Apricoxib: Difference between revisions
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| molecular_weight = 356.4387 g/mol |
| molecular_weight = 356.4387 g/mol |
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| smiles = CCOC1=CC=C(C=C1)C2=CC(=CN2C3=CC=C(C=C3)S(=O)(=O)N)C |
| smiles = CCOC1=CC=C(C=C1)C2=CC(=CN2C3=CC=C(C=C3)S(=O)(=O)N)C |
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| StdInChI = 1S/C19H20N2O3S/c1-3-24-17-8-4-15(5-9-17)19-12-14(2)13-21(19)16-6-10-18(11-7-16)25(20,22)23/h4-13H,3H2,1-2H3,(H2,20,22,23) |
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| StdInChIKey = JTMITOKKUMVWRT-UHFFFAOYSA-N |
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Revision as of 20:49, 5 April 2016
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Chemical and physical data | |
Formula | C19H20N2O3S |
Molar mass | 356.4387 g/mol g·mol−1 |
3D model (JSmol) | |
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Apricoxib is an experimental anticancer drug in Phase II clinical trials. It is a COX-2 inhibitor which improves standard therapy response in molecularly defined models of pancreatic cancer.[1]
See also
References
- ^ Kirane, A. (2012). "Apricoxib, a Novel Inhibitor of COX-2, Markedly Improves Standard Therapy Response in Molecularly Defined Models of Pancreatic Cancer". Clinical Cancer Research. 18 (18): 5031–5042. doi:10.1158/1078-0432.CCR-12-0453.