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{{Short description|American radiologist and physician}}
{{Short description|American radiologist and physician}}
{{Infobox person/Wikidata | fetchwikidata=ALL}}
{{Infobox person/Wikidata | fetchwikidata=ALL}}
{{Use mdy dates|date=June 2024}}


'''Rachel F. Brem''', MD, FACR, FSBI, is an American [[radiologist|diagnostic radiologist]], professor of radiology at the George Washington University School of Medicine & Health Sciences, and director of the Breast Imaging and Interventional Center at George Washington University’s Cancer Center. She previously served as director of [[Breast imaging|Breast Imaging]] at [[Johns Hopkins Hospital|Johns Hopkins]].<ref name="GW">{{cite web |title=Rachel Brem, MD |url=https://gwdocs.com/profile/rachel-brem |website=GW Medical Faculty Associates |access-date=5 May 2024}}</ref><ref name="SPM">{{cite web |title=Dr Rachel Brem |url=https://screenpoint-medical.com/management-staff/dr-rachel-brem/ |website=Screen Point Medical |access-date=5 May 2024}}</ref> Brem develops novel technologies to better support early [[Breast cancer screening|diagnosis]] and [[Breast cancer management|treatment]] of [[breast cancer]].<ref name="Chabad"/> She is a fellow of the [[American College of Radiology]] and the [[Society of Breast Imaging]].<ref name="Alliance"/>
'''Rachel F. Brem''', MD, FACR, FSBI, is an American [[radiologist|diagnostic radiologist]], professor of radiology at the George Washington University School of Medicine & Health Sciences, and director of the Breast Imaging and Interventional Center at George Washington University’s Cancer Center. She previously served as director of [[Breast imaging|Breast Imaging]] at [[Johns Hopkins Hospital|Johns Hopkins]].<ref name="GW">{{cite web |title=Rachel Brem, MD |url=https://gwdocs.com/profile/rachel-brem |website=GW Medical Faculty Associates |access-date=May 5, 2024}}</ref><ref name="SPM">{{cite web |title=Dr Rachel Brem |url=https://screenpoint-medical.com/management-staff/dr-rachel-brem/ |website=Screen Point Medical |access-date=May 5, 2024}}</ref> Brem develops novel technologies to better support early [[Breast cancer screening|diagnosis]] and [[Breast cancer management|treatment]] of [[breast cancer]].<ref name="Chabad"/> She is a fellow of the [[American College of Radiology]] and the [[Society of Breast Imaging]].<ref name="Alliance"/>


==Early life and education==
==Early life and education==
Rachel Frydman was born to Mechel Frydman and Lea Fishman, of [[Glen Rock, New Jersey]].<ref name="engagement">{{cite news |title=Henry Brem Fiance Of Rachel Frydman |url=https://www.nytimes.com/1977/03/20/archives/henry-brem-fiance-of-rachel-frydman.html |work=The New York Times |date=20 March 1977}}</ref><ref>{{Cite web |title=Mechel Frydman Obituary (2015) - Pikesville, MD - Concord Monitor |url=https://www.legacy.com/us/obituaries/concordmonitor/name/mechel-frydman-obituary?id=18154360 |access-date=2024-05-06 |website=Legacy.com}}</ref> From a young age, Rachel wanted to be a doctor, a decision that was reinforced when her mother, Lea Frydman, was diagnosed with breast cancer when Brem was 12 years old. Despite being given only six months to live, Lea went on to survive breast and ovarian cancer and live for another 44 years.<ref name="Bergel"/>
Rachel Frydman was born to Mechel Frydman and Lea Fishman, of [[Glen Rock, New Jersey]].<ref name="engagement">{{cite news |title=Henry Brem Fiance Of Rachel Frydman |url=https://www.nytimes.com/1977/03/20/archives/henry-brem-fiance-of-rachel-frydman.html |work=The New York Times |date=March 20, 1977}}</ref><ref>{{Cite web |title=Mechel Frydman Obituary (2015) - Pikesville, MD - Concord Monitor |url=https://www.legacy.com/us/obituaries/concordmonitor/name/mechel-frydman-obituary?id=18154360 |access-date=May 6, 2024 |website=Legacy.com}}</ref> From a young age, Rachel wanted to be a doctor, a decision that was reinforced when her mother, Lea Frydman, was diagnosed with breast cancer when Brem was 12 years old. Despite being given only six months to live, Lea went on to survive breast and ovarian cancer and live for another 44 years.<ref name="Bergel"/>


Rachel became engaged to [[Henry Brem]], then a medical student, while she was a student at Brandeis.<ref name="engagement"/>
Rachel became engaged to [[Henry Brem]], then a medical student, while she was a student at Brandeis.<ref name="engagement"/>
Rachel Brem received a B.A. from [[Brandeis University]] in 1979. She then went to [[Columbia University]]'s medical school, graduating with honors in 1984.<ref name="dates">{{cite web |title=Rachel Brem, MD |url=https://cancercenter.gwu.edu/profile/rachel-brem |website=GW Cancer Center}}</ref><ref name="Alliance">{{cite news |title=We are proud to welcome two new members of our medical advisory board: Dr. Rachel Brem and Dr. Eleni Tousimis |url=https://breastcanceralliance.org/ckfinder/connector?command=Proxy&type=Files&currentFolder=%2F&fileName=BCA_Outlook_Fall_2018+(002)(1).pdf&cache=31536000 |access-date=5 May 2024 |work=Outlook|page=4| volume= 24 |issue= 2 |publisher=Breast Cancer Alliance |date=2018}}</ref> Brem completed an internship in internal medicine at [[Sinai Hospital of Baltimore]]<ref name="Breathe">{{cite news |title=Breathe BioMedical announces new Executive Director |url=https://www.canadianmanufacturing.com/manufacturing/breathe-biomedical-announces-new-executive-director-296943/ |access-date=5 May 2024 |work=Canadian Manufacturing |date=9 January 2024}}</ref> (1984–1985<ref>{{cite web |title=Dr. Rachel F. Brem MD |url=https://health.usnews.com/doctors/rachel-brem-4997 |website=US News Health}}</ref>), and a residency in diagnostic radiology (1985–1989) and a fellowship in breast imaging (1989–1990) at Johns Hopkins. She holds board certification in [[diagnostic radiology]].<ref name="CC">{{cite web |title=Dr. Rachel F. Brem - Diagnostic Radiology - Washington, DC |url=https://www.castleconnolly.com/top-doctors/rachel-f-brem-diagnostic-radiology-16cc000139 |website=Castle Connolly |access-date=5 May 2024}}</ref>
Rachel Brem received a B.A. from [[Brandeis University]] in 1979. She then went to [[Columbia University]]'s medical school, graduating with honors in 1984.<ref name="dates">{{cite web |title=Rachel Brem, MD |url=https://cancercenter.gwu.edu/profile/rachel-brem |website=GW Cancer Center}}</ref><ref name="Alliance">{{cite news |title=We are proud to welcome two new members of our medical advisory board: Dr. Rachel Brem and Dr. Eleni Tousimis |url=https://breastcanceralliance.org/ckfinder/connector?command=Proxy&type=Files&currentFolder=%2F&fileName=BCA_Outlook_Fall_2018+(002)(1).pdf&cache=31536000 |access-date=May 5, 2024 |work=Outlook|page=4| volume= 24 |issue= 2 |publisher=Breast Cancer Alliance |date=2018}}</ref> Brem completed an internship in internal medicine at [[Sinai Hospital of Baltimore]]<ref name="Breathe">{{cite news |title=Breathe BioMedical announces new Executive Director |url=https://www.canadianmanufacturing.com/manufacturing/breathe-biomedical-announces-new-executive-director-296943/ |access-date=May 5, 2024 |work=Canadian Manufacturing |date=January 9, 2024}}</ref> (1984–1985<ref>{{cite web |title=Dr. Rachel F. Brem MD |url=https://health.usnews.com/doctors/rachel-brem-4997 |website=US News Health}}</ref>), and a residency in diagnostic radiology (1985–1989) and a fellowship in breast imaging (1989–1990) at Johns Hopkins. She holds board certification in [[diagnostic radiology]].<ref name="CC">{{cite web |title=Dr. Rachel F. Brem - Diagnostic Radiology - Washington, DC |url=https://www.castleconnolly.com/top-doctors/rachel-f-brem-diagnostic-radiology-16cc000139 |website=Castle Connolly |access-date=May 5, 2024}}</ref>


In the mid-1990s, researchers discovered that [[Ashkenazi Jewish]] families were at higher risk for breast cancer due to the [[BRCA mutation]]. In 1996, after a maternal aunt had also been diagnosed with breast cancer, Brem chose to be tested for the gene. It was detected, and she scheduled a [[radical mastectomy]] on the basis of her genetic results. Ironically, she subsequently detected the presence of an existing tumor in her breast while testing [[Breast ultrasound|ultrasound equipment]] for her hospital.<ref name="Bergel">{{cite news |last1=Bergel |first1=Tori |title=The Washington doctors helping women navigate breast cancer |url=https://jewishinsider.com/2023/06/dr-rachel-brem-dr-christy-teal-breast-cancer-no-longer-radical/ |access-date=5 May 2024 |work=Jewish Insider |date=7 June 2023 |quote="In a twist of fate, Brem discovered her own breast cancer while testing new ultrasound equipment at the hospital."}}</ref><ref name="Teal">{{cite book |last1=Brem |first1=Rachel |last2=Teal |first2=Christy |title=No Longer Radical: Understanding Mastectomies and Choosing the Breast Cancer Care That's Right For You |date=16 May 2023 |publisher=Simon and Schuster |isbn=978-1-6680-0115-8 |url=https://books.google.com/books?id=7UyUEAAAQBAJ&q=Newsweek:+2015+rachel+brem}}</ref> Brem strongly recommends early testing for women who are of Ashkenazi Jewish descent or who have a family history of breast cancer.<ref name="Bergel"/>
In the mid-1990s, researchers discovered that [[Ashkenazi Jewish]] families were at higher risk for breast cancer due to the [[BRCA mutation]]. In 1996, after a maternal aunt had also been diagnosed with breast cancer, Brem chose to be tested for the gene. It was detected, and she scheduled a [[radical mastectomy]] on the basis of her genetic results. Ironically, she subsequently detected the presence of an existing tumor in her breast while testing [[Breast ultrasound|ultrasound equipment]] for her hospital.<ref name="Bergel">{{cite news |last1=Bergel |first1=Tori |title=The Washington doctors helping women navigate breast cancer |url=https://jewishinsider.com/2023/06/dr-rachel-brem-dr-christy-teal-breast-cancer-no-longer-radical/ |access-date=May 5, 2024 |work=Jewish Insider |date=June 7, 2023 |quote="In a twist of fate, Brem discovered her own breast cancer while testing new ultrasound equipment at the hospital."}}</ref><ref name="Teal">{{cite book |last1=Brem |first1=Rachel |last2=Teal |first2=Christy |title=No Longer Radical: Understanding Mastectomies and Choosing the Breast Cancer Care That's Right For You |date=May 16, 2023 |publisher=Simon and Schuster |isbn=978-1-6680-0115-8 |url=https://books.google.com/books?id=7UyUEAAAQBAJ&q=Newsweek:+2015+rachel+brem}}</ref> Brem strongly recommends early testing for women who are of Ashkenazi Jewish descent or who have a family history of breast cancer.<ref name="Bergel"/>


==Career==
==Career==
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In 2000, Brem moved to [[George Washington University]] (GWU) where she became a Professor of Radiology at the George Washington University School of Medicine & Health Sciences.<ref name="GW"/><ref name="SEC"/>
In 2000, Brem moved to [[George Washington University]] (GWU) where she became a Professor of Radiology at the George Washington University School of Medicine & Health Sciences.<ref name="GW"/><ref name="SEC"/>
In 2015 she became the Program Leader for Breast Cancer at the GW Cancer Center,<ref name="SPM"/> which is collaboratively operated by the GW Hospital, Medical Faculty Associates, School of Medicine and Health Sciences.<ref>{{cite web |title=We are the GW Cancer Center |url=https://cancercenter.gwu.edu/ |website=GW Cancer Center |access-date=5 May 2024}}</ref> She is currently the Director of Breast Imaging and Intervention at George Washington University Medical Center and a Professor of Radiology at George Washington University School of Medicine & Health Sciences, as well as a Vice Chair of Research and Faculty Development for the Department of Radiology.<ref name="Alliance"/><ref>{{Cite web |date=2015-10-07 |title=Director of Breast Imaging and Intervention |url=https://www.gwhospital.com/director-breast-imaging-and-intervention |access-date=2024-05-06 |website=George Washington University Hospital}}</ref>
In 2015 she became the Program Leader for Breast Cancer at the GW Cancer Center,<ref name="SPM"/> which is collaboratively operated by the GW Hospital, Medical Faculty Associates, School of Medicine and Health Sciences.<ref>{{cite web |title=We are the GW Cancer Center |url=https://cancercenter.gwu.edu/ |website=GW Cancer Center |access-date=May 5, 2024}}</ref> She is currently the Director of Breast Imaging and Intervention at George Washington University Medical Center and a Professor of Radiology at George Washington University School of Medicine & Health Sciences, as well as a Vice Chair of Research and Faculty Development for the Department of Radiology.<ref name="Alliance"/><ref>{{Cite web |date=October 7, 2015 |title=Director of Breast Imaging and Intervention |url=https://www.gwhospital.com/director-breast-imaging-and-intervention |access-date=May 6, 2024 |website=George Washington University Hospital}}</ref>


Brem is known for her research, publishing and mentoring of students.<ref name="JWI"/> Brem is a principal investigator for clinical trials which have included approaches to [[molecular breast imaging]] and detection of breast cancer. Brem is active in developing new technologies to decrease difficulty and cost and improve effectiveness of breast cancer diagnosis and treatment.<ref name="JWI"/><ref>{{Cite web |last= |first= |last2= |date=2012-12-15 |title=Molecular Breast Imaging an Option for Early Detection in High-risk Women |url=https://ascopost.com/issues/december-15-2012/molecular-breast-imaging-an-option-for-early-detection-in-high-risk-women/ |access-date=2024-05-06 |website=ascopost.com}}</ref> Approaches she is investigating include breast-specific gamma imaging (BSGI<ref>{{Cite journal |last1=De Feo |first1=Maria Silvia |last2=Sidrak |first2=Marko Magdi Abdou |last3=Conte |first3=Miriam |last4=Frantellizzi |first4=Viviana |last5=Marongiu |first5=Andrea |last6=De Cristofaro |first6=Flaminia |last7=Nuvoli |first7=Susanna |last8=Spanu |first8=Angela |last9=De Vincentis |first9=Giuseppe |date=2022-09-23 |title=Breast-Specific Gamma Imaging: An Added Value in the Diagnosis of Breast Cancer, a Systematic Review |journal=Cancers |volume=14 |issue=19 |pages=4619 |doi=10.3390/cancers14194619 |doi-access=free |issn=2072-6694 |pmc=9559460 |pmid=36230540}}</ref>), ultrasound tomography,<ref>{{cite news |title=Ultrasound Tomography May Improve Breast Cancer Risk Assessment |url=https://www.medimaging.net/ultrasound/articles/294781292/ultrasound-tomography-may-improve-breast-cancer-risk-assessment.html |work=MedImaging.net |date=25 March 2020}}</ref> the use of artificial intelligence to increase accuracy of cancer detection,<ref name="Moeller">{{cite news |last1=Moeller |first1=Amy |title=How Artificial Intelligence Is Improving Cancer Screening |url=https://www.washingtonian.com/2023/09/27/how-artificial-intelligence-is-improving-cancer-screening/ |work=Washingtonian |date=27 September 2023}}</ref> and the development of a non-invasive breath test for breast cancer detection.<ref name="Breathe"/><ref name="SPM"/><ref>{{cite web |title=Breast Cancer Diagnosis |url=https://www.gwhospital.com/services/breast-center/cancer-diagnosis |website=George Washington University Hospital |language=en-us |date=30 September 2015}}</ref>
Brem is known for her research, publishing and mentoring of students.<ref name="JWI"/> Brem is a principal investigator for clinical trials which have included approaches to [[molecular breast imaging]] and detection of breast cancer. Brem is active in developing new technologies to decrease difficulty and cost and improve effectiveness of breast cancer diagnosis and treatment.<ref name="JWI"/><ref>{{Cite web |last= |first= |last2= |date=December 15, 2012 |title=Molecular Breast Imaging an Option for Early Detection in High-risk Women |url=https://ascopost.com/issues/december-15-2012/molecular-breast-imaging-an-option-for-early-detection-in-high-risk-women/ |access-date=May 6, 2024 |website=ascopost.com}}</ref> Approaches she is investigating include breast-specific gamma imaging (BSGI<ref>{{Cite journal |last1=De Feo |first1=Maria Silvia |last2=Sidrak |first2=Marko Magdi Abdou |last3=Conte |first3=Miriam |last4=Frantellizzi |first4=Viviana |last5=Marongiu |first5=Andrea |last6=De Cristofaro |first6=Flaminia |last7=Nuvoli |first7=Susanna |last8=Spanu |first8=Angela |last9=De Vincentis |first9=Giuseppe |date=September 23, 2022 |title=Breast-Specific Gamma Imaging: An Added Value in the Diagnosis of Breast Cancer, a Systematic Review |journal=Cancers |volume=14 |issue=19 |pages=4619 |doi=10.3390/cancers14194619 |doi-access=free |issn=2072-6694 |pmc=9559460 |pmid=36230540}}</ref>), ultrasound tomography,<ref>{{cite news |title=Ultrasound Tomography May Improve Breast Cancer Risk Assessment |url=https://www.medimaging.net/ultrasound/articles/294781292/ultrasound-tomography-may-improve-breast-cancer-risk-assessment.html |work=MedImaging.net |date=March 25, 2020}}</ref> the use of artificial intelligence to increase accuracy of cancer detection,<ref name="Moeller">{{cite news |last1=Moeller |first1=Amy |title=How Artificial Intelligence Is Improving Cancer Screening |url=https://www.washingtonian.com/2023/09/27/how-artificial-intelligence-is-improving-cancer-screening/ |work=Washingtonian |date=September 27, 2023}}</ref> and the development of a non-invasive breath test for breast cancer detection.<ref name="Breathe"/><ref name="SPM"/><ref>{{cite web |title=Breast Cancer Diagnosis |url=https://www.gwhospital.com/services/breast-center/cancer-diagnosis |website=George Washington University Hospital |language=en-us |date=September 30, 2015}}</ref>


Brem has helped to develop two new breast imaging technologies which have been reviewed by the U.S. [[Food and Drug Administration]] (FDA) and approved for clinical use. In 2012, the FDA approved the Automated Breast Ultrasound System (ABUS).<ref name="ABUS">{{cite news |title=FDA Panel Recommends Approval for Automated Breast Ultrasound for Women with Dense Breasts |url=https://www.itnonline.com/content/fda-panel-recommends-approval-automated-breast-ultrasound-women-dense-breasts |work=Imaging Technology News |date=12 April 2012}}</ref><ref name="Bassett">{{cite news |last1=Bassett |first1=Mike |title=New technologies altering care standards for breast imagers |url=https://www.fiercehealthcare.com/it/new-technologies-altering-care-standards-for-breast-imagers |access-date=6 May 2024 |work=Fierce Healthcare |date=Apr 8, 2013}}</ref><ref>{{cite web |title=SUMMARY OF SAFETY AND EFFECTIVENESS DATA (SSED) |url=https://www.accessdata.fda.gov/cdrh_docs/pdf11/P110006b.pdf |website=PMA P110006: FDA Summary of Safety and Effectiveness Data}}</ref><ref name="Bene">{{cite journal |last1=Boca Bene |first1=I |last2=Ciurea |first2=AI |last3=Ciortea |first3=CA |last4=Dudea |first4=SM |title=Pros and Cons for Automated Breast Ultrasound (ABUS): A Narrative Review. |journal=Journal of Personalized Medicine |date=23 July 2021 |volume=11 |issue=8 |page=703 |doi=10.3390/jpm11080703 |doi-access=free |pmid=34442347 |pmc=8400952 }}</ref> In 2021, the FDA granted premarket approval (PMA) to the SoftVue™ 3D Whole Breast Ultrasound Tomography System as an adjunct to digital mammography.<ref name="Ernst">{{cite news |last1=Ernst |first1=Diana |title=FDA Approves Device to Screen Women With Dense Breasts as Adjunct to Mammography |url=https://www.empr.com/home/news/fda-approves-device-to-screen-women-with-dense-breasts-as-adjunct-to-mammography/ |access-date=6 May 2024 |work=Medical Professionals Reference |date=12 October 2021}}</ref><ref>{{Cite web |title=Delphinus Receives FDA Approval for its SoftVue 3D Whole Breast Ultrasound Tomography System |url=https://www.delphinusmt.com/news/recent-news/delphinus-receives-fda-approval-for-its-softvue-3d-whole-breast-ultrasound-tomography-system |access-date=2024-05-06 |website=www.delphinusmt.com}}</ref><ref>{{Cite web |title=Delphinus Medical Technologies, Inc. SoftVue™ 3D Whole Breast Ultrasound Tomography System (SoftVue™) |url=https://www.accessdata.fda.gov/cdrh_docs/pdf20/P200040C.pdf |website=FDA.gov}}</ref> Both are particularly suited to the detection of breast cancer in women with dense breasts.<ref name="ABUS"/><ref name="Ernst"/>
Brem has helped to develop two new breast imaging technologies which have been reviewed by the U.S. [[Food and Drug Administration]] (FDA) and approved for clinical use. In 2012, the FDA approved the Automated Breast Ultrasound System (ABUS).<ref name="ABUS">{{cite news |title=FDA Panel Recommends Approval for Automated Breast Ultrasound for Women with Dense Breasts |url=https://www.itnonline.com/content/fda-panel-recommends-approval-automated-breast-ultrasound-women-dense-breasts |work=Imaging Technology News |date=April 12, 2012}}</ref><ref name="Bassett">{{cite news |last1=Bassett |first1=Mike |title=New technologies altering care standards for breast imagers |url=https://www.fiercehealthcare.com/it/new-technologies-altering-care-standards-for-breast-imagers |access-date=May 6, 2024 |work=Fierce Healthcare |date=April 8, 2013}}</ref><ref>{{cite web |title=SUMMARY OF SAFETY AND EFFECTIVENESS DATA (SSED) |url=https://www.accessdata.fda.gov/cdrh_docs/pdf11/P110006b.pdf |website=PMA P110006: FDA Summary of Safety and Effectiveness Data}}</ref><ref name="Bene">{{cite journal |last1=Boca Bene |first1=I |last2=Ciurea |first2=AI |last3=Ciortea |first3=CA |last4=Dudea |first4=SM |title=Pros and Cons for Automated Breast Ultrasound (ABUS): A Narrative Review. |journal=Journal of Personalized Medicine |date=July 23, 2021 |volume=11 |issue=8 |page=703 |doi=10.3390/jpm11080703 |doi-access=free |pmid=34442347 |pmc=8400952 }}</ref> In 2021, the FDA granted premarket approval (PMA) to the SoftVue™ 3D Whole Breast Ultrasound Tomography System as an adjunct to digital mammography.<ref name="Ernst">{{cite news |last1=Ernst |first1=Diana |title=FDA Approves Device to Screen Women With Dense Breasts as Adjunct to Mammography |url=https://www.empr.com/home/news/fda-approves-device-to-screen-women-with-dense-breasts-as-adjunct-to-mammography/ |access-date=May 6, 2024 |work=Medical Professionals Reference |date=October 12, 2021}}</ref><ref>{{Cite web |title=Delphinus Receives FDA Approval for its SoftVue 3D Whole Breast Ultrasound Tomography System |url=https://www.delphinusmt.com/news/recent-news/delphinus-receives-fda-approval-for-its-softvue-3d-whole-breast-ultrasound-tomography-system |access-date=May 6, 2024 |website=www.delphinusmt.com}}</ref><ref>{{Cite web |title=Delphinus Medical Technologies, Inc. SoftVue™ 3D Whole Breast Ultrasound Tomography System (SoftVue™) |url=https://www.accessdata.fda.gov/cdrh_docs/pdf20/P200040C.pdf |website=FDA.gov}}</ref> Both are particularly suited to the detection of breast cancer in women with dense breasts.<ref name="ABUS"/><ref name="Ernst"/>


She has published over 100 journal articles about breast cancer.<ref>{{cite web |title=Rachel Brem - Publications Affiliations: Radiology The George Washington University, Washington, DC, United States |url=https://neurotree.org/neurotree/publications.php?pid=737607 |website=Neurotree}}</ref> She is the co-author with [[Christy Teal]] of the book ''No Longer Radical: Understanding Mastectomies and Choosing the Breast Cancer Care That's Right For You'' (2023).<ref name="Springen">{{cite journal |last1=Springen |first1=Karen |title=No Longer Radical: Understanding Mastectomies and Choosing the Breast Cancer Care That's Right for You |journal=Booklist |date=April 15, 2023 |volume=119 |issue=16}}</ref>
She has published over 100 journal articles about breast cancer.<ref>{{cite web |title=Rachel Brem - Publications Affiliations: Radiology The George Washington University, Washington, DC, United States |url=https://neurotree.org/neurotree/publications.php?pid=737607 |website=Neurotree}}</ref> She is the co-author with [[Christy Teal]] of the book ''No Longer Radical: Understanding Mastectomies and Choosing the Breast Cancer Care That's Right For You'' (2023).<ref name="Springen">{{cite journal |last1=Springen |first1=Karen |title=No Longer Radical: Understanding Mastectomies and Choosing the Breast Cancer Care That's Right for You |journal=Booklist |date=April 15, 2023 |volume=119 |issue=16}}</ref>


Brem has directed the Mobile Mammography program at George Washington University.<ref name="Alliance" /><ref name=":0" /><ref name=":1" /> The Mammovan initiative was organized in 1995,<ref name="Lynn">{{cite news |last1=Lynn |first1=Jean M. |last2=Segal |first2=Holly |date=2004 |title=A Model Breast Care Center at George Washington University Medical Center |url=https://www.accc-cancer.org/docs/documents/oncology-issues/supplements/breast-2004/a-model-breast-care-center-at-george-washington-university-medical-center.pdf?sfvrsn=cf3f79a4_0 |work=COMPREHENSIVE BREAST CARE PROGRAMS |issue=May/June}}</ref> before Brem joined GWU.<ref name="GW" /><ref name="SEC" /> By sending out mobile diagnostic units to neighborhoods and businesses, the project makes cancer care more accessible to women in underserved communities.<ref name="Alliance"/><ref name=":0">{{cite news |title=The GW Cancer Center Announces New Mobile Mammography Van in Washington, D.C. |url=https://cancercenter.gwu.edu/news/gw-cancer-center-announces-new-mobile-mammography-van-washington-dc |work=GW Cancer Center |date=17 October 2017}}</ref><ref name=":1">{{Cite web |title=Kiehl's Since 1851 Embarks On LifeRide For The Mammovan |url=https://engageforgood.com/kiehls-since-1851-embarks-on-liferide-for-the-mammovan/ |access-date=2024-05-05 |website=engageforgood.com}}</ref>
Brem has directed the Mobile Mammography program at George Washington University.<ref name="Alliance" /><ref name=":0" /><ref name=":1" /> The Mammovan initiative was organized in 1995,<ref name="Lynn">{{cite news |last1=Lynn |first1=Jean M. |last2=Segal |first2=Holly |date=2004 |title=A Model Breast Care Center at George Washington University Medical Center |url=https://www.accc-cancer.org/docs/documents/oncology-issues/supplements/breast-2004/a-model-breast-care-center-at-george-washington-university-medical-center.pdf?sfvrsn=cf3f79a4_0 |work=COMPREHENSIVE BREAST CARE PROGRAMS |issue=May/June}}</ref> before Brem joined GWU.<ref name="GW" /><ref name="SEC" /> By sending out mobile diagnostic units to neighborhoods and businesses, the project makes cancer care more accessible to women in underserved communities.<ref name="Alliance"/><ref name=":0">{{cite news |title=The GW Cancer Center Announces New Mobile Mammography Van in Washington, D.C. |url=https://cancercenter.gwu.edu/news/gw-cancer-center-announces-new-mobile-mammography-van-washington-dc |work=GW Cancer Center |date=October 17, 2017}}</ref><ref name=":1">{{Cite web |title=Kiehl's Since 1851 Embarks On LifeRide For The Mammovan |url=https://engageforgood.com/kiehls-since-1851-embarks-on-liferide-for-the-mammovan/ |access-date=May 5, 2024 |website=engageforgood.com}}</ref>


In 2004, Brem founded the Brem Foundation to Defeat Breast Cancer, to support research, education and clinical care.<ref name="Alliance" /><ref name="O'Malley">{{cite news |last1=O'Malley |first1=Lisa |title=Brem Foundation Improves Breast Cancer Outcomes for Underrepresented Women |url=https://www.insightintodiversity.com/brem-foundation-improves-breast-cancer-outcomes-for-underrepresented-women/ |work=Insight Into Diversity |date=2 January 2024}}</ref> Through the Brem Foundation, she has worked with [[Lyft]] to create the Lyft on Wheels for Women program, which provides free transportation to and from breast cancer screenings for women in the Washington, D.C., and Maryland areas. The Brem Foundation has also developed an online tool for risk assessment, called CheckMate, to help women assess their personal breast cancer risk given their family's medical history. They can then discuss the assessment and their concerns with their health care providers.<ref name="O'Malley" /><ref name="Amy">{{cite news |last1=Moeller |first1=Amy |title=This New Online Quiz Helps Women Determine Their Breast Cancer Risk - Washingtonian |url=https://www.washingtonian.com/2023/10/30/this-new-online-quiz-helps-women-determine-their-breast-cancer-risk/ |access-date=6 May 2024 |work=Washingtonian |date=30 October 2023}}</ref>
In 2004, Brem founded the Brem Foundation to Defeat Breast Cancer, to support research, education and clinical care.<ref name="Alliance" /><ref name="O'Malley">{{cite news |last1=O'Malley |first1=Lisa |title=Brem Foundation Improves Breast Cancer Outcomes for Underrepresented Women |url=https://www.insightintodiversity.com/brem-foundation-improves-breast-cancer-outcomes-for-underrepresented-women/ |work=Insight Into Diversity |date=January 2, 2024}}</ref> Through the Brem Foundation, she has worked with [[Lyft]] to create the Lyft on Wheels for Women program, which provides free transportation to and from breast cancer screenings for women in the Washington, D.C., and Maryland areas. The Brem Foundation has also developed an online tool for risk assessment, called CheckMate, to help women assess their personal breast cancer risk given their family's medical history. They can then discuss the assessment and their concerns with their health care providers.<ref name="O'Malley" /><ref name="Amy">{{cite news |last1=Moeller |first1=Amy |title=This New Online Quiz Helps Women Determine Their Breast Cancer Risk - Washingtonian |url=https://www.washingtonian.com/2023/10/30/this-new-online-quiz-helps-women-determine-their-breast-cancer-risk/ |access-date=May 6, 2024 |work=Washingtonian |date=October 30, 2023}}</ref>


Brem advises legislative policy-makers on the importance of education, awareness, diagnosis and treatment of breast cancer.<ref name="JWI"/> She advocates for policies to require that women with dense breasts be informed of the possible need for additional types of breast cancer screenings. She recommends that medical plans should cover breast cancer screening methods such as [[Magnetic resonance imaging|MRI]]s and ultrasounds, not just [[Mammography|mammograms]].<ref name="Ovalle">{{cite news |last1=Ovalle |first1=David |title=FDA sets national mammogram standards to protect women with dense breasts |url=https://www.washingtonpost.com/health/2023/03/09/mammogram-standards-dense-breasts/ |newspaper=Washington Post |date=9 March 2023}}</ref> She has supported legislation such as the bipartisan ''Find it Early Act''.<ref>{{Cite web |date=2023-05-08 |title=DeLauro, Fitzpatrick, Katie Couric Reintroduce the Find It Early Act {{!}} Congresswoman Rosa DeLauro |url=http://delauro.house.gov/media-center/press-releases/delauro-fitzpatrick-katie-couric-reintroduce-find-it-early-act |access-date=2024-05-06 |website=delauro.house.gov}}</ref>
Brem advises legislative policy-makers on the importance of education, awareness, diagnosis and treatment of breast cancer.<ref name="JWI"/> She advocates for policies to require that women with dense breasts be informed of the possible need for additional types of breast cancer screenings. She recommends that medical plans should cover breast cancer screening methods such as [[Magnetic resonance imaging|MRI]]s and ultrasounds, not just [[Mammography|mammograms]].<ref name="Ovalle">{{cite news |last1=Ovalle |first1=David |title=FDA sets national mammogram standards to protect women with dense breasts |url=https://www.washingtonpost.com/health/2023/03/09/mammogram-standards-dense-breasts/ |newspaper=Washington Post |date=March 9, 2023}}</ref> She has supported legislation such as the bipartisan ''Find it Early Act''.<ref>{{Cite web |date=May 8, 2023 |title=DeLauro, Fitzpatrick, Katie Couric Reintroduce the Find It Early Act {{!}} Congresswoman Rosa DeLauro |url=http://delauro.house.gov/media-center/press-releases/delauro-fitzpatrick-katie-couric-reintroduce-find-it-early-act |access-date=May 6, 2024 |website=delauro.house.gov}}</ref>


Brem serves on scientific advisory boards for the [[Prevent Cancer Foundation]],<ref>{{cite web |title=Medical Advisory Board |url=https://www.preventcancer.org/about-us/leadership-staff/medical-advisory-board/ |website=Prevent Cancer Foundation}}</ref> [[Facing Our Risk of Cancer Empowered]] (FORCE), and the [[Dr. Cyrus and Myrtle Katzen Cancer Research Center]].<ref name="Alliance"/> She was appointed to the Board of Delphinus Medical Technologies in 2019.<ref name="Delphinus">{{cite news |title=Delphinus Medical Technologies Appoints Dr. Rachel Brem to Its Board of Directors |url=https://www.businesswire.com/news/home/20190731005191/en/Delphinus-Medical-Technologies-Appoints-Dr.-Rachel-Brem-to-Its-Board-of-Directors |work=BusinessWire |date=31 July 2019}}</ref><ref>{{Cite web |title=Delphinus Medical Technologies Appoints Dr. Rachel Brem to Its Board of Directors |url=https://www.biospace.com/article/delphinus-medical-technologies-appoints-dr-rachel-brem-to-its-board-of-directors-/ |access-date=2024-05-06 |website=BioSpace |language=en-US}}</ref> As of 2024, she was appointed to the Board of Directors of Breathe BioMedical (BBM), serving as Executive Director and Chief Medical Officer.<ref name="Breathe"/>
Brem serves on scientific advisory boards for the [[Prevent Cancer Foundation]],<ref>{{cite web |title=Medical Advisory Board |url=https://www.preventcancer.org/about-us/leadership-staff/medical-advisory-board/ |website=Prevent Cancer Foundation}}</ref> [[Facing Our Risk of Cancer Empowered]] (FORCE), and the [[Dr. Cyrus and Myrtle Katzen Cancer Research Center]].<ref name="Alliance"/> She was appointed to the Board of Delphinus Medical Technologies in 2019.<ref name="Delphinus">{{cite news |title=Delphinus Medical Technologies Appoints Dr. Rachel Brem to Its Board of Directors |url=https://www.businesswire.com/news/home/20190731005191/en/Delphinus-Medical-Technologies-Appoints-Dr.-Rachel-Brem-to-Its-Board-of-Directors |work=BusinessWire |date=July 31, 2019}}</ref><ref>{{Cite web |title=Delphinus Medical Technologies Appoints Dr. Rachel Brem to Its Board of Directors |url=https://www.biospace.com/article/delphinus-medical-technologies-appoints-dr-rachel-brem-to-its-board-of-directors-/ |access-date=May 6, 2024 |website=BioSpace |language=en-US}}</ref> As of 2024, she was appointed to the Board of Directors of Breathe BioMedical (BBM), serving as Executive Director and Chief Medical Officer.<ref name="Breathe"/>


==Awards and honors==
==Awards and honors==
* 1998, Fellow, Society of Breast Imaging<ref name="Alliance"/><ref name="CV">{{cite web |title=Rachel F. Brem, M.D. 1 CURRICULUM VITAE ... - Brem Foundation |url=https://www.yumpu.com/en/document/read/9680843/rachel-f-brem-md-1-curriculum-vitae-brem-foundation |website=yumpu.com |access-date=12 May 2024}}</ref>
* 1998, Fellow, Society of Breast Imaging<ref name="Alliance"/><ref name="CV">{{cite web |title=Rachel F. Brem, M.D. 1 CURRICULUM VITAE ... - Brem Foundation |url=https://www.yumpu.com/en/document/read/9680843/rachel-f-brem-md-1-curriculum-vitae-brem-foundation |website=yumpu.com |access-date=May 12, 2024}}</ref>
* 2002, Ten Women to Watch, [[Jewish Women International]]<ref name="JWI">{{cite web |title=Previous Women to Watch |url=https://www.jwi.org/previous-women-to-watch |website=Jewish Women International |access-date=5 May 2024}}</ref>
* 2002, Ten Women to Watch, [[Jewish Women International]]<ref name="JWI">{{cite web |title=Previous Women to Watch |url=https://www.jwi.org/previous-women-to-watch |website=Jewish Women International |access-date=May 5, 2024}}</ref>
* 2009, Woman of Valor award, Chabad at Johns Hopkins<ref name="Chabad">{{cite web |title=Past Honorees - 2009 (5770) |url=https://www.chabadhopkins.org/templates/articlecco_cdo/aid/1012154/jewish/Past-Honorees-2009-5770.htm |website=Chabad at Johns Hopkins}}</ref>
* 2009, Woman of Valor award, Chabad at Johns Hopkins<ref name="Chabad">{{cite web |title=Past Honorees - 2009 (5770) |url=https://www.chabadhopkins.org/templates/articlecco_cdo/aid/1012154/jewish/Past-Honorees-2009-5770.htm |website=Chabad at Johns Hopkins}}</ref>
* 2010, Editors Recognition Awards, with distinction, ''[[Radiology (journal)|Radiology]]''<ref name="Kressel">{{cite journal |last1=Kressel |first1=Herbert Y. |title=Editor's Recognition Awards |journal=Radiology |date=January 2011 |volume=258 |issue=1 |pages=10–11 |doi=10.1148/radiol.10102022 |url=https://doi.org/10.1148/radiol.10102022 |language=en |issn=0033-8419}}</ref>
* 2010, Editors Recognition Awards, with distinction, ''[[Radiology (journal)|Radiology]]''<ref name="Kressel">{{cite journal |last1=Kressel |first1=Herbert Y. |title=Editor's Recognition Awards |journal=Radiology |date=January 2011 |volume=258 |issue=1 |pages=10–11 |doi=10.1148/radiol.10102022 |url=https://doi.org/10.1148/radiol.10102022 |language=en |issn=0033-8419}}</ref>
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==Selected publications==
==Selected publications==
* {{cite book |last1=Brem |first1=Rachel |last2=Teal |first2=Christy |title=No Longer Radical: Understanding Mastectomies and Choosing the Breast Cancer Care That's Right For You |date=16 May 2023 |publisher=Simon and Schuster |isbn=978-1-6680-0115-8 |url=https://books.google.com/books?id=7UyUEAAAQBAJ&q=Newsweek:+2015+rachel+brem}}
* {{cite book |last1=Brem |first1=Rachel |last2=Teal |first2=Christy |title=No Longer Radical: Understanding Mastectomies and Choosing the Breast Cancer Care That's Right For You |date=May 16, 2023 |publisher=Simon and Schuster |isbn=978-1-6680-0115-8 |url=https://books.google.com/books?id=7UyUEAAAQBAJ&q=Newsweek:+2015+rachel+brem}}
* {{cite journal |last1=Zafar |first1=Nadia |last2=Wolf |first2=Andrea B |last3=Kepniss |first3=Julia L |last4=Teal |first4=Ashley C |last5=Brem |first5=Rachel F |title=Effectiveness of Community Education for Breast Cancer Screening |journal=Journal of Breast Imaging |date=1 April 2024 |volume=6 |issue=2 |pages=166–174 |doi=10.1093/jbi/wbae002|pmid=38412358 }}
* {{cite journal |last1=Zafar |first1=Nadia |last2=Wolf |first2=Andrea B |last3=Kepniss |first3=Julia L |last4=Teal |first4=Ashley C |last5=Brem |first5=Rachel F |title=Effectiveness of Community Education for Breast Cancer Screening |journal=Journal of Breast Imaging |date=April 1, 2024 |volume=6 |issue=2 |pages=166–174 |doi=10.1093/jbi/wbae002|pmid=38412358 }}
* {{cite journal |last1=Katzen |first1=Janine T |last2=Grimm |first2=Lars J |last3=Brem |first3=Rachel F |title=The American College of Radiology/Society of Breast Imaging Updated Fellowship Training Curriculum for Breast Imaging |journal=Journal of Breast Imaging |date=7 January 2021 |volume=3 |issue=4 |pages=498–501 |doi=10.1093/jbi/wbaa112 |pmid=38424786 |url=https://doi.org/10.1093/jbi/wbaa112 |issn=2631-6110}}
* {{cite journal |last1=Katzen |first1=Janine T |last2=Grimm |first2=Lars J |last3=Brem |first3=Rachel F |title=The American College of Radiology/Society of Breast Imaging Updated Fellowship Training Curriculum for Breast Imaging |journal=Journal of Breast Imaging |date=January 7, 2021 |volume=3 |issue=4 |pages=498–501 |doi=10.1093/jbi/wbaa112 |pmid=38424786 |url=https://doi.org/10.1093/jbi/wbaa112 |issn=2631-6110}}
* {{cite journal |last1=Duric |first1=Neb |last2=Sak |first2=Mark |last3=Fan |first3=Shaoqi |last4=Pfeiffer |first4=Ruth M. |last5=Littrup |first5=Peter J. |last6=Simon |first6=Michael S. |last7=Gorski |first7=David H. |last8=Ali |first8=Haythem |last9=Purrington |first9=Kristen S. |last10=Brem |first10=Rachel F. |last11=Sherman |first11=Mark E. |last12=Gierach |first12=Gretchen L. |title=Using Whole Breast Ultrasound Tomography to Improve Breast Cancer Risk Assessment: A Novel Risk Factor Based on the Quantitative Tissue Property of Sound Speed |journal=Journal of Clinical Medicine |date=February 2020 |volume=9 |issue=2 |pages=367 |doi=10.3390/jcm9020367 |doi-access=free |pmid=32013177 |language=en |issn=2077-0383|pmc=7074100 }}
* {{cite journal |last1=Duric |first1=Neb |last2=Sak |first2=Mark |last3=Fan |first3=Shaoqi |last4=Pfeiffer |first4=Ruth M. |last5=Littrup |first5=Peter J. |last6=Simon |first6=Michael S. |last7=Gorski |first7=David H. |last8=Ali |first8=Haythem |last9=Purrington |first9=Kristen S. |last10=Brem |first10=Rachel F. |last11=Sherman |first11=Mark E. |last12=Gierach |first12=Gretchen L. |title=Using Whole Breast Ultrasound Tomography to Improve Breast Cancer Risk Assessment: A Novel Risk Factor Based on the Quantitative Tissue Property of Sound Speed |journal=Journal of Clinical Medicine |date=February 2020 |volume=9 |issue=2 |pages=367 |doi=10.3390/jcm9020367 |doi-access=free |pmid=32013177 |language=en |issn=2077-0383|pmc=7074100 }}
* {{cite journal |last1=Huppe |first1=Ashley I. |last2=Mehta |first2=Anita K. |last3=Brem |first3=Rachel F. |title=Molecular Breast Imaging: A Comprehensive Review |journal=Seminars in Ultrasound, CT, and MR |date=February 2018 |volume=39 |issue=1 |pages=60–69 |doi=10.1053/j.sult.2017.10.001 |pmid=29317040 |url=https://pubmed.ncbi.nlm.nih.gov/29317040/ |issn=1558-5034}}
* {{cite journal |last1=Huppe |first1=Ashley I. |last2=Mehta |first2=Anita K. |last3=Brem |first3=Rachel F. |title=Molecular Breast Imaging: A Comprehensive Review |journal=Seminars in Ultrasound, CT, and MR |date=February 2018 |volume=39 |issue=1 |pages=60–69 |doi=10.1053/j.sult.2017.10.001 |pmid=29317040 |url=https://pubmed.ncbi.nlm.nih.gov/29317040/ |issn=1558-5034}}
* {{cite journal |last1=Thigpen |first1=Denise |last2=Kappler |first2=Amanda |last3=Brem |first3=Rachel |title=The Role of Ultrasound in Screening Dense Breasts—A Review of the Literature and Practical Solutions for Implementation |journal=Diagnostics |date=16 March 2018 |volume=8 |issue=1 |pages=20 |doi=10.3390/diagnostics8010020 |doi-access=free |pmid=29547532 |pmc=5872003 }}
* {{cite journal |last1=Thigpen |first1=Denise |last2=Kappler |first2=Amanda |last3=Brem |first3=Rachel |title=The Role of Ultrasound in Screening Dense Breasts—A Review of the Literature and Practical Solutions for Implementation |journal=Diagnostics |date=March 16, 2018 |volume=8 |issue=1 |pages=20 |doi=10.3390/diagnostics8010020 |doi-access=free |pmid=29547532 |pmc=5872003 }}
* {{cite journal |last1=Brem |first1=Rachel F. |last2=Tabár |first2=László |last3=Duffy |first3=Stephen W. |last4=Inciardi |first4=Marc F. |last5=Guingrich |first5=Jessica A. |last6=Hashimoto |first6=Beverly E. |last7=Lander |first7=Marla R. |last8=Lapidus |first8=Robert L. |last9=Peterson |first9=Mary Kay |last10=Rapelyea |first10=Jocelyn A. |last11=Roux |first11=Susan |last12=Schilling |first12=Kathy J. |last13=Shah |first13=Biren A. |last14=Torrente |first14=Jessica |last15=Wynn |first15=Ralph T. |last16=Miller |first16=Dave P. |title=Assessing Improvement in Detection of Breast Cancer with Three-dimensional Automated Breast US in Women with Dense Breast Tissue: The SomoInsight Study |journal=Radiology |date=March 2015 |volume=274 |issue=3 |pages=663–673 |doi=10.1148/radiol.14132832 |pmid=25329763 |url=https://doi.org/10.1148/radiol.14132832 |language=en |issn=0033-8419}}
* {{cite journal |last1=Brem |first1=Rachel F. |last2=Tabár |first2=László |last3=Duffy |first3=Stephen W. |last4=Inciardi |first4=Marc F. |last5=Guingrich |first5=Jessica A. |last6=Hashimoto |first6=Beverly E. |last7=Lander |first7=Marla R. |last8=Lapidus |first8=Robert L. |last9=Peterson |first9=Mary Kay |last10=Rapelyea |first10=Jocelyn A. |last11=Roux |first11=Susan |last12=Schilling |first12=Kathy J. |last13=Shah |first13=Biren A. |last14=Torrente |first14=Jessica |last15=Wynn |first15=Ralph T. |last16=Miller |first16=Dave P. |title=Assessing Improvement in Detection of Breast Cancer with Three-dimensional Automated Breast US in Women with Dense Breast Tissue: The SomoInsight Study |journal=Radiology |date=March 2015 |volume=274 |issue=3 |pages=663–673 |doi=10.1148/radiol.14132832 |pmid=25329763 |url=https://doi.org/10.1148/radiol.14132832 |language=en |issn=0033-8419}}
* {{cite journal |last1=Rechtman |first1=Lauren R. |last2=Lenihan |first2=Megan J. |last3=Lieberman |first3=Jennifer H. |last4=Teal |first4=Christine B. |last5=Torrente |first5=Jessica |last6=Rapelyea |first6=Jocelyn A. |last7=Brem |first7=Rachel F. |title=Breast-Specific Gamma Imaging for the Detection of Breast Cancer in Dense Versus Nondense Breasts |journal=American Journal of Roentgenology |date=February 2014 |volume=202 |issue=2 |pages=293–298 |doi=10.2214/AJR.13.11585 |pmid=24450668 |url=https://doi.org/10.2214/AJR.13.11585 |language=en |issn=0361-803X}}
* {{cite journal |last1=Rechtman |first1=Lauren R. |last2=Lenihan |first2=Megan J. |last3=Lieberman |first3=Jennifer H. |last4=Teal |first4=Christine B. |last5=Torrente |first5=Jessica |last6=Rapelyea |first6=Jocelyn A. |last7=Brem |first7=Rachel F. |title=Breast-Specific Gamma Imaging for the Detection of Breast Cancer in Dense Versus Nondense Breasts |journal=American Journal of Roentgenology |date=February 2014 |volume=202 |issue=2 |pages=293–298 |doi=10.2214/AJR.13.11585 |pmid=24450668 |url=https://doi.org/10.2214/AJR.13.11585 |language=en |issn=0361-803X}}

Revision as of 19:16, 12 June 2024

Rachel Brem
Alma mater
OccupationRadiologist Edit this on Wikidata
Employer
Spouse(s)Henry Brem Edit this on Wikidata
Awards
  • Fellow of the American College of Radiology (2011) Edit this on Wikidata

Rachel F. Brem, MD, FACR, FSBI, is an American diagnostic radiologist, professor of radiology at the George Washington University School of Medicine & Health Sciences, and director of the Breast Imaging and Interventional Center at George Washington University’s Cancer Center. She previously served as director of Breast Imaging at Johns Hopkins.[1][2] Brem develops novel technologies to better support early diagnosis and treatment of breast cancer.[3] She is a fellow of the American College of Radiology and the Society of Breast Imaging.[4]

Early life and education

Rachel Frydman was born to Mechel Frydman and Lea Fishman, of Glen Rock, New Jersey.[5][6] From a young age, Rachel wanted to be a doctor, a decision that was reinforced when her mother, Lea Frydman, was diagnosed with breast cancer when Brem was 12 years old. Despite being given only six months to live, Lea went on to survive breast and ovarian cancer and live for another 44 years.[7]

Rachel became engaged to Henry Brem, then a medical student, while she was a student at Brandeis.[5] Rachel Brem received a B.A. from Brandeis University in 1979. She then went to Columbia University's medical school, graduating with honors in 1984.[8][4] Brem completed an internship in internal medicine at Sinai Hospital of Baltimore[9] (1984–1985[10]), and a residency in diagnostic radiology (1985–1989) and a fellowship in breast imaging (1989–1990) at Johns Hopkins. She holds board certification in diagnostic radiology.[11]

In the mid-1990s, researchers discovered that Ashkenazi Jewish families were at higher risk for breast cancer due to the BRCA mutation. In 1996, after a maternal aunt had also been diagnosed with breast cancer, Brem chose to be tested for the gene. It was detected, and she scheduled a radical mastectomy on the basis of her genetic results. Ironically, she subsequently detected the presence of an existing tumor in her breast while testing ultrasound equipment for her hospital.[7][12] Brem strongly recommends early testing for women who are of Ashkenazi Jewish descent or who have a family history of breast cancer.[7]

Career

External videos
video icon Co-Pilot Your Breast Health with Dr. Rachel Brem, March 19, 2024
video icon Dr. Rachel Brem is a Breast Cancer Survivor and now a COVID-19 Survivor and she has an Important Message to Share with You, April 3, 2020

After completing her training, Brem joined the faculty at Johns Hopkins, where she became the Director of Breast Imaging.[2] Between 1991 and 1999 she introduced the use of image-guided techniques for minimally invasive surgery at Johns Hopkins.[13] Throughout her career she has been active in developing new technologies for early, less invasive detection of breast cancer[14][15] particularly in women with dense breast tissue.[2][16]

In 2000, Brem moved to George Washington University (GWU) where she became a Professor of Radiology at the George Washington University School of Medicine & Health Sciences.[1][13] In 2015 she became the Program Leader for Breast Cancer at the GW Cancer Center,[2] which is collaboratively operated by the GW Hospital, Medical Faculty Associates, School of Medicine and Health Sciences.[17] She is currently the Director of Breast Imaging and Intervention at George Washington University Medical Center and a Professor of Radiology at George Washington University School of Medicine & Health Sciences, as well as a Vice Chair of Research and Faculty Development for the Department of Radiology.[4][18]

Brem is known for her research, publishing and mentoring of students.[19] Brem is a principal investigator for clinical trials which have included approaches to molecular breast imaging and detection of breast cancer. Brem is active in developing new technologies to decrease difficulty and cost and improve effectiveness of breast cancer diagnosis and treatment.[19][20] Approaches she is investigating include breast-specific gamma imaging (BSGI[21]), ultrasound tomography,[22] the use of artificial intelligence to increase accuracy of cancer detection,[16] and the development of a non-invasive breath test for breast cancer detection.[9][2][23]

Brem has helped to develop two new breast imaging technologies which have been reviewed by the U.S. Food and Drug Administration (FDA) and approved for clinical use. In 2012, the FDA approved the Automated Breast Ultrasound System (ABUS).[24][25][26][27] In 2021, the FDA granted premarket approval (PMA) to the SoftVue™ 3D Whole Breast Ultrasound Tomography System as an adjunct to digital mammography.[28][29][30] Both are particularly suited to the detection of breast cancer in women with dense breasts.[24][28]

She has published over 100 journal articles about breast cancer.[31] She is the co-author with Christy Teal of the book No Longer Radical: Understanding Mastectomies and Choosing the Breast Cancer Care That's Right For You (2023).[32]

Brem has directed the Mobile Mammography program at George Washington University.[4][33][34] The Mammovan initiative was organized in 1995,[35] before Brem joined GWU.[1][13] By sending out mobile diagnostic units to neighborhoods and businesses, the project makes cancer care more accessible to women in underserved communities.[4][33][34]

In 2004, Brem founded the Brem Foundation to Defeat Breast Cancer, to support research, education and clinical care.[4][36] Through the Brem Foundation, she has worked with Lyft to create the Lyft on Wheels for Women program, which provides free transportation to and from breast cancer screenings for women in the Washington, D.C., and Maryland areas. The Brem Foundation has also developed an online tool for risk assessment, called CheckMate, to help women assess their personal breast cancer risk given their family's medical history. They can then discuss the assessment and their concerns with their health care providers.[36][37]

Brem advises legislative policy-makers on the importance of education, awareness, diagnosis and treatment of breast cancer.[19] She advocates for policies to require that women with dense breasts be informed of the possible need for additional types of breast cancer screenings. She recommends that medical plans should cover breast cancer screening methods such as MRIs and ultrasounds, not just mammograms.[38] She has supported legislation such as the bipartisan Find it Early Act.[39]

Brem serves on scientific advisory boards for the Prevent Cancer Foundation,[40] Facing Our Risk of Cancer Empowered (FORCE), and the Dr. Cyrus and Myrtle Katzen Cancer Research Center.[4] She was appointed to the Board of Delphinus Medical Technologies in 2019.[41][42] As of 2024, she was appointed to the Board of Directors of Breathe BioMedical (BBM), serving as Executive Director and Chief Medical Officer.[9]

Awards and honors

Selected publications

References

  1. ^ a b c "Rachel Brem, MD". GW Medical Faculty Associates. Retrieved May 5, 2024.
  2. ^ a b c d e "Dr Rachel Brem". Screen Point Medical. Retrieved May 5, 2024.
  3. ^ a b "Past Honorees - 2009 (5770)". Chabad at Johns Hopkins.
  4. ^ a b c d e f g h "We are proud to welcome two new members of our medical advisory board: Dr. Rachel Brem and Dr. Eleni Tousimis". Outlook. Vol. 24, no. 2. Breast Cancer Alliance. 2018. p. 4. Retrieved May 5, 2024.
  5. ^ a b "Henry Brem Fiance Of Rachel Frydman". The New York Times. March 20, 1977.
  6. ^ "Mechel Frydman Obituary (2015) - Pikesville, MD - Concord Monitor". Legacy.com. Retrieved May 6, 2024.
  7. ^ a b c Bergel, Tori (June 7, 2023). "The Washington doctors helping women navigate breast cancer". Jewish Insider. Retrieved May 5, 2024. In a twist of fate, Brem discovered her own breast cancer while testing new ultrasound equipment at the hospital.
  8. ^ "Rachel Brem, MD". GW Cancer Center.
  9. ^ a b c "Breathe BioMedical announces new Executive Director". Canadian Manufacturing. January 9, 2024. Retrieved May 5, 2024.
  10. ^ "Dr. Rachel F. Brem MD". US News Health.
  11. ^ a b c d "Dr. Rachel F. Brem - Diagnostic Radiology - Washington, DC". Castle Connolly. Retrieved May 5, 2024.
  12. ^ Brem, Rachel; Teal, Christy (May 16, 2023). No Longer Radical: Understanding Mastectomies and Choosing the Breast Cancer Care That's Right For You. Simon and Schuster. ISBN 978-1-6680-0115-8.
  13. ^ a b c "Definitive Proxy Statement". www.sec.gov.
  14. ^ Radiological Society of North America (December 9, 2008). "New Breast Imaging Technology Targets Hard-to-detect Cancers". ScienceDaily.
  15. ^ Orenstein, Beth W. (2023). "A better option: New technology improves the utility of breast ultrasound". Radiology Today. No. January. pp. 19–21.
  16. ^ a b Moeller, Amy (September 27, 2023). "How Artificial Intelligence Is Improving Cancer Screening". Washingtonian.
  17. ^ "We are the GW Cancer Center". GW Cancer Center. Retrieved May 5, 2024.
  18. ^ "Director of Breast Imaging and Intervention". George Washington University Hospital. October 7, 2015. Retrieved May 6, 2024.
  19. ^ a b c d "Previous Women to Watch". Jewish Women International. Retrieved May 5, 2024.
  20. ^ "Molecular Breast Imaging an Option for Early Detection in High-risk Women". ascopost.com. December 15, 2012. Retrieved May 6, 2024.
  21. ^ De Feo, Maria Silvia; Sidrak, Marko Magdi Abdou; Conte, Miriam; Frantellizzi, Viviana; Marongiu, Andrea; De Cristofaro, Flaminia; Nuvoli, Susanna; Spanu, Angela; De Vincentis, Giuseppe (September 23, 2022). "Breast-Specific Gamma Imaging: An Added Value in the Diagnosis of Breast Cancer, a Systematic Review". Cancers. 14 (19): 4619. doi:10.3390/cancers14194619. ISSN 2072-6694. PMC 9559460. PMID 36230540.
  22. ^ "Ultrasound Tomography May Improve Breast Cancer Risk Assessment". MedImaging.net. March 25, 2020.
  23. ^ "Breast Cancer Diagnosis". George Washington University Hospital. September 30, 2015.
  24. ^ a b "FDA Panel Recommends Approval for Automated Breast Ultrasound for Women with Dense Breasts". Imaging Technology News. April 12, 2012.
  25. ^ Bassett, Mike (April 8, 2013). "New technologies altering care standards for breast imagers". Fierce Healthcare. Retrieved May 6, 2024.
  26. ^ "SUMMARY OF SAFETY AND EFFECTIVENESS DATA (SSED)" (PDF). PMA P110006: FDA Summary of Safety and Effectiveness Data.
  27. ^ Boca Bene, I; Ciurea, AI; Ciortea, CA; Dudea, SM (July 23, 2021). "Pros and Cons for Automated Breast Ultrasound (ABUS): A Narrative Review". Journal of Personalized Medicine. 11 (8): 703. doi:10.3390/jpm11080703. PMC 8400952. PMID 34442347.
  28. ^ a b Ernst, Diana (October 12, 2021). "FDA Approves Device to Screen Women With Dense Breasts as Adjunct to Mammography". Medical Professionals Reference. Retrieved May 6, 2024.
  29. ^ "Delphinus Receives FDA Approval for its SoftVue 3D Whole Breast Ultrasound Tomography System". www.delphinusmt.com. Retrieved May 6, 2024.
  30. ^ "Delphinus Medical Technologies, Inc. SoftVue™ 3D Whole Breast Ultrasound Tomography System (SoftVue™)" (PDF). FDA.gov.
  31. ^ "Rachel Brem - Publications Affiliations: Radiology The George Washington University, Washington, DC, United States". Neurotree.
  32. ^ Springen, Karen (April 15, 2023). "No Longer Radical: Understanding Mastectomies and Choosing the Breast Cancer Care That's Right for You". Booklist. 119 (16).
  33. ^ a b "The GW Cancer Center Announces New Mobile Mammography Van in Washington, D.C." GW Cancer Center. October 17, 2017.
  34. ^ a b "Kiehl's Since 1851 Embarks On LifeRide For The Mammovan". engageforgood.com. Retrieved May 5, 2024.
  35. ^ Lynn, Jean M.; Segal, Holly (2004). "A Model Breast Care Center at George Washington University Medical Center" (PDF). COMPREHENSIVE BREAST CARE PROGRAMS. No. May/June.
  36. ^ a b O'Malley, Lisa (January 2, 2024). "Brem Foundation Improves Breast Cancer Outcomes for Underrepresented Women". Insight Into Diversity.
  37. ^ Moeller, Amy (October 30, 2023). "This New Online Quiz Helps Women Determine Their Breast Cancer Risk - Washingtonian". Washingtonian. Retrieved May 6, 2024.
  38. ^ Ovalle, David (March 9, 2023). "FDA sets national mammogram standards to protect women with dense breasts". Washington Post.
  39. ^ "DeLauro, Fitzpatrick, Katie Couric Reintroduce the Find It Early Act | Congresswoman Rosa DeLauro". delauro.house.gov. May 8, 2023. Retrieved May 6, 2024.
  40. ^ "Medical Advisory Board". Prevent Cancer Foundation.
  41. ^ "Delphinus Medical Technologies Appoints Dr. Rachel Brem to Its Board of Directors". BusinessWire. July 31, 2019.
  42. ^ "Delphinus Medical Technologies Appoints Dr. Rachel Brem to Its Board of Directors". BioSpace. Retrieved May 6, 2024.
  43. ^ "Rachel F. Brem, M.D. 1 CURRICULUM VITAE ... - Brem Foundation". yumpu.com. Retrieved May 12, 2024.
  44. ^ Kressel, Herbert Y. (January 2011). "Editor's Recognition Awards". Radiology. 258 (1): 10–11. doi:10.1148/radiol.10102022. ISSN 0033-8419.
  45. ^ "SMHS Physician Inducted as a Fellow in the American College of Radiology". School of Medicine and Health Sciences. May 21, 2011.
  46. ^ "ACR Fellows List" (PDF). ACR. 2024.
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