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Polar aprotic solvent

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A polar aprotic solvent is a solvent that lacks an acidic proton and is polar. Such solvents lack hydroxyl and amine groups. In contrast to protic solvents, these solvents do not serve as proton donors in hydrogen bonding, although they can be proton acceptors. Many solvents, including chlorocarbons and hydrocarbons, are classifiable as aprotic, but polar aprotic solvents are of particular interest for their ability to dissolve salts.

Solvent Chemical formula Boiling point Dielectric constant Density Dipole moment (D)


Polar aprotic solvents
acetone C3H6O 56.05 °C 21.83 0.7845 g/cm3 2.91
acetonitrile CH3CN 81.3 - 82.1 °C 38.3 0.776 g/cm3 3.20
dichloromethane CH2Cl2 39.6 °C 9.08 1.3266 g/cm3 1.6
dimethylformamide (CH3)2NCHO 153 °C 36.7 0.95 g/cm3 3.86
dimethylpropyleneurea (CH3)2C4H6N2O 246.5 °C 36.12 1.064 g/cm3 4.23
dimethylsulfoxide (CH3)2SO 189 °C 46.7 1.1 g/cm3 3.96
ethyl acetate C4H8O2 77.11°C 6.02 0.902 g/cm3 1.88
hexamethylphosphoric triamide [(CH3)2N]3PO 232.5 °C 29.6 1.03 g/cm3 5.38
tetrahydrofuran C4H8O 66 °C 7.6 0.887 g/cm3 1.75


References