). "This Daily Synbiotic Helped Me Get My Sh*t Together". POPSUGAR Fitness. Retrieved 2022-07-14.
  36. ^ a b "Seed Makes An Impact On Human & Planetary Health". www.thedieline.com. Retrieved 2022-07-14. sustainable refill system
  37. ^ Toussaint, Kristin (2021-04-30). "This field guide teaches companies how they can go carbon negative". Fast Company. Retrieved 2022-07-14.
  38. ^ "On the hunt for bugs outside the gut, Seed Health snares $40M round to advance pipeline with the help of George Church". Endpoints News. Retrieved 2022-07-14.
  39. ^ Health, Seed. "Seed Health Closes $40 Million in Series A Financing to Launch New Categories, Accelerate Global Distribution and Expand Clinical Research". www.prnewswire.com. Retrieved 2022-07-14.
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