PEG 400: Difference between revisions

| verifiedrevid = 265828401

| Name = Polyethylene glycol

| ImageFile = Polyethylene glycol.png

| ImageName = Polyethylene glycol

| IUPACName = Polyethylene glycol

| Section1 = {{Chembox Identifiers

| CASNo_Ref = {{cascite}}

| CASNo = 25322-68-3

| Section2 = {{Chembox Properties

| Formula = C_2nH_4n+2O_n+1, n = 8.2 to 9.1

| MolarMass = 380-420 g/mol

| Density = 1.128 g/cm³

| Viscosity = 90.0 cSt at 25 °C, 7.3 cSt at 99 °C

| MeltingPt = 4-8 °C

| Section7 = {{Chembox Hazards

| FlashPt = 238 °C

| LD50 = 30 mL/kg, orally in rats

'''PEG 400''' (polyethylene glycol 400) is a low molecular weight grade of [[polyethylene glycol]]. It is a clear, colorless, viscous liquid. Due in part to its low toxicity, PEG 400 is widely used in a variety of pharmaceutical formulations.

PEG 400 is strongly [[hydrophilic]]. The [[partition coefficient]] of PEG 400 between hexane and water is 0.000015 (log<math>P = -4.8</math>), indicating that when PEG 400 is mixed with water and hexane, there are only 1.5 parts of PEG 400 in the hexane layer per 100,000 parts of PEG 400 in the water layer.<ref>{{cite journal

| title= PEG 400, a hydrophilic molecular probe for measuring intestinal permeability

| author= T. Y. Ma, D. Hollander, P. Krugliak, K. Katz

| journal= Gastroenterology

| volume= 98

| issue= 1

| pages= 39–46

| year= 1990

| url= http://www.gastrojournal.org/article/PII001650859091288H/abstract

| pmid= 2293598}}</ref>

PEG 400 is soluble in water, acetone, alcohols, benzene, glycerin, glycols, aromatic hydrocarbons and is slightly soluble in aliphatic hydrocarbons.