Nebacumab: Difference between revisions
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Script assisted update of identifiers for the Chem/Drugbox validation project (updated: 'CAS_number'). |
Entranced98 (talk | contribs) Adding local short description: "Monoclonal antibody", overriding Wikidata description "chemical compound" |
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{{Drugbox |
{{Drugbox |
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| Verifiedfields = changed |
| Verifiedfields = changed |
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| verifiedrevid = |
| verifiedrevid = 458283142 |
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| image = |
| image = |
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<!-- Monoclonal antibody data --> |
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| type = mab |
| type = mab |
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| mab_type = mab |
| mab_type = mab |
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| source = u |
| source = u |
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| target = endotoxin |
| target = endotoxin |
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| tradename = |
| tradename = |
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| Drugs.com = {{drugs.com|international|nebacumab}} |
| Drugs.com = {{drugs.com|international|nebacumab}} |
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| legal_status = |
| legal_status = |
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| routes_of_administration = |
| routes_of_administration = |
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| bioavailability = |
| bioavailability = |
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| protein_bound = |
| protein_bound = |
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| elimination_half-life = |
| elimination_half-life = |
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| excretion = |
| excretion = |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = 908FWN27WK |
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| ATC_prefix = J06 |
| ATC_prefix = J06 |
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| ATC_suffix = BC01 |
| ATC_suffix = BC01 |
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| KEGG = D05126 |
| KEGG = D05126 |
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| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} |
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} |
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| ChemSpiderID = |
| ChemSpiderID = none |
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| chemical_formula = |
| chemical_formula = |
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| molecular_weight = |
| molecular_weight = |
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'''Nebacumab''' is a [[human]] [[monoclonal antibody]] developed for the treatment of [[sepsis]].<ref>{{ |
'''Nebacumab''' is a [[human]] [[monoclonal antibody]] developed for the treatment of [[sepsis]].<ref>{{cite journal | vauthors = Derkx B, Wittes J, McCloskey R | title = Randomized, placebo-controlled trial of HA-1A, a human monoclonal antibody to endotoxin, in children with meningococcal septic shock. European Pediatric Meningococcal Septic Shock Trial Study Group | journal = Clinical Infectious Diseases | volume = 28 | issue = 4 | pages = 770–7 | date = April 1999 | pmid = 10825037 | doi = 10.1086/515184 | doi-access = free }}</ref> It has been withdrawn in 1993 because it failed to reduce mortality in [[clinical trial]]s.<ref>[https://web.archive.org/web/20091107133217/http://apps.who.int/medicinedocs/en/d/Js4902e/4.1.262.html#Js4902e.4.1.262 WHO: Consolidated List of Products]</ref> |
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==References== |
== References == |
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{{reflist}} |
{{reflist}} |
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{{Immune sera and immunoglobulins}} |
{{Immune sera and immunoglobulins}} |
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[[Category:Withdrawn drugs]] |
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[[Category:Abandoned drugs]] |
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{{antiinfective-drug-stub}} |
{{antiinfective-drug-stub}} |
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{{monoclonal-antibody-stub}} |
{{monoclonal-antibody-stub}} |
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