Thyrotropin receptor
Appearance
Template:PBB The thyrotropin receptor (or TSH receptor) is a gene (and associated protein) which responds to thyroid-stimulating hormone (also known as "thyrotropin", and stimulates the production of thyroxine (T4) and triiodothyronine (T3). The TSH receptor is a member of the G-protein coupled receptor superfamily of integral membrane proteins.[1]
It is primarily found on the surface of the thyroid epithelial cells.
It should not be confused with "thyrotropin-releasing hormone" (TRH) or "thyrotropin-releasing hormone receptor" (TRHR).
See also
Further reading
External links
- "Glycoprotein Hormone Receptors: TSH". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.
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(help) - Thyrotropin+Receptors at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- GRIS: Glycoprotein-hormone Receptor Information System
References
- ^ Farid NR, Szkudlinski MW (2004). "Minireview: structural and functional evolution of the thyrotropin receptor". Endocrinology. 145 (9): 4048–57. doi:10.1210/en.2004-0437. PMID 15231707.