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'''Seattle BioMed''', known prior to 2010 as '''Seattle Biomedical Research Institute''' or '''SBRI''', is the largest independent, non-profit organization in the United States focused solely on [[infectious disease]] discovery research.<ref>http://seattlebusinessmag.com/blog/seattle-biomed-announces-major-scientific-expansion/</ref> The mission of Seattle BioMed's 360+ employees is to eliminate the world's most devastating infectious diseases through leadership in scientific discovery. Seattle BioMed is headquartered and has research labs in the South Lake Union area of [[Seattle, WA]] and has field labs in Tanzania. Seattle BioMed's research focuses on four areas of infectious disease: [[HIV/AIDS]], [[malaria]], [[tuberculosis|tuberculosos (TB)]], and Emerging & Neglected Diseases (END) like [[African sleeping sickness|African trypanosomiasis]], [[leishmaniasis]], [[Chagas disease]], and [[toxoplasmosis]]. Seattle BioMed is engaged in early stages of the scientific pipeline including bench science and [[clinical trials|clinical trials]] and has expertise in [[immunology]], vaccinology, and drug discovery.
'''Seattle BioMed''', known prior to 2010 as '''Seattle Biomedical Research Institute''' or '''SBRI''', is the largest independent, non-profit organization in the United States focused solely on [[infectious disease]] discovery research. The mission of Seattle BioMed's 360+ employees is to eliminate the world's most devastating infectious diseases through leadership in scientific discovery. Seattle BioMed is headquartered and has research labs in the South Lake Union area of [[Seattle, WA]] and has field labs in Tanzania. Seattle BioMed's research focuses on four areas of infectious disease: [[HIV/AIDS]], [[malaria]], [[tuberculosis|tuberculosos (TB)]], and Emerging & Neglected Diseases (END) like [[African sleeping sickness|African trypanosomiasis]], [[leishmaniasis]], [[Chagas disease]], and [[toxoplasmosis]]. Seattle BioMed is engaged in early stages of the scientific pipeline including bench science and [[clinical trials|clinical trials]] and has expertise in [[immunology]], vaccinology, and drug discovery.



==History==
==History==
[[Image:Seattle Biomed.jpg|thumb|right|Seattle BioMed headquarters on Westlake Avenue]]
[[Image:Seattle Biomed.jpg|thumb|right|Seattle BioMed headquarters on Westlake Avenue]]
In 1976, founders Ruth W. Shearer, Ph.D., and [[Ken Stuart|Kenneth Stuart, Ph.D.]], set up a research laboratory in [[Issaquah, WA]].<ref>http://seattletimes.com/html/thebusinessofgiving/2011453366_seattle_biomed_moves_from_to_r.html/</ref> Originally called the Issaquah Group for Health and Environmental Research, the name was soon changed to Issaquah Biomedical Research Institute. Scientists at the Institute studied parasites including ones that cause malaria and African sleeping sickness. In 1986, the Institute relocated to [[Seattle, Washington]] to enhance its scientific programs and became Seattle Biomedical Research Institute.<ref>http://humanosphere.kplu.org/2011/06/working-class-kid-builds-a-world-class-research-institute-in-seattle-after-starting-in-a-strip-mall/</ref>
In 1976, founders Ruth W. Shearer, Ph.D., and [[Ken Stuart|Kenneth Stuart, Ph.D.]], set up a research laboratory in [[Issaquah, WA]]. Originally called the Issaquah Group for Health and Environmental Research, the name was soon changed to Issaquah Biomedical Research Institute. Scientists at the Institute studied parasites including ones that cause malaria and African sleeping sickness. In 1986, the Institute relocated to [[Seattle, Washington]] to enhance its scientific programs and became Seattle Biomedical Research Institute.<ref>http://humanosphere.kplu.org/2011/06/working-class-kid-builds-a-world-class-research-institute-in-seattle-after-starting-in-a-strip-mall/</ref>


In January 2012, [[Alan Aderem|Alan Aderem, Ph.D.]] became president of Seattle BioMed, only the second in its 36 year history, with Dr. Stuart remaining in an active role as President Emeritus and Founder. As part of the Institute's plan for scientific expansion, Dr. Aderem is leading the implementation of integrating [[systems biology]] approaches to understanding infectious disease.<ref>http://www.genomeweb.com/alan-aderem-joins-ken-stuarts-seattle-biomedical-research-institute/</ref>
In January 2012, [[Alan Aderem|Alan Aderem, Ph.D.]] became president of Seattle BioMed, only the second in its 36 year history, with Dr. Stuart remaining in an active role as President Emeritus and Founder. As part of the Institute's plan for scientific expansion, Dr. Aderem is leading the implementation of integrating [[systems biology]] approaches to understanding infectious disease.<ref>http://www.genomeweb.com/alan-aderem-joins-ken-stuarts-seattle-biomedical-research-institute/</ref>


==Current Research==
Seattle BioMed performs research on four areas of infectious disease:[[HIV/AIDS]], [[malaria]], [[tuberculosis|tuberculosis (TB)]], and Emerging & Neglected Diseases (END) like [[African sleeping sickness|African trypanosomiasis]], [[leishmaniasis]], [[Chagas disease]], and [[toxoplasmosis]]. Seattle is a hug for global health research, and in July 2012, Seattle Magazine honored two Seattle BioMed leaders (Dr. Stuart and Theresa Britschgi, Director of BioQuest) as "Top Docs" for the work they're doing in research and scientific training.<ref>http://seattlemag.com/gallery/top-doctors-2012-global-health-awards/</ref>


As part of a broad global initiative to fight malaria, Seattle BioMed developed its malaria program in 2000, with an initial grant from the [[Bill & Melinda Gates Foundation]]. With a three-pronged approach, Seattle BioMed's malaria program is focused on vaccine discovery for pregnancy malaria, severe malaria in children, and liver-stage malaria. In 2005, Seattle BioMed received two Grand Challenges in Global Health grants to accelerate its malaria research.<ref>http://www.grandchallenges.org/Pages/GCGHGrantsAwarded.aspx?TDate=Grand%20Challenges%20Grants%20%E2%80%93%20May%202005/</ref> And in 2011, Seattle BioMed was granted another $9 million from the Foundation to support malaria vaccine efforts.<ref>http://www.xconomy.com/seattle/2011/04/27/seattle-biomed-nabs-9m-gates-foundation-grant-to-develop-malaria-vaccines/</ref>
==Research & Funding News==
Seattle BioMed performs research on four areas of infectious disease:[[HIV/AIDS]], [[malaria]], [[tuberculosis|tuberculosis (TB)]], and Emerging & Neglected Diseases (END) like [[African sleeping sickness|African trypanosomiasis]], [[leishmaniasis]], [[Chagas disease]], and [[toxoplasmosis]].

===Top Docs===
Seattle is a hug for global health research, and in July 2012, Seattle Magazine honored two Seattle BioMed leaders (Dr. Stuart and Theresa Britschgi, Director of BioQuest) as "Top Docs" for the work they're doing in research and scientific training.<ref>http://seattlemag.com/gallery/top-doctors-2012-global-health-awards/</ref>

===Malaria===
As part of a broad global initiative to fight malaria, Seattle BioMed developed its malaria program in 2000, with an initial grant from the [[Bill & Melinda Gates Foundation]]. With a three-pronged approach, Seattle BioMed's malaria program focuses on vaccine discovery for pregnancy malaria, severe malaria in children, and liver-stage malaria. In 2005, Seattle BioMed received two Grand Challenges in Global Health grants to accelerate its malaria research.<ref>http://www.grandchallenges.org/Pages/GCGHGrantsAwarded.aspx?TDate=Grand%20Challenges%20Grants%20%E2%80%93%20May%202005/</ref> And in 2011, Seattle BioMed was granted another $9 million from the Foundation to support malaria vaccine efforts.<ref>http://www.xconomy.com/seattle/2011/04/27/seattle-biomed-nabs-9m-gates-foundation-grant-to-develop-malaria-vaccines/</ref>


In 2010, Dr. Stefan Kappe developed his own malaria vaccine candidate which is a weakened form of the malaria parasite, and tht vaccine candidate is undergoing clinical trials at [[Walter Reed Army Medical Center|Walter Reed]] near Washington, D.C.<ref>http://www.nature.com/nature/journal/v484/n7395_supp/full/484S24a.html/</ref> Soon after, in collaboration with PATH's Malaria Vaccine Initiative, Seattle BioMed became home to one of four malaria clinical trial centers in the world where treatments and vaccines can be safely tested in humans using the human challenge model.<ref>http://www.xconomy.com/seattle/2010/03/26/nine-years-in-the-making-seattle-biomeds-malaria-vaccine-on-verge-of-first-human-trial/</ref>
In 2010, Dr. Stefan Kappe developed his own malaria vaccine candidate which is a weakened form of the malaria parasite, and tht vaccine candidate is undergoing clinical trials at [[Walter Reed Army Medical Center|Walter Reed]] near Washington, D.C.<ref>http://www.nature.com/nature/journal/v484/n7395_supp/full/484S24a.html/</ref> Soon after, in collaboration with PATH's Malaria Vaccine Initiative, Seattle BioMed became home to one of four malaria clinical trial centers in the world where treatments and vaccines can be safely tested in humans using the human challenge model.<ref>http://www.xconomy.com/seattle/2010/03/26/nine-years-in-the-making-seattle-biomeds-malaria-vaccine-on-verge-of-first-human-trial/</ref>


BioQuest Academy is a [[STEM fields|STEM]] pipeline, and sometimes even "hooks" students into science by accident.<ref>http://humanosphere.org/2012/04/hooked-on-science-by-accident-kimberly-choi-puts-it-to-work-in-the-global-community/</ref>

==Training & Education==
As part of its training & education initiative, Seattle BioMed offers a program for high schoolers called BioQuest. One program offered by BioQuest is BioQuest Academy, a "biomedical boot camp" for 11th graders with over 60 hours (two weeks) of intensive instruction through a global health curriculum.<ref>http://www.laughingcrowcurriculum.com/portfolio/bioquest-academy-curriculum/</ref> BioQuest Academy is a [[STEM fields|STEM]] pipeline, and sometimes even "hooks" students into science by accident.<ref>http://humanosphere.org/2012/04/hooked-on-science-by-accident-kimberly-choi-puts-it-to-work-in-the-global-community/</ref>

In addition to the Academy, BioQuest also offers opportunities for high schoolers to learn more about global health within the formal school setting and state standards through its global health curriculum. This curriculum teaches algebra, history, and chemistry through the lens of global health.<ref>http://www.seattlebioquest.org/content/wgha-ambassador-program/</ref>


==Community Engagement==
Seattle BioMed offers many ways for community members to learn more about global health, including its annual Passport to Global Health Celebration.<ref>http://www.seattleglobalist.com/event/passport-to-global-health-celebration/</ref> The Institute also participates in events for grade schoolers like the South Lake Union Science Trek<ref>https://www.systemsbiology.org/ssf2012/seattlebiomed.html/</ref>.


==References==
==References==

Revision as of 20:40, 8 November 2012

Seattle BioMed
Company typeNon-profit organization
IndustrieBiomedical research, Global health, Infectious disease
Gegründet1976
GründerKen Stuart Edit this on Wikidata
HauptsitzSeattle, Washington
Key people
Alan Aderem, President
Number of employees
360+
ParentSeattle Children's Research Institute Edit this on Wikidata
Websitehttp://www.seattlebiomed.org/

Seattle BioMed, known prior to 2010 as Seattle Biomedical Research Institute or SBRI, is the largest independent, non-profit organization in the United States focused solely on infectious disease discovery research. The mission of Seattle BioMed's 360+ employees is to eliminate the world's most devastating infectious diseases through leadership in scientific discovery. Seattle BioMed is headquartered and has research labs in the South Lake Union area of Seattle, WA and has field labs in Tanzania. Seattle BioMed's research focuses on four areas of infectious disease: HIV/AIDS, malaria, tuberculosos (TB), and Emerging & Neglected Diseases (END) like African trypanosomiasis, leishmaniasis, Chagas disease, and toxoplasmosis. Seattle BioMed is engaged in early stages of the scientific pipeline including bench science and clinical trials and has expertise in immunology, vaccinology, and drug discovery.

History

Seattle BioMed headquarters on Westlake Avenue

In 1976, founders Ruth W. Shearer, Ph.D., and Kenneth Stuart, Ph.D., set up a research laboratory in Issaquah, WA. Originally called the Issaquah Group for Health and Environmental Research, the name was soon changed to Issaquah Biomedical Research Institute. Scientists at the Institute studied parasites including ones that cause malaria and African sleeping sickness. In 1986, the Institute relocated to Seattle, Washington to enhance its scientific programs and became Seattle Biomedical Research Institute.[1]

In January 2012, Alan Aderem, Ph.D. became president of Seattle BioMed, only the second in its 36 year history, with Dr. Stuart remaining in an active role as President Emeritus and Founder. As part of the Institute's plan for scientific expansion, Dr. Aderem is leading the implementation of integrating systems biology approaches to understanding infectious disease.[2]

Current Research

Seattle BioMed performs research on four areas of infectious disease:HIV/AIDS, malaria, tuberculosis (TB), and Emerging & Neglected Diseases (END) like African trypanosomiasis, leishmaniasis, Chagas disease, and toxoplasmosis. Seattle is a hug for global health research, and in July 2012, Seattle Magazine honored two Seattle BioMed leaders (Dr. Stuart and Theresa Britschgi, Director of BioQuest) as "Top Docs" for the work they're doing in research and scientific training.[3]

As part of a broad global initiative to fight malaria, Seattle BioMed developed its malaria program in 2000, with an initial grant from the Bill & Melinda Gates Foundation. With a three-pronged approach, Seattle BioMed's malaria program is focused on vaccine discovery for pregnancy malaria, severe malaria in children, and liver-stage malaria. In 2005, Seattle BioMed received two Grand Challenges in Global Health grants to accelerate its malaria research.[4] And in 2011, Seattle BioMed was granted another $9 million from the Foundation to support malaria vaccine efforts.[5]

In 2010, Dr. Stefan Kappe developed his own malaria vaccine candidate which is a weakened form of the malaria parasite, and tht vaccine candidate is undergoing clinical trials at Walter Reed near Washington, D.C.[6] Soon after, in collaboration with PATH's Malaria Vaccine Initiative, Seattle BioMed became home to one of four malaria clinical trial centers in the world where treatments and vaccines can be safely tested in humans using the human challenge model.[7]

BioQuest Academy is a STEM pipeline, and sometimes even "hooks" students into science by accident.[8]

References

47°37′16″N 122°20′20″W / 47.62111°N 122.33889°W / 47.62111; -122.33889