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Perry Rosenthal

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This is an old revision of this page, as edited by Csinacola (talk | contribs) at 20:46, 15 September 2015 (→‎Theory and definition of oculofacial pain as a disease). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

  • Comment: There are only 2 third-party articles here: the NY Times one and the Chicago Tribune. The remainder are links to articles by him, or directory listings where he does or has worked, and should be removed, along with article content they support. Among the awards, the Donald R Korb award is here: [1], but I have no idea how significant that is. Speaking engagements are not awards. When cut down to the verifiable facts, this article becomes quite short. LaMona (talk) 21:26, 1 September 2015 (UTC)
  • Comment: you still don't have sources for his early life and early career. The Gerald Tulchinsky book does not mention Rosenthal, just supports the statement about university practices, but that doesn't verify statements about his personal educational history. It would be better to drop the personal information that you cannot source and concentrate entirely on information available from articles you have referenced here. What will make him notable is his scientific work, not personal information. LaMona (talk) 01:07, 31 August 2015 (UTC)
  • Comment: This is essentially an advertisement for this theory. It's usually not a great idea to go to the trouble of giving permission for copying a persons website , because what makes a good personal website or press release rarely makes a good WP article.
    If his theory is to be discussed here, there must be references providing substantial coverage from third-party independent reliable sources about it that show its importance. For a medical topic this usually requires sources of quality that meets WP:MEDRS. There are no such sources present here.
    There is presently no evidence for meeting either the WP:PROF or the WP:GNG standard.
    Please do not resubmit until you havethe necessary 3rd party references     DGG ( talk ) 20:27, 14 August 2015 (UTC)
  • Comment: May or may not be notable. Need more references. See WP:BIO for how to show notability, and WP:RS as to what is a reliable source. Onel5969 TT me 22:31, 13 August 2015 (UTC)
File:Dr.PerryRosenthal.jpg
Dr. Perry Rosenthal

Dr. Perry Rosenthal (born September 2, 1933), is a Canadian-born American eye surgeon and professor of ophthalmology, known for his work in the development of the first gas-permeable scleral contact lens[1]. He became founding president of the non-profit Boston Foundation for Sight in 1992, and was its president and a director until 2012. In 2013, he founded the non-profit Boston EyePain Foundation, in Chestnut Hill, Massachusetts. Dr. Rosenthal has written and lectured extensively on contact lenses and corneal disease.

Early life and education

Dr. Rosenthal was born in Montreal, Quebec, Canada, the older of the two children of Max Rosenthal and Sabina Slater. He attended high school in Outremont, a borough within Montreal, and studied piano under a scholarship at the Conservatory of Music and Dramatic Art (Conservatoire de musique et d'art dramatique du Québec). In May 1954, he received a Bachelor of Science degree from McGill University. In May 1958, he received a Doctor of Medicine degree from McGill University Medical School, having worked closely with a mentor, Dr. R.V.V. Nichols, a Montreal ophthalmologist who taught at McGill University Medical School.

Career

Following his graduation, Dr. Rosenthal completed his internship at Montreal General Hospital from July 1958 through July 1959. From September 1959 until April 1960, he completed a basic science course in ophthalmology at Harvard Medical School, Boston, Massachusetts. He served as a resident in ophthalmology at the Massachusetts Eye and Ear Infirmary between July 1960 and January 1963, then joined the infirmary staff. From 1963 to 1998, Dr. Rosenthal was in private practice and a staff surgeon at the Massachusetts Eye and Ear Infirmary. He was then named to the infirmary’s courtesy staff, and, since 2013, has been an emeritus member.[2] Dr. Rosenthal has been a part-time Assistant Clinical Professor in Ophthalmology at Harvard Medical School since 1984. [3]

Work on contact lenses

While training as a resident at Harvard's Massachusetts Eye and Ear Infirmary, Dr. Rosenthal founded the hospital's contact lens clinic. He subsequently became a co-founder of Polymer Technology Inc., which developed Boston Lens products, including the first advanced rigid gas-permeable plastic that allowed the corneas to breathe normally through the contact lenses. Polymer Technology Inc. was subsequently acquired by Bausch & Lomb, of which Dr. Rosenthal became a director. In 1986, Dr. Rosenthal developed the first practical, gas-permeable scleral contact lens to treat and restore vision of eyes with many corneal diseases.[4] Such lenses have since been widely adopted in clinical practice, with ongoing research and development to improve them. [5][6]In 1992, Dr. Rosenthal created the non-profit Boston Foundation for Sight to provide these devices to all whom they can benefit, regardless of their ability to pay.

Work on oculofacial pain

While at the Boston Foundation for Sight, Dr. Rosenthal observed patients suffering from unusually severe, unrelenting eye pain often accompanied by disabling headaches, hypersensitivity to light and/or pain perceived as originating from their ears, around and behind their eyes, face and even jaws and teeth. Nevertheless, because their eyes and other areas above their neck perceived as the source of pain were normal on detailed examinations, these patients were often believed to be exaggerating or fabricating their symptoms.[7]

Theory and definition of oculofacial pain as an overlooked disease of the trigeminal pain system

Dr. Rosenthal examined 200 patients with this disease of the pain system, of whom 21 had undergone laser-assisted in situ keratomileusis (LASIK) or similar corneal surgery prior to the onset of this disease of the trigeminal pain system. Dr. Rosenthal outlined his theory in a paper titled Chronic Pain Following Laser Keratorefractive Surgery [8], suggesting that the pain is projected from a pain-modulating center in the brain, and that its perceived origins are an illusion, thereby explaining the remarkable disparity between symptoms and signs of their cause.

British Journal of Ophthalmology article and continuing controversy

On May 5, 2015, the British Journal of Ophthalmology published a paper by Dr. Rosenthal and Dr. David Borsook describing a fundamentally new theory of dry eye disease.[9] They argued that there are two principal categories of this disease; "true" dry eye caused by damaged tear-producing glands, and a second in which chronic dry eye symptoms are caused by malfunctions in the nerves of the dry eye alarm that evolved to monitor the tear film thickness, and trigger dry eye symptoms when evaporation has thinned the eye's tear film to the point of it threatening to break up and degrade vision. They posit that many if not most dry eye-like symptoms represent hypersensitivity to tear evaporation similar to false alarms. In other words, the dry eye alarm has become hypersensitive, thereby misinterpreting the thickness of the tear film as being thinner than it is. Moreover, this corneal nerve disease over time does interfere with the secretion of tears, resulting in their becoming drier over time. Dr. Rosenthal's theory remains controversial, with other researchers challenging his description of the disease, and whether it has any link to LASIK surgery.[10]

Current professional activities

Although no longer in practice, Dr. Rosenthal is actively involved in supervising his nonprofit’s website and providing informational resources for patients. He collaborates, without charge, with doctors whose patients are experiencing oculofacial pain, to educate them about this condition and to help in formulating new treatment options. Dr. Rosenthal also continues to appear at conferences and symposiums in the U.S. and abroad, as a lecturer and panelist.[11]

Personal life

Dr. Rosenthal married Zelda Shochet, and the couple had three children - William Rosenthal, Dr. Beth A. Schaff, and Dr. Steven Rosenthal (1960-2010). Zelda Rosenthal died in 2009. Dr. Rosenthal resides in Brookline, Massachusetts.

Honors and awards

• 1956 Alpha Omega Alpha Honor Medical Society

• 1957 University Scholar, McGill University

• 1987 Trailblazer’s Award, Contact Lens Manufacturers Association (CLMA)

• 1994 Joseph Dallos Award (CLMA), given annually for "outstanding contribution to the development and advancement of the contact lens industry and for service to humanity," in memory of the Hungarian-born British ophthalmologist Josef Dallos, a pioneer in the development of the first contact lenses.[12]

• 2002 Named a Tech Laureate by the Tech Museum of Innovation, San Jose, California, for technology benefiting humanity. http://thetechawards.thetech.org/laureate/archive

• 2005-2012 Best Doctors in America

• 2007 Founders Award: American Academy of Optometry; http://www.aaopt.org/fellows/awards/sections

• 2007 UHCO Award for Distinguished Research on the Cornea and Contact Lenses, University of Houston College of Optometry

• 2012 Dr. Donald R. Korb Award for Excellence, annual meeting of the American Optometric Association

• 2015 Honored by Ora, Inc., as a visiting scholar in dry-eye disease

Publications

1. Leibowitz H.M., Rosenthal P. "Hydrophilic contact lenses in corneal disease."[13]Archives of Ophthalmology, 1971; 85: 163-6, 283-6.

2. Rosenthal P. "A clinical evaluation of the RX56 contact lens." Contact and Intraocular Lens Medical Journal, 1976; 220-5.

3. Sendele D., Kenyon K.R., Mobilia E.F., Rosenthal P. "Superior limbic keratoconjunctivitis in contact lens wearers."[14] Ophthalmology, 1983; 90: 616-22.

4. Chou M.H., Rosenthal P., Salomone S.C. "Efficacy of cleaning solutions on silicone/acrylate gas-permeable contact lens materials." Contact Lens Forum, August 1985.

5. Rosenthal P., Chou M.H., Salamone S.C. "Quantitative analysis of chlorhexidine gluconate and benzalkonium chloride adsorption on silicone/acrylate polymers." Cataract and Intraocular Lens Medical Journal, 1986; 1:43-50.

6. Schein O.D., Rosenthal P., Ducharme C. "A gas-permeable scleral contact lens for visual rehabilitation." American Journal of Ophthalmology, 1990; 109: 318.

7. Rosenthal P., Cotter J.M. "Clinical performance of a spline-based apical vaulting keratoconus corneal contact lens design." CLAO Journal, 1995; 21: 42-46.

8. Cotter J.M., Rosenthal P. "Scleral contact lenses." Journal of the American Optometric Association, 1998; 69: 33-40.

9. Rosenthal, P., Cotter, J.M, Baum, J. "Treatment of persistent epithelial defect with extended wear of a fluid-ventilated gas permeable scleral contact lens."[15] American Journal of Ophthalmology, 2000; 130: 33-41.

10. Romero-Rangel, T., Stavrou, P., Cotter, J., Rosenthal, P., Foster, S. "Gas permeable scleral lens therapy in ocular surface disease." American Journal of Ophthalmology, 2000; 130: 25-32.

11. Rosenthal, P., Croteau, A. "Fluid-Ventilated, gas-permeable scleral contact lens is an effective option for managing severe ocular surface disease and many corneal disorders that would otherwise require penetrating keratoplasty." Eye & Contact Lens, 2005; 31 (3) (130-134).

12. Takahide, K., Parker, P., Rosenthal, P., et al. "Use of Fluid-Ventilated, Gas-Permeable Scleral Lens for Management of Severe Keratoconjunctivitis Sicca Secondary to Chronic Graft-Versus-Host Disease." Biology of Blood and Marrow Transplantation, 2007; 13: 1016-1021.

13. Jacobs, D.S., Rosenthal, P. "Boston Lens Prosthetic Device for Treatment of Severe Dry Eye in Chronic Graft-Versus-Host Disease." Cornea, 2007; 26 (10): 1195-1195.

14. Borsook, D., Rosenthal, P. "Chronic (neuropathic) Corneal pain and Blepharospasm: five case reports." Pain, 2011; 152: 2427-31.

15. Rosenthal, P., Borsook, D. "The corneal pain system. Part I: the missing piece of the dry eye puzzle." The Ocular Surface, 2012; 10(1): 2-14.

16. Moulton E.A., Becerra L., Rosenthal P., Borsook D. (2012) "An Approach to Localizing Corneal Pain Representation in Human Primary Somatosensory Cortex." PLoS ONE 7(9): e44643. doi:10.1371/journal.pone.0044643.

17. Rosenthal, P., Borsook, D. "Ocular neuropathic pain." British Journal of Ophthalmology, 2015; 0:1–7. doi:10.1136/bjophthalmol-2014-306280.[16]

References

  1. ^ http://www.nytimes.com/2003/07/01/health/a-new-lens-restores-vision-and-brings-relief.html
  2. ^ http://www.masseyeandear.org/for-professionals/physician-resources/staff-listing/ophthalmology
  3. ^ https://connects.catalyst.harvard.edu/Profiles/display/Person/55625
  4. ^ http://www.ajo.com/article/S0002-9394%2814%2974558-1/abstract?cc=y=
  5. ^ http://articles.chicagotribune.com/2002-09-01/news/0209010406_1_lenses-guide-dog-lomb
  6. ^ http://www.clspectrum.com/articleviewer.aspx?articleID=106972
  7. ^ http://development.aao.org/publications/eyenet/201007/upload/29_CUcornea_FF_copy.pdf
  8. ^ http://www.bostoneyepain.org/chronic-pain-following-laser-keratorefractive-surgery-2/
  9. ^ http://bjo.bmj.com/content/early/2015/05/19/bjophthalmol-2014-306280
  10. ^ http://mosaicscience.com/story/severe-eye-pain
  11. ^ http://www.optometry.org.au/blog-news/2015/5/4/australian-contact-lens-pioneer-receives-global-recognition.aspx
  12. ^ http://www.andrewgasson.co.uk/pioneers_dallos.htm
  13. ^ http://archopht.jamanetwork.com/article.aspx?articleid=630179
  14. ^ http://www.ncbi.nlm.nih.gov/pubmed/6888855
  15. ^ http://www.ajo.com/article/S0002-9394%2800%2900379-2/references
  16. ^ http://bjo.bmj.com/content/early/2015/05/03/bjophthalmol-2014-306280.full.pdf+html

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