Icodextrin: Difference between revisions
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Anypodetos (talk | contribs) CAS, DrugBank, KEGG, additional trade name and ref |
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| image = |
| image = |
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| synonyms = |
| synonyms = |
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| CAS_number = |
| CAS_number = 337376-15-5 |
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| CAS_supplemental = |
| CAS_supplemental = |
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| ATC_prefix = B05 |
| ATC_prefix = B05 |
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| ATC_suffix = DA |
| ATC_suffix = DA |
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| ATC_supplemental = |
| ATC_supplemental = |
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| PubChemSubstance = 17397419 |
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| PubChem = |
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| DrugBank = |
| DrugBank = DB00702 |
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| KEGG = |
| KEGG = D03266 |
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| chemical_formula = |
| chemical_formula = |
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| molecular_weight = 13–19 [[kDa]] |
| molecular_weight = 13–19 [[kDa]] |
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'''Icodextrin''' is a [[colloid]] [[osmotic]] agent used for [[peritoneal dialysis]] in form of a solution under the trade |
'''Icodextrin''' ([[International Nonproprietary Name|INN]], [[United States Adopted Name|USAN]]) is a [[colloid]] [[osmotic]] agent used for [[peritoneal dialysis]] in form of a solution under the trade names '''Adept''' and '''Extraneal'''. Icodextrin is a starch-derived, water-soluble glucose polymer linked by alpha (1-4) and less than 10% alpha (1-6) [[glycosidic bond]]s with a weight-average molecular weight between 13,000 and 19,000 [[Dalton (unit)|Dalton]]s and a number-average molecular weight between 5,000 and 6,500 Daltons. |
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==References== |
==References== |
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* FDA: [http://www.accessdata.fda.gov/cdrh_docs/pdf5/P050011c.pdf Adept® (4% Icodextrin) Adhesion Reduction Solution] |
* FDA: [http://www.accessdata.fda.gov/cdrh_docs/pdf5/P050011c.pdf Adept® (4% Icodextrin) Adhesion Reduction Solution] |
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* {{pmid|12962523}} |
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{{B03, B05, B06}} |
{{B03, B05, B06}} |
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Revision as of 12:13, 10 March 2011
| Clinical data | |
|---|---|
| Routes of administration | Intraperitoneal |
| ATC code | |
| Legal status | |
| Legal status |
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| Pharmacokinetic data | |
| Bioavailability | 40% in 12 hours |
| Metabolism | alpha-amylase |
| Excretion | Renal |
| Identifiers | |
| CAS Number | |
| PubChem SID | |
| DrugBank | |
| KEGG | |
| CompTox Dashboard (EPA) | |
| Chemical and physical data | |
| Molar mass | 13–19 kDa |
Icodextrin (INN, USAN) is a colloid osmotic agent used for peritoneal dialysis in form of a solution under the trade names Adept and Extraneal. Icodextrin is a starch-derived, water-soluble glucose polymer linked by alpha (1-4) and less than 10% alpha (1-6) glycosidic bonds with a weight-average molecular weight between 13,000 and 19,000 Daltons and a number-average molecular weight between 5,000 and 6,500 Daltons.
References
 | This drug article relating to the blood and blood forming organs is a stub. You can help Wikipedia by expanding it. |